Protein Alignment CG16727 and SVOPL

DIOPT Version :10

• Sequence 1: NP_650818.1
• Gene: CG16727 / 42338
• FlyBaseID: FBgn0038719
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_001132928.1
• Gene: SVOPL / 136306
• HGNCID: 27034
• Length: 492
• Species: Homo sapiens
• Alignment Length: 571
• Identity: 139/571 - (24%)
• Similarity: 212/571 - (37%)
• Gaps: 198/571 - (34%)

  Fly    13 FGRFQFVILILYGYTNILSSLHYFSQTLITFTPEHWCSHDDLMGLGAAELRSIYSNVSHPSCTLL 77
            ||||...:.::.|.|.::.                           |.|:..|         .::
Human    43 FGRFHIALFLIMGSTGVVE---------------------------AMEIMLI---------AVV 71

  Fly    78 SEVINGTGVASEESCQDWIFERENGYESLTTELKWVCDKSHQPAVGQSFFFLGSVVGTISFGFLS 142
            |.||.         | :|..|            .|      |.|:..:..|.|.:|.:|.||.|:
Human    72 SPVIR---------C-EWQLE------------NW------QVALVTTMVFFGYMVFSILFGLLA 108

  Fly   143 DHIGRLPAMLMAALSGATGDFITSFVHTLPWFAFSRF-----VSGLSTDTMYYLMYILVFEYLSP 202
            |..||...:|::.|.||....:|||..:..||.|.|.     |||.|..      .|:..|:|..
Human   109 DRYGRWKILLISFLWGAYFSLLTSFAPSYIWFVFLRTMVGCGVSGHSQG------LIIKTEFLPT 167

  Fly   203 KRRTFGLNIILAVFYCFGLM----TSPWIAMWIGNWRRYLWLASLPALGVLIYPLLICESAQWLL 263
            |.|.:.|. :..||:..|.:    .:..|...|| ||..:.:||:|.:.:::....|.|||::.:
Human   168 KYRGYMLP-LSQVFWLAGSLLIIGLASVIIPTIG-WRWLIRVASIPGIILIVAFKFIPESARFNV 230

  Fly   264 TKKKYDEAVACLKKVAKFNGRQVEDSVFDEFVKHYREKMNE----ESKLNKQMDTFLGMFKTPRL 324
            :......|:|.|::|||.|                |..|.|    |..|.|: ..|..:.....|
Human   231 STGNTRAALATLERVAKMN----------------RSVMPEGKLVEPVLEKR-GRFADLLDAKYL 278

  Fly   325 RRFTTTLLVKSVIITLS---YDVINRNMEGL------GSSPFKLFSLTSS------------VYL 368
            |   |||.:..:.:.:|   |.||..:.|.|      ||.......:|..            ::.
Human   279 R---TTLQIWVIWLGISFAYYGVILASAELLERDLVCGSKSDSAVVVTGGDSGESQSPCYCHMFA 340

  Fly   369 PAGFTILLLQ---------------NKIGRK-----GMACGAL--LVGAIITAVTGFLIAVLDPS 411
            |:.:..:::.               |.:||:     .|.|.||  |:..|.|:..| ||..|
Human   341 PSDYRTMIISTIGEIALNPLNILGINFLGRRLSLSITMGCTALFFLLLNICTSSAG-LIGFL--- 401

  Fly   412 ENAVLLALMVGLGRFGTTVSYDAEIQYAAEIIPTSVRGQAVSNIHVVGLASS-SLAFYVIYLAQY 475
              .:|.||:        ..:::....|.||:.||::|        .:|:.:| ||......:|.
Human   402 --FMLRALV--------AANFNTVYIYTAEVYPTTMR--------ALGMGTSGSLCRIGAMVAP- 447

  Fly   476 YKPLPSIFIS-VLM---FLGALLCL-------------TLP-ETLHKKLPE 508
                   ||| |||   .||| |||             ||| ||..:.|.:
Human   448 -------FISQVLMSASILGA-LCLFSSVCVVCAISAFTLPIETKGRALQQ 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16727	NP_650818.1	2A0119	11..509	CDD:273328	139/571 (24%)
SVOPL	NP_001132928.1	MFS_SVOPL	49..480	CDD:341000	130/553 (24%)