Protein Alignment CG16727 and Slc22a4

DIOPT Version :10

• Sequence 1: NP_650818.1
• Gene: CG16727 / 42338
• FlyBaseID: FBgn0038719
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_071606.1
• Gene: Slc22a4 / 64037
• RGDID: 621149
• Length: 553
• Species: Rattus norvegicus
• Alignment Length: 570
• Identity: 153/570 - (26%)
• Similarity: 252/570 - (44%)
• Gaps: 54/570 - (9%)

  Fly     2 DFDRVLEKCGNFGRFQFVILILYGYTNILSSLHYFSQTLITFTPEHWCSHDDLMGLGAAELRSIY 66
            |:|.|:...|::|.||.:|..|...:.|.:..:..|...:..||||.|.....:.|.:|     :
  Rat     3 DYDEVIAFLGDWGPFQRLIFFLLSASIIPNGFNGMSVVFLAGTPEHRCLVPHTVNLSSA-----W 62

  Fly    67 SNVSHP-----------SCT--LLSEVINGTGVASE------------ESCQD-WIFERENGYES 105
            .|.|.|           ||.  .|:.:.|.:.:..|            |||.| |.:.::....:
  Rat    63 RNHSIPLETKDGRQVPQSCRRYRLATIANFSALGLEPGLDVDLEQLEQESCLDGWEYSKDVFLST 127

  Fly   106 LTTELKWVCDKSHQPAVGQSFFFLGSVVGTISFGFLSDHIGRLPAMLMAALSGATG-DFITSFVH 169
            :.||...||:...:..:..|.||:|.:.|:...|.|||..|| ..:|.|.::..|| .|:..|..
  Rat   128 IVTEWNLVCEDDWKTPLTTSLFFVGVLCGSFVSGQLSDRFGR-KKVLFATMAVQTGFSFVQIFST 191

  Fly   170 TLPWFAFSRFVSGLSTDTMYYLMYILVFEYLSPKRRTFGLNIILAVFYCFGLMTSPWIAMWIGNW 234
            ....|.....:.|:...:.|.:.:||..|.||...|.....:.:..|:..|.|..|..|.:|.:|
  Rat   192 NWEMFTVLFAIVGMGQISNYVVAFILGTEILSKSVRILFSTLGVCTFFAIGYMVLPLFAYFIRDW 256

  Fly   235 RRYLWLASLPALGVLIYPL--LICESAQWLLTKKKYDEAVACLKKVAKFNGRQVEDSVFDEFVKH 297
            |..|...:||  |:...||  .|.||.:||:::::::||...::|.||.||......:||..
  Rat   257 RMLLLALTLP--GLFCVPLWWFIPESPRWLISQRRFEEAEQIIQKAAKMNGIMAPAVIFDPL--- 316

  Fly   298 YREKMNEESKLNKQMDTFLGMFKTPRLRRFTTTLLVKSVIITLSYDVINRNMEGLGSSPFKLFSL 362
               ::.|.:.|.:|....|.:|||..:...|...::..::.::.|..::.|:..|....:....|
  Rat   317 ---ELQELNSLKQQKVFILDLFKTRNIATITVMSVMLWMLTSVGYFALSLNVPNLHGDVYLNCFL 378

  Fly   363 TSSVYLPAGFTILLLQNKIGRKGMACGALLVGAIITAVTGFLIAVLDPSENAVLLALMVGLGRFG 427
            :..:.:||.||..||...:.|:.:..|.|..|..:.    .|:.|:....|.|.:.|:: ||:||
  Rat   379 SGLIEVPAYFTAWLLLRTLPRRYIIAGVLFWGGGVL----LLVQVVPEDYNFVSIGLVM-LGKFG 438

  Fly   428 TTVSYDAEIQYAAEIIPTSVRGQAVSNIHVVGLASSSLAFYVIYLAQYYKPLPSIFISVLMFLGA 492
            .|.::.....:.||:.||.||..||....:.....|.:|.|.:||..|.:.||.|.:..|..|..
  Rat   439 VTSAFSMLYVFTAELYPTLVRNMAVGITSMASRVGSIIAPYFVYLGAYNRLLPYILMGSLTVLIG 503

  Fly   493 LLCLTLPETLHKKLPETLADGERFAMNESCLYFPCLHKRRESLTEHEDRK 542
            ::.|..||:....|||.|...::..      .|.|..|...|:...|:.|
  Rat   504 IITLFFPESFGVTLPENLEQMQKVR------GFRCGKKSTVSMDREENPK 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16727	NP_650818.1	2A0119	11..509	CDD:273328	142/526 (27%)
Slc22a4	NP_071606.1	2A0119	12..519	CDD:273328	141/525 (27%)