Protein Alignment CG6231 and SLC22A31

DIOPT Version :9

• Sequence 1: NP_001262734.1
• Gene: CG6231 / 42339
• FlyBaseID: FBgn0038720
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_001371692.1
• Gene: SLC22A31 / 146429
• HGNCID: 27091
• Length: 446
• Species: Homo sapiens
• Alignment Length: 425
• Identity: 113/425 - (26%)
• Similarity: 184/425 - (43%)
• Gaps: 42/425 - (9%)

  Fly   111 NW--VCDSAYKARIGQSLFFIGSVVGTLFYGLLSDKIGR----VPALILSNFCGFAGDFSTIFTK 169
            ||  ||...:|..:.|....:|.::|.:..|...|:.||    |.:|:|:...|    .|.....
Human     8 NWNLVCGDGWKVPLEQVSHLLGWLLGCVILGAGCDRFGRRAVFVASLVLTTGLG----ASEALAA 68

  Fly   170 SVATFTLCRFISGLAADTNFYLMYIIVLEYIRPSMRTLGLNMAVGLFYCLGLVFTPWLAVLVGHW 234
            |..|..:.|.:.|.........:|:..||...|..| |..:|..|||..:|.:..|.||.||..|
Human    69 SFPTLLVLRLLHGGTLAGALLALYLARLELCDPPHR-LAFSMGAGLFSVVGTLLLPGLAALVQDW 132

  Fly   235 QIYLACTSLPILLVVLYY---FVVQESAQWLVTRNDIDGAIVRLKRVAKFNGCRVSQADFDEFRR 296
            ::.....:|...|::|::   .:..||..||:....:..|...|.|.|:.:|.....:..:|...
Human   133 RLLQGLGALMSGLLLLFWGFPALFPESPCWLLATGQVARARKILWRFAEASGVGPGDSSLEENSL 197

  Fly   297 HCQMTHEMLGGDDKKQATLLDMFRTPRMRKNTLILFFKSMV---ITLCY-DAVSRNVEGMGISPF 357
            ..::|.........:..:.|.:.||....:|.|||.|.|:|   |...: .:::..|....:..|
Human   198 ATELTMLSARSPQPRYHSPLGLLRTRVTWRNGLILGFSSLVGGGIRASFRRSLAPQVPTFYLPYF 262

  Fly   358 IMFSLSALAVLPSSVLLVLLQDRIGRKGMASGSLLVGGLFTAAAGIAI---AYQQHNHNAILLAC 419
            :...|.|.|:    |.|:|..|..||:.:    ||:|.:.|..|.:.:   |........:.|:.
Human   263 LEAGLEAAAL----VFLLLTADCCGRRPV----LLLGTMVTGLASLLLLAGAQYLPGWTVLFLSV 319

  Fly   420 L-TIAARFGVAISYESGSQYATELIPTCVRGQGVAAVHVAGFAASFLAPYILW---LGTFFKAAP 480
            | .:|:|...|:|    |.:|.|:.||.:||.|:..|..|||......|....   .|.|.:...
Human   320 LGLLASRAVSALS----SLFAAEVFPTVIRGAGLGLVLGAGFLGQAAGPLDTLHGRQGFFLQQVV 380

  Fly   481 SIILGVLFFAGSFVC-LLLPETLNRSLPTTIEEGE 514
            ...|.||    :.:| |||||:.:|.||.::::.:
Human   381 FASLAVL----ALLCVLLLPESRSRGLPQSLQDAD 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6231	NP_001262734.1	2A0119	11..509	CDD:273328	113/418 (27%)
		MFS	125..499	CDD:119392	101/392 (26%)
SLC22A31	NP_001371692.1	MFS	9..383	CDD:421695	100/390 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153751
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.030