DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6231 and suex-2

DIOPT Version :9

Sequence 1:	NP_001262734.1	Gene:	CG6231 / 42339	FlyBaseID:	FBgn0038720	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_501556.2	Gene:	suex-2 / 183742	WormBaseID:	WBGene00008271	Length:	502	Species:	Caenorhabditis elegans

Alignment Length:	599	Identity:	120/599 - (20%)
Similarity:	209/599 - (34%)	Gaps:	174/599 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 RYQFMILALFGFINIIVSMHYFTQTVISFVPDHWCYHDKLVNMTYKEIGEIYAQFENPSCTRLDD 79
            |....::.|:. |.:|.|........:.|:|..:|..|   |..||...:....:::    ...:
Worm     6 RLDITVMVLYQ-ITLIFSAQLIFVIFLDFMPSTYCTDD---NFCYKLQSKCLMDYDH----NAQN 62

  Fly    80 INGHNVTVSSKAC-----EKWIYNYDFGYRSMNTELNWVCDSAYKARIGQSL---FFIGSVVGTL 136
            :...|:|.::..|     ..:..:..|.|:...|.||           |.||   .|||:::|.:
Worm    63 LCPVNMTENASKCIADHSRLFFRSAQFEYQQDCTGLN-----------GFSLSTATFIGTLLGNI 116

  Fly   137 FYGLLSDKIGRVPALILSNFCGFAGDFSTIFTKSVATFTLCRFISGLAADTNFYLMYIIVLEYIR 201
            ..|.|:||.||                .||:..|:.....|..:|  ||.||.|..||..:
Worm   117 ALGFLADKYGR----------------RTIYLSSLLFGIPCVVLS--AAITNIYSFYIFRI---- 159

  Fly   202 PSMRTLGLN----MAVGLFYCLGLV----------FTPW---------LAVLVGHWQ--IYL--- 238
                .:|::    :.||..|...::          |:.|         ||.:...|:  .|:
Worm   160 ----LIGISVSGTLTVGWTYATEMISPNRRLRILAFSNWPNARMIQVGLAYISQEWKTATYICAA 220

  Fly   239 -ACTSLPILLVVLYYFVVQESAQWLVTR---NDIDGAIVRLKRVAKFNGCRVSQADFDEFRRHCQ 299
             :|.|||||:      .:.||..||..:   .:...|..||:::.||..           ..|..
Worm   221 VSCLSLPILI------YLPESPIWLDQKQKYKNASKARKRLRKIGKFYS-----------NEHST 268

  Fly   300 MTHEMLGGDDKKQATLLDMFRTPRMRKNTLILFFKSMVITLCYDAVSRNVEGMGISPFIMFSLSA 364
            :.       ..::.|...:.:.|::|.:..::.|....:.|.......|...|..:.::...||.
Worm   269 VV-------ANRKFTPTRILKDPKLRNSFFMIIFMYFYVGLAVYITDLNGADMTKNLYLGQFLSG 326

  Fly   365 LAVLPSSVLLVLLQ---DRIGRKGMASGSLLVGGLFTAAAGIAI---------AYQQHNHNAILL 417
            |.:..:..::.:.:   ..:||:          .||..|..||:         .|.....:.:.|
Worm   327 LVLSIAQFIIGMTEPYLTGLGRR----------VLFLIAQFIAMLCYICILICLYLNWKGSFLYL 381

  Fly   418 ACLTIAARFGVAISYESGSQYAT-------------ELIPTCVRGQGVAAVHVAGFAASFLAPYI 469
            :..|:|              |||             ||:||.||....:..::.....:.||  .
Worm   382 SAYTLA--------------YATQSLCLEAAYLSLVELMPTDVRATAGSTANICMKIGTILA--T 430

  Fly   470 LWLGTFFKAAPSIILGVLFFAGSFVC----LLLPETLNRSLPTTIEEGEVFGKGERMFDFPCLHN 530
            |.....|...||     |||....:|    :|:...|..|     .|.::...|:...:....||
Worm   431 LTKPLKFAYEPS-----LFFINLSICTIGMILVFFKLEES-----READMKMIGQTNDNIASAHN 485

  Fly   531 KHDDEESESELEKY 544
            :.:......:|:.|
Worm   486 EEEMPNQTIQLKNY 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6231	NP_001262734.1	2A0119	11..509	CDD:273328	114/562 (20%)
CG6231	NP_001262734.1	MFS	125..499	CDD:119392	91/437 (21%)
suex-2	NP_501556.2	MFS	108..460	CDD:391944	89/432 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910