Protein Alignment CG16727 and Slc22a27

DIOPT Version :10

• Sequence 1: NP_650818.1
• Gene: CG16727 / 42338
• FlyBaseID: FBgn0038719
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: XP_017173565.1
• Gene: Slc22a27 / 171405
• MGIID: 3042283
• Length: 576
• Species: Mus musculus
• Alignment Length: 557
• Identity: 139/557 - (24%)
• Similarity: 225/557 - (40%)
• Gaps: 74/557 - (13%)

  Fly     1 MDFDRVLEKCGNFGRFQFVILILYGYTNILSSLHYFSQTLITFTPEHWC---------------- 49
            |.|..:|.:.|:.||||.:.::.....|.:...|...:......|.|.|
Mouse    26 MSFQELLNQVGSLGRFQILQIVFLLLLNAIVVPHIAMENFTAAIPNHRCWVPILDNDTASDNGSR 90

  Fly    50 --SHDDLMGLG---------------------AAELRSIYSNVSHPSCTLLSEVINGTGVASEES 91
              |.|||:.:.                     ...|...:||||.|               ..|.
Mouse    91 ILSQDDLLRISIPLDSNLRPEKCRRFAQPQWHLLHLNGTFSNVSEP---------------DTEP 140

  Fly    92 CQD-WIFERENGYESLTTELKWVCDKSHQPAVGQSFFFLGSVVGTISFGFLSDHIGRLPAMLMAA 155
            |.| |:::|.|...::.||...||:.....:|.:..|.:|..:|.|..|.|||.:||...:..|.
Mouse   141 CVDGWVYDRSNFLSTIVTEWDLVCESQALNSVTKFSFMIGLFIGGIICGHLSDRLGRKFILTCAL 205

  Fly   156 LSGATGDFITSFVHTLPWFAFSRFVSGLSTDTMYYLMYILVFEYLSPKRRTFGLNIILAVFYC-- 218
            |..|..:...:|..:...:...||::|||.:.:....::|:.|:.|||    .|.::.|:..|
Mouse   206 LQFAITETCVAFAPSFFIYCSLRFLAGLSVEPILVNSHLLMLEWTSPK----FLTMMAALLSCAP 266

  Fly   219 -FGLMTSPWIAMWIGNWRRYLWLASLPALGVLIYPLLICESAQWLLTKKKYDEAVACLKKVAKFN 282
             .|.|.|..:|.....|.......|:|....||....:.|||:||:...|..:.:..|:|||..|
Mouse   267 NIGYMISAGLAFLFRIWHHLQLTMSVPIFFFLILTRWLSESARWLIVTNKPQKGLKELRKVAHMN 331

  Fly   283 GRQVEDSVFDEFVKHYREKMNEESKLNKQMDTFLGMFKTPRLRRFTTTLLVKSVIITLSYDVINR 347
            |.:....:..|.|   |..|..|.:..|...:...:|.|..||:....|....:..|:|...:..
Mouse   332 GMKNSGDLTMEIV---RTSMKAELEAAKTKPSLRDLFHTSILRKRICVLSFMRLFFTVSIFGLAV 393

  Fly   348 NMEGLGSSPFKLFSLTSSVYLPAGFTILLLQNKIGRKGMACGALLVGAIITAVTG--FLIAVLDP 410
            :::.|.|:...|..|.|::.:........:.|.|||:       :...::.::.|  .||||..|
Mouse   394 HLQHLSSNIILLQFLISALAILVSVIGPFVLNHIGRR-------ITYLVLMSLRGIFILIAVFVP 451

  Fly   411 SENAVLLALMVGLGRFGTTVSYDAEIQYAAEIIPTSVRGQAVSNIHVVGLASSSLAFYVIYLAQY 475
            .|...|..:|..|....:::.......:..|::||::|..||..|...|.:.|.|:...:.||.|
Mouse   452 QEMQTLRIIMATLAEGISSLCVGVSRLHTNELLPTTLRATAVGVIGFFGNSGSFLSPLFMLLATY 516

  Fly   476 YKPLPSIFISVLMFLGALLCLTLPETLHKKLPETLAD 512
            |..:|.||........|.....||||.::.||::..|
Mouse   517 YANMPWIFYGGFSIFNAFTVFLLPETKNQPLPDSTHD 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16727	NP_650818.1	2A0119	11..509	CDD:273328	135/542 (25%)
Slc22a27	XP_017173565.1	MFS_OAT	134..540	CDD:340932	111/434 (26%)