DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6231 and Y82E9BR.16

DIOPT Version :9

Sequence 1:	NP_001262734.1	Gene:	CG6231 / 42339	FlyBaseID:	FBgn0038720	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_001022960.1	Gene:	Y82E9BR.16 / 175300	WormBaseID:	WBGene00022348	Length:	575	Species:	Caenorhabditis elegans

Alignment Length:	596	Identity:	148/596 - (24%)
Similarity:	253/596 - (42%)	Gaps:	125/596 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDFDQI----LAKCGDFNRYQFMILALFGFINIIVSMH--------------------------Y 35
            |.||..    |.:.|.:.:.||.::.|   ..|:||||                          |
Worm     1 MKFDDFLFTYLGEMGKYQKIQFFLVCL---PTIVVSMHALSWTFASVDTPYRCRLPSDLPEKEPY 62

  Fly    36 FTQTVISFVPDHWCYHDKLVNMTYKEIGEIYAQFENPSCTRLDDINGH-----NVTVSSKACEKW 95
            :| |:::|..   |.:|...|:...|.|:.........||..|:...|     :..|...|.::|
Worm    63 YT-TLLNFTK---CTNDADANVPISEYGKPGVTCHYDRCTLPDNETCHEHIFDHSKVEYTAVQRW 123

  Fly    96 IYNYDFGYRSMNTELNWVCDSAYKARIGQSLFFIGSVVGTLFYGLLSDKIGRVP----ALILSNF 156
                     .:..:.:|:     ||.| |:.:::|.:.|:..:|:|.|:|||..    |:::...
Worm   124 ---------EITCDRSWI-----KATI-QAAYYVGQMAGSTTFGMLGDRIGRKKVFFLAIVIQIT 173

  Fly   157 CGFAGDFSTIFTKSVATFTLCRFISGLAADTNFYLMYIIVLEYIRPSMRTLGLNMAVGLFYCLGL 221
            |.:....:..:.    .:.|.|..:|.:....|.:..:|.:|.:.|..|.|. ::..|||:.||.
Worm   174 CAYLIAIAPYWW----LYALARAGTGFSHPGIFVIAVVIGMELVGPKYRKLA-SVITGLFFALGQ 233

  Fly   222 VFTPWLAVLVGHWQIYLACTSLPILLVVLY--------------------------YF---VVQE 257
            :|....|:...::||.....:.|.||.:.|                          :|   :|.|
Worm   234 IFLGIEAIYFTNYQILHVVIASPALLFLSYCQKSAKNRKKIDFANFLADFLLKNRFFFSRWLVPE 298

  Fly   258 SAQWLVTRNDIDGAIVRLKRVAKFNGCRVSQADFDEFRRHCQMTHEMLGGD-----DKKQATLLD 317
            ||:|||::.....|...|::.|..||..:.:..::      |:.....||.     ..|:.|..|
Worm   299 SARWLVSQKRYKEADEVLQKAASVNGTVLPENWWE------QLDDSTTGGGGAPGAPTKKLTGAD 357

  Fly   318 MFRTPRMRKNTLILFFKSMVITLCYDAVSRNVEGMGISPFIMFSLSALAVLPSSVLLVLLQDRIG 382
            :||||.:||.||::||...||::.|..::.....:|...::.|..:|...:|:..::.||.||||
Worm   358 LFRTPELRKRTLVVFFLWPVISMVYYGMAMKANVLGGDIYVNFIFAAFVEIPALFIVYLLIDRIG 422

  Fly   383 RKGMASGSLLVGGLFTAAAGIAIAYQQHNHNAILLACLTIAARFG-VAISYESGSQYATELIPTC 446
            |:     .:|.||||.|.|.:.:.:...::..:.:|...:|...| :...|.:...|:.||.||.
Worm   423 RR-----LILAGGLFIAGACLLVNWLMGDNVQLWMAITQMAFTKGSITGVYAAIYTYSPELFPTV 482

  Fly   447 VRGQGV----AAVHVAGFAASFLAPYILWL----GTFFKAAPSIILGVLFFAGSFVCLLLPETLN 503
            :|...:    ....|...|||:::   :|:    |..|...|...:.||  |.....|.||||:.
Worm   483 IRNTAMGFCSTIARVGAIAASYIS---MWIAEQFGKVFMIIPFGCMAVL--AAVMTLLFLPETMG 542

  Fly   504 RSLPTTIEEGE 514
            :.||.:|||.|
Worm   543 KPLPESIEEIE 553

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6231	NP_001262734.1	2A0119	11..509	CDD:273328	140/575 (24%)
CG6231	NP_001262734.1	MFS	125..499	CDD:119392	104/420 (25%)
Y82E9BR.16	NP_001022960.1	MFS_SLC22	107..537	CDD:340875	112/465 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010