Protein Alignment CG17752 and SLC22A13

DIOPT Version :10

• Sequence 1: NP_650817.1
• Gene: CG17752 / 42337
• FlyBaseID: FBgn0038718
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_004247.2
• Gene: SLC22A13 / 9390
• HGNCID: 8494
• Length: 551
• Species: Homo sapiens
• Alignment Length: 540
• Identity: 145/540 - (26%)
• Similarity: 243/540 - (45%)
• Gaps: 69/540 - (12%)

  Fly     5 RVLEKCGNFGPYQILLLGLYGYTNIVSSLHYFSQTLISFTPSHRCS-APVEE--FSQNFTELLSC 66
            :||.:.|:||.:||.||.|....|.:|..::|:...:.....|.|: |.|:.  |:.:..|.|..
Human     6 QVLAEIGDFGRFQIQLLILLCVLNFLSPFYFFAHVFMVLDEPHHCAVAWVKNHTFNLSAAEQLVL 70

  Fly    67 SV----------------------IQYDVDMTSFRDNK---CS-SWDFDKESNYESITTELEWVC 105
            ||                      :|   |:.|.|.|:   |. .|:: .|:...|:..|...||
Human    71 SVPLDTAGHPEPCLMFRPPPANASLQ---DILSHRFNETQPCDMGWEY-PENRLPSLKNEFNLVC 131

  Fly   106 DDAYKLAVGQSFFFIGSALGSIFFGYLADRIGR----LPACVLSTLTGASGDFFTSFVGSLPMFS 166
            |..:.....||.|..|..:|::.||.|.|||||    |...:|.||.|.:    |:||.|..::.
Human   132 DRKHLKDTTQSVFMAGLLVGTLMFGPLCDRIGRKATILAQLLLFTLIGLA----TAFVPSFELYM 192

  Fly   167 FTRF-----ISGLSMDTQYVLMYILVFEYLSPQHRTFGLNIILGVFYSIGLMISPWIAIWLGNWR 226
            ..||     ::|||...     ..|:.|::.|..||..: ::....:|:|.|:...:|....|||
Human   193 ALRFAVATAVAGLSFSN-----VTLLTEWVGPSWRTQAV-VLAQCNFSLGQMVLAGLAYGFRNWR 251

  Fly   227 SYLWAASLPALGMLIFPLF--LHESVEWLLTKGKFDKAVNNLKSVAKFNGRQVEDSVFDEFIKHY 289
            ......:.|  |:|:|..|  |.||..||||:|:.|:|:..::..|..|.|::...:.::.:.
Human   252 LLQITGTAP--GLLLFFYFWALPESARWLLTRGRMDEAIQLIQKAASVNRRKLSPELMNQLVP-- 312

  Fly   290 REKLNSAQKKSSDTFMGMLRTPRLRKFTIILLIKSMIITIAFDILSRNVEGVGISPFKLFSYSGF 354
             ||..     .|...:.:.|.|:|||.|:|:.....:.::.:..||..|...|:..:......|.
Human   313 -EKTG-----PSGNALDLFRHPQLRKVTLIIFCVWFVDSLGYYGLSLQVGDFGLDVYLTQLIFGA 371

  Fly   355 VVLPGGLSIILFQNKIGRKGMACASLLVGAFITATTGYLVGTLDPANYSVLLGFMVCLARFGAVV 419
            |.:|...|.|....:.|||.....:|::|..:.....::     ||:..|::..:..:.:.....
Human   372 VEVPARCSSIFMMQRFGRKWSQLGTLVLGGLMCIIIIFI-----PADLPVVVTMLAVVGKMATAA 431

  Fly   420 AYDAEAQYAAEIIPTSVRGRGVANIHVVGNAFAFFSSYIIYLGTFYKPLPSLLISFLLIIGACLC 484
            |:.....|:||:.||.:|..|:..:.:........:..:|.||.::..||.|:...|.|:...||
Human   432 AFTISYVYSAELFPTILRQTGMGLVGIFSRIGGILTPLVILLGEYHAALPMLIYGSLPIVAGLLC 496

  Fly   485 LTLPETLHKQLPQTLEEGEI 504
            ..||||..:.|..||::.|:
Human   497 TLLPETHGQGLKDTLQDLEL 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17752	NP_650817.1	2A0119	11..498	CDD:273328	140/526 (27%)
SLC22A13	NP_004247.2	MFS_OAT	102..500	CDD:340932	112/423 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	511..551		2/6 (33%)