DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6231 and slc22a13

DIOPT Version :9

Sequence 1:	NP_001262734.1	Gene:	CG6231 / 42339	FlyBaseID:	FBgn0038720	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	XP_031760340.1	Gene:	slc22a13 / 100491580	XenbaseID:	XB-GENE-959647	Length:	547	Species:	Xenopus tropicalis

Alignment Length:	557	Identity:	137/557 - (24%)
Similarity:	232/557 - (41%)	Gaps:	64/557 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 DFDQILAKCGDFNRYQ---FMILALFGFINIIVSMHYFTQTVISFVPDHWCYHDK----LVNMTY 59
            ||.:||...|:|.|:|   .::|:|..|:|   :.|.|:|..:.....|.|  |.    |:|...
Frog     3 DFAEILKNVGEFGRFQKQLVVVLSLLSFLN---AFHMFSQVFMEIPVPHRC--DSRWILLINPNL 62

  Fly    60 KEIGEI--------YAQFE-----NPSCTRLDDINGHNVTVSSKACEKWIYNYDFGYRSMNTELN 111
            .|...:        ..|:|     :|....::.|....:..:....:.|.|:......::.|:.:
Frog    63 TEAERLNYTIPRDGRGQYEQCLMYSPVQWDMESIEKFGLNSTGPCQDGWEYDTSEQKSTLVTQFD 127

  Fly   112 WVCDSAYKARIGQSLFFIGSVVGTLFYGLLSDKIGRVPALILSNFCGFAGDFSTIFTKSVATFTL 176
            .||....:..|.||::..|.::|.|.:|.|.|:|||.|.::||.........|..|......:|.
Frog   128 LVCHRREQTGISQSVYMSGLLIGALLFGPLGDRIGRRPVILLSMLLQLVFGLSAAFAPHFYVYTA 192

  Fly   177 CRFISGLAADTNFYLMYIIVLEYIRPSMR-----TLGLNMAVGLFYCLGLVFTPWLAVLVGHWQI 236
            .|::.|.:.........::..|::..|.|     |..:..||||....|:.:.      :.:|::
Frog   193 FRWVVGTSMSGLMINNLVLGAEWVGSSRRACATITAHVCFAVGLMALAGVSYG------IRNWRL 251

  Fly   237 YLACTSLPILLVVLYYFVVQESAQWLVTRNDIDGAIVRLKRVAKFNGCRVSQADFDEFRRHCQMT 301
            ....:|.|..|:..|.:|:.|||:||:|:...:.|:..||:.|..|...:.:....:|...
Frog   252 LQIVSSAPTALLFFYIWVLPESARWLLTKGKKEKAVKLLKKAAAMNKKEIPEDLLFQFNEE---- 312

  Fly   302 HEMLGGDDKKQATLLDMFRTPRMRKNTLILFFKSMVITLCYDAVSRNVEGMGISPFIMFSLSALA 366
                  ...|...::|:||...:||.||::.....|.:|.|..:|.||...|:..::...:....
Frog   313 ------KSPKSGNMIDLFRNKTLRKLTLVMCLVWFVNSLVYYGLSLNVGSFGLDIYLTQLVFGAV 371

  Fly   367 VLPSSVLLVLLQDRIGRKGMASGSLLVGG----LFTAAAGIAIAYQQHNHNAILLACLTIAARFG 427
            .:|:.:..:......|||......|.:||    :.||..         .:..|.:..|.:..:|.
Frog   372 EIPARIGAMFAVQLFGRKPSQMFCLFLGGTVCLIITAIP---------RNLPIAITILAVIGKFS 427

  Fly   428 VAISYESGSQYATELIPTCVRGQGVAAVHVAGFAASFLAPYILWLGTFFKAAPSIILGVLFFAGS 492
            :|.|:.....||.|:.||.:|..||....:|...|...||.|..|..:..|.|..|.|.....|.
Frog   428 IASSFSICYIYAAEVFPTVIRQNGVGLASMAARVAGITAPLISLLDKYHAAIPMAIYGSGPIIGG 492

  Fly   493 FVCLLLPETLNRSLPTTIEEGEVFGK-----GERMFD 524
            .:|.|||||.|:.|....::.|....     |||:.:
Frog   493 ILCFLLPETRNKDLQDHTQQDEPIKSSNTLPGERLIN 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6231	NP_001262734.1	2A0119	11..509	CDD:273328	129/526 (25%)
CG6231	NP_001262734.1	MFS	125..499	CDD:119392	95/382 (25%)
slc22a13	XP_031760340.1	2A0119	12..509	CDD:273328	129/526 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010