Protein Alignment CG17752 and SLC22A14

DIOPT Version :10

• Sequence 1: NP_650817.1
• Gene: CG17752 / 42337
• FlyBaseID: FBgn0038718
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: XP_006713479.2
• Gene: SLC22A14 / 9389
• HGNCID: 8495
• Length: 675
• Species: Homo sapiens
• Alignment Length: 538
• Identity: 131/538 - (24%)
• Similarity: 221/538 - (41%)
• Gaps: 65/538 - (12%)

  Fly     6 VLEKCGNFGPYQILLLGLYGYTNIVSSLHYFSQTLISFTPSHRCS-----------APVEEFSQN 59
            :|:..|.||.:|..|:.|....:|:|:...|:...:.......|:           :..|:.:..
Human   136 LLDAVGEFGTFQQRLVALTFIPSIMSAFFMFADHFVFTAQKPYCNTSWILAVGPHLSKAEQLNLT 200

  Fly    60 FTE-----LLSC-----------SVIQYDVDMTSFRDNKCSSWDFDKESNYESITTELEWVCDDA 108
            ..:     .|:|           |:||:.::.|   |.....|.: .::...|:..|.:.||...
Human   201 IPQAPNGSFLTCFMYLPVPWNLDSIIQFGLNDT---DTCQDGWIY-PDAKKRSLINEFDLVCGME 261

  Fly   109 YKLAVGQSFFFIGSALGSIFFGYLADRIGRLPACVLSTLTGASGDFFTSFVGSLPMFSFTRFISG 173
            .|....|..|..|..:||:.|..:.|::||.||.:||.|......|.|:|:.|..::.|.||  |
Human   262 TKKDTAQIMFMAGLPIGSLIFRLITDKMGRYPAILLSLLGLIIFGFGTAFMNSFHLYLFFRF--G 324

  Fly   174 LSMD-TQYVLMYI-LVFEYLSPQHRTFGLNIILG-VFYSIGLMISPWIAIWLGNWRSYLWAASLP 235
            :|.. ..|.:..| |..|:|..:||...  |||| .|:::|.::...||..|.:|:.......:.
Human   325 ISQSVVGYAISSISLATEWLVGEHRAHA--IILGHCFFAVGAVLLTGIAYSLPHWQLLFLVGGIL 387

  Fly   236 ALGMLIFPLFLHESVEWLLTKGKFDKAVNNLKSVAKFNGRQVEDSVFDEFIKHYREKLNSAQKKS 300
            .:..:.:...|.||..||:.|||..:|...|...|..|.:.:..::.|| ::..|:|:..|
Human   388 VIPFISYIWILPESPRWLMMKGKVKEAKQVLCYAASVNKKTIPSNLLDE-LQLPRKKVTRA---- 447

  Fly   301 SDTFMGMLRTPRLRKFTIILLIKSMIITIAFDILSRNVEGVGISPFKLFSYSGFVVLPGGLSIIL 365
              :.:...:..:|.|.|:::......::..:..||..:..:|:|..........:.:|..|..|.
Human   448 --SVLDFCKNRQLCKVTLVMSCVWFTVSYTYFTLSLRMRELGVSVHFRHVVPSIMEVPARLCCIF 510

  Fly   366 FQNKIGRKGMACASLLVGAFITATTGYLVGTLD---------PANYSVLLGFMVCLAR-FGAVVA 420
            ...:||||.....:||..........:|....|         ||.....:..:|.:.| |.....
Human   511 LLQQIGRKWSLAVTLLQAIIWCLLLLFLPEGEDGLRLKWPRCPATELKSMTILVLMLREFSLAAT 575

  Fly   421 YDAEAQYAAEIIPTSVRGRGVANIHVVGNAFAFFSSYIIYLGTFYKPLPSLLISF----LLIIGA 481
            ......|.||::||.:|..|:..:.:...|.|..|..||      ...||||..|    |.|:..
Human   576 VTVFFLYTAELLPTVLRATGLGLVSLASVAGAILSLTII------SQTPSLLPIFLCCVLAIVAF 634

  Fly   482 CLCLTLPETLHKQLPQTL 499
            .|...||||..:.|.::|
Human   635 SLSSLLPETRDQPLSESL 652

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17752	NP_650817.1	2A0119	11..498	CDD:273328	129/530 (24%)
SLC22A14	XP_006713479.2	MFS_OAT	229..641	CDD:340932	108/432 (25%)