DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6231 and Ust5r

DIOPT Version :9

Sequence 1:	NP_001262734.1	Gene:	CG6231 / 42339	FlyBaseID:	FBgn0038720	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_599207.2	Gene:	Ust5r / 171398	RGDID:	620985	Length:	552	Species:	Rattus norvegicus

Alignment Length:	594	Identity:	136/594 - (22%)
Similarity:	249/594 - (41%)	Gaps:	102/594 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDFDQILAKCGDFNRYQFMILALFGFINIIVSMHYFTQTVISFVPDHWCYHDKLVNMTYKEIGEI 65
            |.|.::|.:.|...|:|.:.:|....||:.|..|...:...:.:|.|.|:...|.|:|   :.:.
  Rat     1 MAFQELLNQVGSLGRFQILQMAFVFLINVSVVPHSTIENFTAAIPSHRCWVPILDNVT---VSDN 62

  Fly    66 YAQFEN-----------------PSCTRLDDINGH----NVTVSS------KAC-EKWIYNYDFG 102
            :::..|                 ..|.|......|    |.|.||      :.| :.|:|:....
  Rat    63 HSRILNQDKLLKISIPLDSHLRLDKCRRFAQPQWHLLDLNDTFSSVTEADTEPCVDGWVYDRSNF 127

  Fly   103 YRSMNTELNWVCDSAYKARIGQSLFFIGSVVGTLFYGLLSDKIGR-------VPALILSNFC-GF 159
            :.:..||.:.||:|.....:.:..|.||:.:|.:..|.|||:.||       :..:.::..| ||
  Rat   128 HSTTVTEWDLVCESQVLNSVTKFSFMIGAFIGGIVNGPLSDRFGRKFVLKCALLQMAITETCVGF 192

  Fly   160 AGDFSTIFTKSVATFTLC--RFISGLA-----ADTNFYLM------YIIVLEYIRPSMRTLGLNM 211
            |.:|          |..|  ||::|:.     .::|..:.      ::.::..|.|...:.|..:
  Rat   193 ASNF----------FIYCSLRFLAGMTFEPILVNSNLLMFEWTSHKFLAMMSVIAPCAGSFGSMI 247

  Fly   212 AVGLFYCLGLVFTPWLAVLVGHWQIYLACTSLPILLVVLYYFVVQESAQWLVTRNDIDGAIVRLK 276
            ..||.:    .|..|     .|.|:.:   |:||...::....:.|||:||:..|.....:..|:
  Rat   248 LAGLAF----QFQNW-----HHLQLAM---SVPIFFFLILTRWLSESARWLIVTNKPQKGLKELR 300

  Fly   277 RVAKFNGCRVSQADFDEFRRHCQMTHEMLGGDDKKQATLLDMFRTPRMRKNTLILFFKSMVITLC 341
            :||..||.:.|..:.........|..|:...  |.:.:..|:|.||.:||....:.|..::..|.
  Rat   301 KVAHMNGMKNSGDNLTMEVVRTSMKRELEAA--KARPSPRDLFHTPILRKRICAMSFMRILFMLS 363

  Fly   342 YDAVSRNVEGMGISPFIM-FSLSALAVLPSSVLLVLLQDRIGRKGMASGSLLVGGLFTAAAGIAI 405
            ...:|.:::.:..:..:: |.:||.::| .||:...:.:|:||:......:.:.|:....|
  Rat   364 IFGMSLHLQHLSSNIMLLQFVVSASSLL-FSVIGPYVFNRMGRRITQMVVMTLRGICILTA---- 423

  Fly   406 AYQQHNHNAILLACLTIAARFGVAISYESGSQYATELIPTCVRGQGVAAVHVAGFAASFLAPYIL 470
            .:.......:.:..:|:|..|. |:|:.....:..||:||.:|...:..:.:.|.:..||||..:
  Rat   424 VFVPQEMQILRITVVTLAGAFS-ALSFGVNRLHTNELLPTTLRATAIGVIGMFGNSGFFLAPLFM 487

  Fly   471 WLGTFFKAAPSIILGVLFFAGSFVCLLLPETLNRSLPTTIEEGEVFGKGERMFDFPCLHNKHDD- 534
            .|.::....|.|..|.......|...|||||.|:.||                  .|:|:..:|
  Rat   488 ILASYSPNLPWIFYGGFSILNGFTVFLLPETKNQPLP------------------DCIHDIGNDW 534

  Fly   535 EESESELEK 543
            |||..|:::
  Rat   535 EESRQEMKE 543

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6231	NP_001262734.1	2A0119	11..509	CDD:273328	126/547 (23%)
CG6231	NP_001262734.1	MFS	125..499	CDD:119392	89/395 (23%)
Ust5r	NP_599207.2	MFS_OAT	109..516	CDD:340932	97/436 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347329
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.940