DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6231 and zmp:0000001102

DIOPT Version :9

Sequence 1:	NP_001262734.1	Gene:	CG6231 / 42339	FlyBaseID:	FBgn0038720	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	XP_001340340.6	Gene:	zmp:0000001102 / 100000058	ZFINID:	ZDB-GENE-140106-62	Length:	560	Species:	Danio rerio

Alignment Length:	558	Identity:	147/558 - (26%)
Similarity:	252/558 - (45%)	Gaps:	81/558 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDFDQILAKCGDFNRYQFMILALFGFINIIVSMHYFTQTVISFVPDHWC-----YHDKLVNMTYK 60
            |.||.||.:...|.|||..::.|.....|.:..|:.....|:.:|.|.|     ..|.|.|:|.|
Zfish    11 MKFDNILDETDGFGRYQIALVMLLFIPRITIPCHFLLNNFIAAIPSHHCDISSLDADGLGNLTQK 75

  Fly    61 E--IGEIYAQ----------FENPSCTRLDDINGHNVTVSSKA-----CEK-WIYNYDFGYRSMN 107
            |  |..:.||          |.:|....|  ||    :.||.|     |:. |.::......::.
Zfish    76 ERLIVSVPAQEDGTPASCHMFAHPQFQLL--IN----SSSSSALPVVECQNGWHFDNSTFISTLA 134

  Fly   108 TELNWVCDSAYKARIGQSLFFIGSVVGTLFYGLLSDKIGRVPALILSNFCGFAGDFSTIFTKSVA 172
            |:.:.|||....|:...::||:|.:.|.:|:|:|.||.||...|::|.........::.|:.|..
Zfish   135 TQFDLVCDKRGLAKASATIFFVGVMCGAVFFGVLCDKYGRRSMLLVSYVFSIVFSVTSAFSSSYI 199

  Fly   173 TFTLCRFISGLAADTNFYLMYIIVLEYIRPSMRTLGLNMAVGLF----YCLGLVFTPWLAVLVGH 233
            .|...||::|||......:..::.:|::....||.     :|||    :.:|.:.....|.:|..
Zfish   200 MFAAFRFLTGLALTGISNISVVLSIEWVDTKHRTF-----MGLFGSMSWSIGNMLLAGFAFMVTD 259

  Fly   234 WQIYLACTSLPILLVVLYYFVVQESAQWLVTRNDIDGAIVRLKRVAKFNGCRVSQADFDEFRRHC 298
            |::.:...:.|:.|....::.:.:||:||:.....:.|...|.:.|.||    .:.||.. |...
Zfish   260 WRLLIVIVTAPLFLATATWWWIPDSARWLIANGKTETAYKYLHKCATFN----KRLDFTS-RVKP 319

  Fly   299 QMTHEMLGGDDKKQA-TLLDMFRTPRMRKNTLILFFKSMV---ITLCYDAVSRNVEGMGISPFIM 359
            :....::..|.:..: |.||:.:||::||.||   |..:|   :...|..:|.|:.|.|:.|::.
Zfish   320 ETLSTVVTVDHRGHSYTYLDLVKTPQLRKLTL---FTGIVWYGVASTYYGISLNITGFGLDPYLT 381

  Fly   360 FSLSALAVLPSSVLLVLLQDRIGRKGMASGSLLVGGLFTAAAGIAIAYQQHNHNAILLACL---- 420
            ..:.|...:|:.:|:....:::||:...:|:|::.|.                 .||:..:
Zfish   382 HFIYAAIEVPAKILVYFSLNKVGRRNTQTGTLVLTGF-----------------CILINIITPTE 429

  Fly   421 -----TIAARFGVAISYESGSQ---YATELIPTCVRGQGVAAVHVAGFAASFLAPYILWLGTFFK 477
                 |:.|..|..:|..|.:.   |.|||.||.:|..|:...:......:.::|.|:.|...:|
Zfish   430 YWTFRTVIAVLGKGLSEASFTTVILYTTELYPTVMRQNGLGFTNFMARMGASISPLIMLLEDIWK 494

  Fly   478 AAPSIIL-GVLFFAGSFVCLLLPETLNRSLPTTIEEGE 514
            ..|.:|. .:..|.| .:.||||||.|.|||.|:|:.|
Zfish   495 LLPEVIFCSMAIFCG-IIALLLPETNNASLPETVEDIE 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6231	NP_001262734.1	2A0119	11..509	CDD:273328	139/541 (26%)
CG6231	NP_001262734.1	MFS	125..499	CDD:119392	96/394 (24%)
zmp:0000001102	XP_001340340.6	Sugar_tr	22..526	CDD:331684	139/540 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D284622at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010