Protein Alignment CG17752 and SLC22A6

DIOPT Version :10

• Sequence 1: NP_650817.1
• Gene: CG17752 / 42337
• FlyBaseID: FBgn0038718
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_004781.2
• Gene: SLC22A6 / 9356
• HGNCID: 10970
• Length: 563
• Species: Homo sapiens
• Alignment Length: 544
• Identity: 127/544 - (23%)
• Similarity: 228/544 - (41%)
• Gaps: 54/544 - (9%)

  Fly     1 MDLQRVLEKCGNFGPYQILLLGLYGYTNIVSSLHYFSQTLISFTPSHRCSAPVE-EFSQN----- 59
            |....:|::.|..|.:|.:.:.|.....::.:.|...|...:..|:|.|..|.: ..|:|
Human     1 MAFNDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCRPPADANLSKNGGLEV 65

  Fly    60 ---------------FTE------LLSCSVIQYDVDMTSFRDNKCSSWDFDKESNYESITTELEW 103
                           ||.      .|:.:    :.:.|...:.....|.:|..:...:|.||.:.
Human    66 WLPRDRQGQPESCLRFTSPQWGLPFLNGT----EANGTGATEPCTDGWIYDNSTFPSTIVTEWDL 126

  Fly   104 VCDDAYKLAVGQSFFFIGSALGSIFFGYLADRIGRLPACVLSTLTGASGDFFTSFVGSLPMFSFT 168
            ||.......:.||.:.:|..||::.|||||||:||....:|:.|..|......:|..:.|::...
Human   127 VCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAFAPNFPIYCAF 191

  Fly   169 RFISGLSMDTQYVLMYILVFEYLSPQHRTFGLNIILGVFYSIGLMISPWIAIWLGNWRSYLWAAS 233
            |.:||:::....:....|..|:: |.|....:..::|..||:|..:...:|..:.:||......|
Human   192 RLLSGMALAGISLNCMTLNVEWM-PIHTRACVGTLIGYVYSLGQFLLAGVAYAVPHWRHLQLLVS 255

  Fly   234 LPALGMLIFPLFLHESVEWLLTKGKFDKAVNNLKSVAKFNGRQVEDSVFDEFIKHYREKLN-SAQ 297
            .|.....|:..|..||..|..:.|:.|..:..|:.||:.||::      :|..|...|.|. |.|
Human   256 APFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKR------EEGAKLSMEVLRASLQ 314

  Fly   298 K-----KSSDTFMGMLRTPRLRKFTIILLIKSMIITIAFDILSRNVEGVGISPFKLFSYSGFVVL 357
            |     |...:.|.:||.|.||...:.|.:.....:.|:..|..:::|.|:|.:.:....|.|.|
Human   315 KELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDLQGFGVSIYLIQVIFGAVDL 379

  Fly   358 PGGLSIILFQNKIGRKGMACASLLVGAFITATTGYLVGTLDPANYSVLLGFMVCLARFGAVVAYD 422
            |..|...|..|.:||:....|:||:........|.:     |.:.|::...:..|.:.....:::
Human   380 PAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVI-----PQDQSIVRTSLAVLGKGCLAASFN 439

  Fly   423 AEAQYAAEIIPTSVRGRGVANIHVVGNAFAFFSSYIIYLGTFYKPLPSLLISFLLIIGACLCLTL 487
            ....|..|:.||.:|..|:.....:....:..|..:......|..:|..:...:.:..:.:.:.|
Human   440 CIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSMTAELYPSMPLFIYGAVPVAASAVTVLL 504

  Fly   488 PETLHKQLPQTLEEGEIFAKGEKW 511
            ||||.:.||.|:::.|     .:|
Human   505 PETLGQPLPDTVQDLE-----SRW 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17752	NP_650817.1	2A0119	11..498	CDD:273328	122/519 (24%)
SLC22A6	NP_004781.2	2A0119	11..515	CDD:273328	122/519 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	525..563