Protein Alignment CG6231 and Slc22a2

DIOPT Version :9

• Sequence 1: NP_001262734.1
• Gene: CG6231 / 42339
• FlyBaseID: FBgn0038720
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_038695.1
• Gene: Slc22a2 / 20518
• MGIID: 1335072
• Length: 553
• Species: Mus musculus
• Alignment Length: 564
• Identity: 147/564 - (26%)
• Similarity: 251/564 - (44%)
• Gaps: 91/564 - (16%)

  Fly     4 DQILAKCGDFNRYQ---FMILALF--GFINIIVSMHYFTQTVISFVPDHWCYHDKL--------- 54
            |.||...|:|:.:|   |.:|||.  .|..|.|.:.:     :.|.|:|.|....:
Mouse     5 DDILEHIGEFHLFQKQTFFLLALLSGAFTPIYVGIVF-----LGFTPNHHCRSPGVAELSQRCGW 64

  Fly    55 -----VNMTYKEIGEIYAQFENPSCTR---------LDDINGHNVTVSSKA------CEK-WIYN 98
                 :|.|...:|..........|.|         ||.::..:...::::      ||. |:
Mouse    65 SPAEELNYTVPGLGSAGEVSFLSQCMRYEVDWNQSTLDCVDPLSSLAANRSHLPLSPCEHGWV-- 127

  Fly    99 YDFGYRSMNTELNWVCDSAYKARIGQSLFFIGSVVGTLFYGLLSDKIGRVPALILSNFCGFAGDF 163
            ||....|:.||.|.||..::...:.|||..:|..:|.:..|.|:|:.||...|:::.........
Mouse   128 YDTPGSSIVTEFNLVCAHSWMLDLFQSLVNVGFFIGAVGIGYLADRFGRKFCLLVTILINAISGV 192

  Fly   164 STIFTKSVATFTLCRFISGLAADTNFYLMYIIVLEYIRPSMRTLGLNMAVGLFYCLGLVFTPWLA 228
            ....:.:.|...:.||:.||.:...:.:.||::.|::     .||....||:  |..:.||..|.
Mouse   193 LMAISPNYAWMLVFRFLQGLVSKAGWLIGYILITEFV-----GLGYRRTVGI--CYQIAFTVGLL 250

  Fly   229 VLVG------HWQIYLACTSLPILLVVLYYFVVQESAQWLVTRNDIDGAIVRLKRVAKFNGCRVS 287
            :|.|      :|:......:||....:||::.:.||.:||:::|....|:..:|.:||.||
Mouse   251 ILAGVAYALPNWRWLQFAVTLPNFCFLLYFWCIPESPRWLISQNKNAKAMKIIKHIAKKNG---- 311

  Fly   288 QADFDEFRRHCQMTHEMLGGDD----KKQATLLDMFRTPRMRKNTLILFFKSMVITLCYDAVSRN 348
                    :...::.:.|..|:    |...:.||:.|||::||:||||.:.....::.|..:..:
Mouse   312 --------KSVPVSLQSLTADEDTGMKLNPSFLDLVRTPQIRKHTLILMYNWFTSSVLYQGLIMH 368

  Fly   349 VEGMGISPFIMFSLSALAVLPSSVLLVLLQDRIGRKGMASGSLLVGGLFTAAAGIAIAYQQHNHN 413
            :...|.:.::.|..|||...|::.:::|..|||||:...:.|.:|.|    ||.:|..:...:..
Mouse   369 MGLAGDNIYLDFFYSALVEFPAAFIIILTIDRIGRRYPWAVSNMVAG----AACLASVFIPDDLQ 429

  Fly   414 --AILLACLTIAARFGVAISYESGSQYATELIPTCVRGQGV----AAVHVAGFAASFLAPYI--L 470
              .|.:|||   .|.|:.|:||.......||.||.:|...|    :...:.|....||...:  :
Mouse   430 WLKITVACL---GRMGITIAYEMVCLVNAELYPTYIRNLAVLVCSSMCDIGGIVTPFLVYRLTDI 491

  Fly   471 WLGTFFKAAPSIILGVLFFAGSFVCLLLPETLNRSLPTTIEEGE 514
            ||     ..|.::..|:......:.||||||..::||.|||:.|
Mouse   492 WL-----EFPLVVFAVVGLVAGGLVLLLPETKGKALPETIEDAE 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6231	NP_001262734.1	2A0119	11..509	CDD:273328	140/550 (25%)
		MFS	125..499	CDD:119392	101/391 (26%)
Slc22a2	NP_038695.1	2A0119	12..525	CDD:273328	140/550 (25%)
		MFS	125..492	CDD:119392	105/394 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843828
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.950