DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6231 and C06H5.6

DIOPT Version :9

Sequence 1:	NP_001262734.1	Gene:	CG6231 / 42339	FlyBaseID:	FBgn0038720	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_507509.3	Gene:	C06H5.6 / 180170	WormBaseID:	WBGene00007394	Length:	556	Species:	Caenorhabditis elegans

Alignment Length:	587	Identity:	141/587 - (24%)
Similarity:	252/587 - (42%)	Gaps:	86/587 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDFDQILAKCGDFNRYQFM-------ILALFGFINIIVSMHYFTQTV--ISFVPDHWCYHDKLVN 56
            :|.|::|...|.:.|||.:       :..||. :|::: |.:.|::|  :..:||     .:.::
Worm    25 LDADKVLTAFGKYGRYQMLAYVITTSVHMLFA-LNMMI-MPFITKSVEFLCDLPD-----PESID 82

  Fly    57 MTYKEIGEIYAQFENPSCTRLDDINGHNVTVSSKACEKWIYNYDFGYRS-MNTELNWVCDSAYKA 120
            ..:      ::.....|| .|.|.. .|:|:...|.....|||....:| :.::.:.||:....|
Worm    83 SAH------FSPLVGDSC-HLQDTQ-LNITIDCLAVNGASYNYLADKKSTITSDFDLVCEYQGMA 139

  Fly   121 RIGQSLFFIGSVVGTLFYGLLSDKIGRVPALILSNFCGFAGDFSTIFTKSVATFTLCRFISGLAA 185
            ....|:|.:|.::.:.|...|||.:||.|..::..:...|.:.......:...|.|.|||||:|.
Worm   140 EHATSIFLVGGMIVSPFVSQLSDILGRRPLFLIPLYISVAANLICAAAPNYLIFLLFRFISGVAT 204

  Fly   186 DTNFYLM-YIIVLEYIRPSMRTL----------GLNMAVGLFYCLGLVFTPWLAVLVGHWQIYLA 239
             |:|.:. :::.:|.:....|:|          |..|..|:||           |...:|::...
Worm   205 -TSFSMTGFVLCMESVSLEFRSLIPVLTTISWVGGYMLAGVFY-----------VFFKNWRVLYF 257

  Fly   240 CTSLPILLVVLYYFVVQESAQWLVTRNDIDGAIVR-LKRVAKFNGCRVSQADFDEFRRHCQMTHE 303
            ..|:|.||.:.:::...||..||:|:.: |..|.: :.....||...:|..|       |:....
Worm   258 AASVPGLLTIPFFWFTPESLHWLMTKQN-DRKIKKYINESVAFNKQTISLID-------CRNIQT 314

  Fly   304 MLGGDDKKQATLLDMFRT---PRMRKNTLILFFKSMVITLCYDAVSRNVEGMGISPFIMFSLSAL 365
            :   |:....|....||.   |::..:.:|..|..:|::..|.|:|.....:.......:.||.|
Worm   315 V---DNAPATTKTRTFRALFYPKIFVHVVINSFILIVMSGTYWALSLYSTELSEDETTGYFLSGL 376

  Fly   366 AVLPSSVLLVLLQDRIGRKGMASGSLLVGGLFTAAAGIAIAY--QQHNHNAILLACLTIAARFGV 428
            ..||:..|.|.|.....||.::..||    .|||...:...|  .|.|:..|    ..:.|:...
Worm   377 VELPAGFLSVFLLIAFKRKTVSFYSL----AFTAVFMLCTVYIPMQGNYKMI----FPLLAKSTN 433

  Fly   429 AISYESGSQYATELIPTCVRGQGVAAVHVAGFAASFLAPYILWLGTFFKAAPSIILGVLFFAGSF 493
            :|.:.|.....:|..||.:|......|...|...|..|||:..|....:.||:|::.::....:|
Worm   434 SIVWASQPLLYSEATPTTIRNVFSGVVSFVGELGSIGAPYMNRLTAINQDAPAILISIMSIVAAF 498

  Fly   494 VCLLLPETLNRSLPTTIEE---GEVFGKGERMFDFPCLHNKHDDEESESELEKYKRKHSLIDAKQ 555
            :.||.|||.|:.||..:::   |.:| :|.:         |..|.|:....|:.|.|...::..:
Worm   499 LVLLQPETKNKKLPEDLDQFDAGPLF-RGWK---------KQKDLEASEASEEVKEKEEAVELLE 553

  Fly   556 MQ 557
            ::
Worm   554 VK 555

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6231	NP_001262734.1	2A0119	11..509	CDD:273328	129/524 (25%)
CG6231	NP_001262734.1	MFS	125..499	CDD:119392	97/390 (25%)
C06H5.6	NP_507509.3	MFS_SLC22	115..504	CDD:340875	104/419 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010