DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6231 and slc22a7b.3

DIOPT Version :9

Sequence 1:	NP_001262734.1	Gene:	CG6231 / 42339	FlyBaseID:	FBgn0038720	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	XP_001337264.3	Gene:	slc22a7b.3 / 100001772	ZFINID:	ZDB-GENE-131120-103	Length:	546	Species:	Danio rerio

Alignment Length:	587	Identity:	151/587 - (25%)
Similarity:	263/587 - (44%)	Gaps:	97/587 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDFDQILAKCGDFNRYQFMILALFGFINIIVSMHYFTQTVISFVPDHWC---YHDK--------- 53
            |.|:.::.:...|.|:|.|||.:......|:..|:.....|:.:|.|.|   :.|.
Zfish     1 MKFEDLITEINGFGRFQKMILCISFVGRFIIPCHFLLSNFIAAIPSHHCDISFLDADGLFGNLTE 65

  Fly    54 ----LVNMTYKEIGEIYA--QFENPSCTRLDDINGHNVTVSSKA------CEK-WIYNYDFGYRS 105
                :|::..:|.|...:  .|.:|....|       :..||.:      |:. |.::......:
Zfish    66 EERLIVSVPTQEDGSPVSCHMFSHPQFQLL-------INSSSSSDLPVVECQNGWHFDNSTFIST 123

  Fly   106 MNTELNWVCDSAYKARIGQSLFFIGSVVGTLFYGLLSDKIGRVPALILSNFCGFAGDFSTIFTKS 170
            :.|:.:.|||:....:...::||:|.:.|..|:|.:||:.||.|.|::|...|.|...:::|:.|
Zfish   124 LATQWDLVCDNRGLNKAVATIFFVGVMFGAAFFGGMSDRFGRKPMLLVSYISGMAFALASVFSTS 188

  Fly   171 VATFTLCRFISGLAADTNFYLMYIIVLEYIRPSMRTLGLNMAVGLFYCLGLVFTPWLAVLVGHWQ 235
            ...|.:.||.||........:..::.||::....|.| :::...:.:.:|......:|..:..|:
Zfish   189 FTMFAVLRFFSGFTITGIVIVSSVLNLEWVDIEHRRL-VSIIDSMAWAVGSTSLALIAYFIRDWR 252

  Fly   236 IYLACTSLPILLVVLYYFVVQESAQWLVTRNDIDGAIVRLKRVAKFNGCRVSQADFDEFRRHCQM 300
            ......:.|::|..:.::.|.|||:||:...|::.|...|.:.|..|             |..::
Zfish   253 WLTVAVTSPLVLCTILWWWVPESARWLIANGDVEKAHYYLHKCAVMN-------------RKAEV 304

  Fly   301 THEM--------LGGDDKKQATLLDMFRTPRMRKNTLI---LFFKSMVITLCYDAVSRNVEGMGI 354
            |..:        :....||:.|.||:.|||:|||..::   ::|  .|.|:.| .:|.|:.|.|:
Zfish   305 TSRIKPEALAISVSDQGKKKYTYLDLVRTPKMRKLAMLTGTVWF--CVATMTY-GISLNITGFGL 366

  Fly   355 SPFI-MFSLSALAVLPSSVLLVLLQDRIGRKGMASGSLLVGGLFTAAAGIAIAYQQ---HNHNAI 415
            :.:: .|...|:.| ||.:::..|.::|||:...:|:.|..|: :....|.|...|   ....|:
Zfish   367 NMYLTQFVYGAIEV-PSKLIVYYLLEKIGRRKTEAGAQLFAGI-SLMINIFIPKDQWIGRTVVAV 429

  Fly   416 LLACLTIAARFGVAISYESGSQYATELIPTCVRGQGVAAVHVAGFAASFL-------APYILWLG 473
            |.....:||...:.:       |::||.||.:|..|:      |: .|||       ||.:|.|.
Zfish   430 LGKGFAVAAFCTIVL-------YSSELYPTVLRQNGM------GY-NSFLARLGVSVAPLVLLLD 480

  Fly   474 TFFKAAPSIILGVLFFAGSFVCLLLPETLNRSLPTTIEEGEVFGKGERMFDFPCLHNKHDDEESE 538
            ||:......||..:....|.|...||||.:|.||.|||:.|..||         ..|| |.|:.|
Zfish   481 TFWGQFSQTILCSVALIASVVAWNLPETRDRCLPETIEDVEGTGK---------TPNK-DQEKQE 535

  Fly   539 SE 540
            :|
Zfish   536 NE 537

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6231	NP_001262734.1	2A0119	11..509	CDD:273328	137/544 (25%)
CG6231	NP_001262734.1	MFS	125..499	CDD:119392	103/395 (26%)
slc22a7b.3	XP_001337264.3	2A0119	12..516	CDD:273328	137/543 (25%)
slc22a7b.3	XP_001337264.3	MFS	141..506	CDD:119392	103/397 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588981
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D284622at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.950