DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6231 and str-176

DIOPT Version :9

Sequence 1:	NP_001262734.1	Gene:	CG6231 / 42339	FlyBaseID:	FBgn0038720	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_001294210.1	Gene:	str-176 / 13197055	WormBaseID:	WBGene00006220	Length:	540	Species:	Caenorhabditis elegans

Alignment Length:	486	Identity:	112/486 - (23%)
Similarity:	207/486 - (42%)	Gaps:	92/486 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 ING-HNVTV---SSKACEKWIYNYDFGYRSMNTELNWVCDSAYKARIGQSLFFIGSVVGTLFYGL 140
            :|| |.:..   .:..||.   :..:.::|:..|.|::|:.|.|.:...::...|.:||...:|.
Worm    98 LNGCHELAAFRNETNLCEP---DLRYQFKSVQVEFNYICEDAKKVKNTITVQTFGVLVGAAIFGQ 159

  Fly   141 LSDKIGRVPALILSNFCGFAGDFSTIFTKSVATFTLCRFISGLAADTNFYLMYIIVLEYIRPSMR 205
            :||..||..||::|.......::.|.::..:..|.:.|.::|:.......:..:.::|.|....|
Worm   160 VSDTFGRRKALLISTLGNGLFNWITAYSPDLFYFMVWRTLAGVFTGGVTVVQMVFMVENIPRKDR 224

  Fly   206 TLGLNMAVGLFYCLGLVFTPWLAVLVGHWQ---IYLACTSLPILLVVLYYFVVQESAQWLVTRND 267
            ....|   .:.:...|:..|::|.|...|:   :.:|.:|:...|..|   :::||.:||:.:..
Worm   225 MWIQN---SITWSPNLILFPFVAWLCQDWRTMSVVIAASSIATFLACL---ILEESPRWLIQKGR 283

  Fly   268 IDGA---IVRLKRVAKFNGCRVSQADFDE-FRRHCQMTHEMLGGDDKKQATLLDMFRTPRMRKNT 328
            |:.|   ::|:::..|.         :|| |.:...   |:|..:.:|.|.     .:.:.:|.|
Worm   284 IEEARKSLIRIRKTDKL---------YDETFEKQLD---EVLHVEAEKHAR-----SSKKAKKYT 331

  Fly   329 LILFF---KSMVITLCYDAVSRNVEGMGISPFIMFSLS------------ALAVLPSSVLLVLLQ 378
            .|..|   |.:..:|.:      :.|:..:.||::||.            .||::.:|..::.:.
Worm   332 FIHLFCTWKMIAQSLTF------ITGITCTTFIVYSLMYNMEKLSGSLYWNLAIMGASRWIINIA 390

  Fly   379 DRI--------GRKGMASGSLLVGGLFTAAAGIAIAYQQHNHNAILLACLTIAARFGVAISYESG 435
            ..|        ||| |.:...::..|| |...||: |....:|..|:|..|:||....:..:.:.
Worm   391 VSIADYKLPWFGRK-MINQIAMICTLF-ALLMIAV-YLYFGYNGQLIAIGTVAAVSMCSQLFIAK 452

  Fly   436 SQYATELIPTCVRGQGVAAVHVAGFAASFLAPYILWLGTFFKAAPSIILGVLFFAGSFVC----- 495
            .....||.||.||...|:||.......|..:|.:.:|..:.:..|..:|        |.|
Worm   453 YMMVNELYPTAVRNLAVSAVSTMSRIGSMFSPQLFYLSDYAEWIPYAVL--------FSCQLYDF 509

  Fly   496 ----LLLPET----LNRSLPTTIEEGEVFGK 518
                |.||||    |...||.  :...:|||
Worm   510 IVLSLFLPETKGVILENHLPP--KHKRIFGK 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6231	NP_001262734.1	2A0119	11..509	CDD:273328	109/475 (23%)
CG6231	NP_001262734.1	MFS	125..499	CDD:119392	91/412 (22%)
str-176	NP_001294210.1	2A0119	13..527	CDD:273328	107/471 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162929
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.940