DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6231 and slc22a20p.1

DIOPT Version :9

Sequence 1:	NP_001262734.1	Gene:	CG6231 / 42339	FlyBaseID:	FBgn0038720	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	XP_004913725.1	Gene:	slc22a20p.1 / 100489586	XenbaseID:	XB-GENE-6463910	Length:	572	Species:	Xenopus tropicalis

Alignment Length:	557	Identity:	155/557 - (27%)
Similarity:	240/557 - (43%)	Gaps:	69/557 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDFDQILAKCGDFNRYQFMILALFGFINIIVSMHYFTQTVISFVPDHWCYHDKLVNMTYKEIGEI 65
            |.|:.:|...|...|:|.:...:.....:.:..|.|.|...:.||.|.|:...|.|.|   :|
Frog     1 MGFNDLLLSVGGLGRFQIIHTTMLLIPMLFMGCHNFLQNFSAAVPAHRCWVPSLDNNT---MG-- 60

  Fly    66 YAQFENPSCTRLDD------------------INGHNVTVSSKACEK-WIYNYDFGYRSMNTELN 111
            |.|...|:...:|:                  .||.: |..::.||. |:|:......::.||.:
Frog    61 YDQDHLPAFIPMDESEKPLSCLRYRKALHSMWTNGTS-TNHTEPCEDGWVYDKSDFSSTIVTEWD 124

  Fly   112 WVCDSAYKARIGQSLFFIGSVVGTLFYGLLSDKIGRVPALILSNF----CGFAGDFSTIFTKSVA 172
            .||......:|.||::..|.:||.:..|.|||::||...||.||.    ||....|...|
Frog   125 LVCKLRKMRQIAQSIYMAGVLVGAVLLGGLSDRLGRRALLIGSNLVMAVCGTCAAFLPNF----- 184

  Fly   173 TFTLCRF-------ISGLAADTNFYLMYIIVLEYIRPSMRT-LGLNMAVGLFYCLGLVFTPWLAV 229
             .|.|.|       .||:..:||     .::||:..|..|| :|...|.| |.| |.:....||.
Frog   185 -ITYCTFRCLCGIAFSGITLNTN-----SLILEWTPPKGRTIMGTLFAAG-FTC-GQILLAALAY 241

  Fly   230 LVGHWQIYLACTSLPILLVVLYYFVVQESAQWLVTRNDIDGAIVRLKRVAKFNGCRVSQADFDEF 294
            .:..|:......|.|.....||.::|.|||:||:.:.....|:..|:|||..||.|.......|.
Frog   242 GIREWRWLQFAVSAPFYFFFLYSWLVPESARWLILKGRSHEALKALQRVAIINGKREEGQKLSEM 306

  Fly   295 RRHCQMTHEMLGGDDKKQATLLDMFRTPRMRKNTLILFFKSMVITLCYDAVSRNVEGMGISPFIM 359
            .....|..|:  ...|:..:|.|:||||.|||.|:.|........:.:..:..:::..|||.|::
Frog   307 ILISHMQSEL--NQVKRPHSLFDLFRTPGMRKVTICLMMVWFSSGVAFYGLGMDLQNFGISIFLL 369

  Fly   360 -FSLSALAVLPSSVLLVLLQDRIGRKGMASGSLLVGG--LFTAA---AGIAIAYQQHNHNAILLA 418
             |:..|:. :|:.|:..||...:||:...:..|::.|  |.|.|   .|:          .||..
Frog   370 QFTFGAID-MPAKVVAALLMTYMGRRVTQATVLILSGVALLTNAFIPQGM----------KILRM 423

  Fly   419 CLTIAARFGVAISYESGSQYATELIPTCVRGQGVAAVHVAGFAASFLAPYILWLGTFFKAAPSII 483
            .|.:..:..:|.|:.....::.||.||.:|..|:..|.:.....|.:||.:|.|.......||.|
Frog   424 VLAVFGKGCMAASFACAYLFSGELFPTVIRQTGMGVVAMMARVGSVVAPLVLLLWEISPILPSAI 488

  Fly   484 LGVLFFAGSFVCLLLPETLNRSLPTTIEEGEVFGKGE 520
            .|:...........|.||.|:.||.::||.|...:|:
Frog   489 YGIAAIIAGGAATFLMETNNQQLPESVEEVEARSQGK 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6231	NP_001262734.1	2A0119	11..509	CDD:273328	148/534 (28%)
CG6231	NP_001262734.1	MFS	125..499	CDD:119392	111/391 (28%)
slc22a20p.1	XP_004913725.1	MFS	101..485	CDD:391944	117/409 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000