Protein Alignment CG16727 and SLC22A9

DIOPT Version :10

• Sequence 1: NP_650818.1
• Gene: CG16727 / 42338
• FlyBaseID: FBgn0038719
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_543142.2
• Gene: SLC22A9 / 114571
• HGNCID: 16261
• Length: 553
• Species: Homo sapiens
• Alignment Length: 580
• Identity: 136/580 - (23%)
• Similarity: 239/580 - (41%)
• Gaps: 69/580 - (11%)

  Fly     1 MDFDRVLEKCGNFGRFQFVILILYGYTNILSSLHYFSQTLITFTPEHWC----------SHDDLM 55
            |.|..:|...|:..|||.:..:......:.:.||:..:....|.|.|.|          |.:|..
Human     1 MAFQDLLGHAGDLWRFQILQTVFLSIFAVATYLHFMLENFTAFIPGHRCWVHILDNDTVSDNDTG 65

  Fly    56 GLGAAELRSIY----SNVS--------HPSCTLLSEVING----TGVASEESCQD-WIFERENGY 103
            .|....|..|.    ||:.        ||...||.  :||    |..|..|.|.| |:::|.:..
Human    66 ALSQDALLRISIPLDSNMRPEKCRRFVHPQWQLLH--LNGTFPNTSDADMEPCVDGWVYDRISFS 128

  Fly   104 ESLTTELKWVCDKSHQPAVGQSFFFLGSVVGTISFGFLSDHIGRLPAM----LMAALSGATGDFI 164
            .::.||...|||.....:|.:..|..|.:||.|..|.|||..||...:    |..|:.|......
Human   129 STIVTEWDLVCDSQSLTSVAKFVFMAGMMVGGILGGHLSDRFGRRFVLRWCYLQVAIVGTCAALA 193

  Fly   165 TSFVHTLPWFAFSRFVSGLSTDTMYYLMYILVFEYLSPKRRTFGLNIILAVFYC---FGLMTSPW 226
            .:|:    .:...||:||::..::.....:|:.|:.:.:.:..|:.:.:    |   ...||...
Human   194 PTFL----IYCSLRFLSGIAAMSLITNTIMLIAEWATHRFQAMGITLGM----CPSGIAFMTLAG 250

  Fly   227 IAMWIGNWRRYLWLASLPALGVLIYPLLICESAQWLLTKKKYDEAVACLKKVAKFNG-RQVEDSV 290
            :|..|.:|.....:.|:|...:.:....:.|||:||:...|.:|.:..|:|.|..:| :...|::
Human   251 LAFAIRDWHILQLVVSVPYFVIFLTSSWLLESARWLIINNKPEEGLKELRKAAHRSGMKNARDTL 315

  Fly   291 FDEFVKHYREKMNEESKLNKQMDTFLGMFKTPRLRRFTTTLLVKSVIITLSYDVINRNMEGLGSS 355
            ..|.:|...:|..|.::  |:..:...|...|.:.:..:.|........::|..:|.:::.||::
Human   316 TLEILKSTMKKELEAAQ--KKKPSLCEMLHMPNICKRISLLSFTRFANFMAYFGLNLHVQHLGNN 378

  Fly   356 PFKLFSLTSSVYLPAGFTILLLQNKIGRKGMACGALLVGAIITAVTGFLIAVLDPSENAVLLALM 420
            .|.|.:|..:|.|.|..........:.|:......:.:.||.     .|..:..|.|...|..::
Human   379 VFLLQTLFGAVILLANCVAPWALKYMNRRASQMLLMFLLAIC-----LLAIIFVPQEMQTLREVL 438

  Fly   421 VGLGRFGTTVSYDAEIQYAAEIIPTSVRGQAVSNIHVVGLASSSLAFYVIYLAQYYKPLPSIFIS 485
            ..||...:.::......:..|:|||.:|.:|:.........:.:||..::.|:.|..|||.|...
Human   439 ATLGLGASALANTLAFAHGNEVIPTIIRARAMGINATFANIAGALAPLMMILSVYSPPLPWIIYG 503

  Fly   486 VLMFLGALLCLTLPETLHKKLPETLADGERFAMNESCLYFPCLHKRRESLTEHEDRKSEP 545
            |..|:.....|.||||.:|.|.:|:.|                 ::.|.....|.::.:|
Human   504 VFPFISGFAFLLLPETRNKPLFDTIQD-----------------EKNERKDPREPKQEDP 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16727	NP_650818.1	2A0119	11..509	CDD:273328	128/532 (24%)
SLC22A9	NP_543142.2	MFS_OAT	109..517	CDD:340932	98/422 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	528..553		4/36 (11%)