Protein Alignment CG6231 and Slc22a3

DIOPT Version :9

• Sequence 1: NP_001262734.1
• Gene: CG6231 / 42339
• FlyBaseID: FBgn0038720
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_035525.1
• Gene: Slc22a3 / 20519
• MGIID: 1333817
• Length: 551
• Species: Mus musculus
• Alignment Length: 566
• Identity: 151/566 - (26%)
• Similarity: 256/566 - (45%)
• Gaps: 83/566 - (14%)

  Fly     3 FDQILAKCGDFNRYQ---FMILALFG------FINIIVSMHYFTQTVISFVPD-HWCYHDKLV-- 55
            |||.|.|.|:|.|:|   |::|.|.|      |:.::         .:...|| :||...:..
Mouse     4 FDQALRKAGEFGRFQRRVFLLLCLTGVTFAFLFVGVV---------FLGSQPDYYWCRGPRATAL 59

  Fly    56 ------------NMTYKEIGEIYAQFENPSCTR--LDDINGHNVTVSSKACE------------- 93
                        |:|..|:.....:.....|.|  |:..|    |.|..:|:
Mouse    60 AERCAWSPEEEWNLTTPELHVPAERRGQGHCHRYLLEATN----TSSELSCDPLTAFPNRSAPLV 120

  Fly    94 ----KWIYNYDFGYRSMNTELNWVCDSAYKARIGQSLFFIGSVVGTLFYGLLSDKIGRVPALILS 154
                .|  .|...:.::.::.:.||.:|:...:.|::..:|.:.|....|..:|:.||:...::|
Mouse   121 SCSGDW--RYVETHSTIVSQFDLVCSNAWMLDLTQAILNLGFLAGAFTLGYAADRYGRLIIYLIS 183

  Fly   155 NF-CGFAGDFSTIFTKSVATFTLCRFISGLAADTNFYLMYIIVLEYIRPSMRTLGLNMAVGLFYC 218
            .| .|..| ....|..:.:.|.:.||:.|:.....:...::||.|.:....|.: :.:.:.:|:.
Mouse   184 CFGVGITG-VVVAFAPNFSVFVIFRFLQGVFGKGAWMTCFVIVTEIVGSKQRRI-VGIVIQMFFT 246

  Fly   219 LGLVFTPWLAVLVGHWQIYLACTSLPILLVVLYYFVVQESAQWLVTRNDIDGAIVRLKRVAKFNG 283
            ||::..|.:|.....||......|||..|.:|||:||.||.:||:||...:.|:..|:||||.||
Mouse   247 LGIIILPGIAYFTPSWQGIQLAISLPSFLFLLYYWVVPESPRWLITRKQGEKALQILRRVAKCNG 311

  Fly   284 CRVSQADFDEFRRHCQMTHEMLGGDDKKQATLLDMFRTPRMRKNTLILFFKSMVITLCYDAVSRN 348
            ..:| :::.|.    .:|.|     :....:.||:.|||:|||.||||.|......:.|..:...
Mouse   312 KHLS-SNYSEI----TVTDE-----EVSNPSCLDLVRTPQMRKCTLILMFAWFTSAVVYQGLVMR 366

  Fly   349 VEGMGISPFIMFSLSALAVLPSSVLLVLLQDRIGRKGMASGSLLVGG---LFTAAAGIAIAYQQH 410
            :..:|.:.:|.|.:|.|..||.::|::|..:|:||:...:.|.:|.|   |.||.....|.:
Mouse   367 LGLIGGNLYIDFFISGLVELPGALLILLTIERLGRRLPFAASNIVAGVSCLVTAFLPEGIPW--- 428

  Fly   411 NHNAILLACLTIAARFGVAISYESGSQYATELIPTCVRGQGVAAVHVAGFAASFLAPYILW-LGT 474
                 |...:....|.|:.:::|......:||.||.:|..||:...........:||::|: |..
Mouse   429 -----LRTTVATLGRLGITMAFEIVYLVNSELYPTTLRNFGVSLCSGLCDFGGIIAPFLLFRLAA 488

  Fly   475 FFKAAPSIILGVLFFAGSFVCLLLPETLNRSLPTTIEEGEVFGKGE 520
            .:...|.||.|:|......:.:|||||...:||.|:|:.|..|..:
Mouse   489 IWLELPLIIFGILASVCGGLVMLLPETKGIALPETVEDVEKLGSSQ 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6231	NP_001262734.1	2A0119	11..509	CDD:273328	142/545 (26%)
		MFS	125..499	CDD:119392	107/378 (28%)
Slc22a3	NP_035525.1	2A0119	12..523	CDD:273328	142/545 (26%)
		MFS	145..513	CDD:119392	109/387 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844072
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.950