DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6231 and LOC100490946

DIOPT Version :9

Sequence 1:	NP_001262734.1	Gene:	CG6231 / 42339	FlyBaseID:	FBgn0038720	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	XP_031756488.1	Gene:	LOC100490946 / 100490946	-ID:	-	Length:	517	Species:	Xenopus tropicalis

Alignment Length:	527	Identity:	136/527 - (25%)
Similarity:	228/527 - (43%)	Gaps:	57/527 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 ILAKCGDFNRYQFMILALFGFINIIVSMHYFTQTVISFVPDHWCYHDKLVNMTYKEIGEIYAQFE 70
            :|.|...|:.:|.:::.|.......|..|.|.....:.||.:.|..    |||..:     .::.
Frog     7 VLDKDSLFSPFQAIMVTLLSAPLCFVGTHNFMPVFAAAVPPYNCRS----NMTMDQ-----PRYP 62

  Fly    71 NPSCTRLDDINGHNVTVSSKACEK-WIYNYDFGYRSMNTELNWVCDSAYKARIGQSLFFIGSVVG 134
            ...||:...    :::.|:|.||: |.|::.....::.:|.:.|||......:.||::..|.:||
Frog    63 EDPCTQYVS----SLSNSTKPCEEGWEYDHSIFTSTIISEWDLVCDRQTLKEVAQSVYMAGVLVG 123

  Fly   135 TLFYGLLSDKIGRVPALILSNFCGFAG-DFSTIFTKSVATFTLCRFISGLAADTNFYLMYIIV-- 196
            ...||.|:|:.|| .|:||.:....|| ......:.::..:.|.||::|:.      :..:|:
Frog   124 AAVYGALADRFGR-RAMILCSLLQIAGMGIGVALSPNIIVYCLFRFLTGMG------ICGLIIND 181

  Fly   197 ----LEYIRPSMRTLGLNMAVGLFYCLGLVFTPWLAVLVGHWQIYLACTSLPILLVVLYYFVVQE 257
                :|:.....|.: ::|..|.....|.:....||..:..|:......|||..:..|....|.|
Frog   182 LGLAMEWTPRRYRPI-VSMIQGYGLTCGAIILVGLAYAIRGWRWLQLTASLPYFIFFLLMCWVPE 245

  Fly   258 SAQWLVTRNDIDGAIVRLKRVAKFNGCRVSQADFDEFRRHCQMTHEMLGGDDK-------KQATL 315
            ||:||..:...:.|:..|.||||.||.:...          .:|.|||..||:       .:.|.
Frog   246 SARWLSLKKHSNQALANLNRVAKINGRKEGG----------PITLEMLKLDDQHSTKAMTTKLTP 300

  Fly   316 LDMFRTPRMRKNTLILFFKSMVITLCYDAVSRNVEGMGISPFIMFSLSALAVLPSSVLLVLLQDR 380
            ||:||||.||..||||.......:..:.|::.:|:..|:|.::...:.|.:.||..:|..:....
Frog   301 LDLFRTPTMRTITLILSLSWFSSSFGFFAIALDVDRFGLSLYLTQGVFAGSELPIRILATITAFY 365

  Fly   381 IGRKGMASGSLLVGG---LFTAAAGIAIAYQQHNHNAILLACLTIAARFGVAISYESGSQYATEL 442
            |||:...|..|:..|   |.|.|.        .....:|...||:.|:..:.........|..|:
Frog   366 IGRRLTISFLLIFAGTLLLCTMAV--------PKDMLLLQMILTVLAKASLGSCIVCSYLYTAEV 422

  Fly   443 IPTCVRGQGVAAVHVAGFAASFLAPYILWLGTFFKAAPSIILGVLFFAGSFVCLLLPETLNRSLP 507
            .||.:|..|:...::.....:.::|.::....:....|.:|..|:........||||||||..|.
Frog   423 YPTVLRQTGLGFTNMMMRLGAIISPLVMITRVYVSFLPMVIFAVMPIISGLPILLLPETLNCPLM 487

  Fly   508 TTIEEGE 514
            .|:||.|
Frog   488 DTVEEVE 494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6231	NP_001262734.1	2A0119	11..509	CDD:273328	130/515 (25%)
CG6231	NP_001262734.1	MFS	125..499	CDD:119392	98/390 (25%)
LOC100490946	XP_031756488.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000