Protein Alignment CG17752 and slc22a3

DIOPT Version :10

• Sequence 1: NP_650817.1
• Gene: CG17752 / 42337
• FlyBaseID: FBgn0038718
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_001107932.1
• Gene: slc22a3 / 797890
• ZFINID: ZDB-GENE-080204-92
• Length: 554
• Species: Danio rerio
• Alignment Length: 573
• Identity: 147/573 - (25%)
• Similarity: 259/573 - (45%)
• Gaps: 74/573 - (12%)

  Fly     2 DLQRVLEKCGNFGPYQILLLGLYGYTNIVSSLHYFSQTLISFTPSHRC-SAPVEE---FSQN--- 59
            :...:|:..|:||.||..:..|.....::.:........:.:||.|.| :|.::|   ||:.
Zfish     3 NFDELLQHAGDFGFYQKRISVLGSLPILLLAFVLIGVVFLGYTPDHWCKTASLQEKCGFSEEQVR 67

  Fly    60 ------------FTE------------LLSCSVIQYDVDMTSFRDNKCS-SWDFDKESNYESITT 99
                        |::            .|||::..::   .|...:.|: .|.|::  |..:|.|
Zfish    68 DLTVPRTGARGAFSKCVKFDDALRNGSALSCNISIFN---NSTHLSACNEGWTFNE--NRTTIVT 127

  Fly   100 ELEWVCDDAYKLAVGQSFFFIGSALGSIFFGYLADRIGRLPACVLSTL--TGASGDFFTSFVGS- 161
            |...||:|::...:.|.....|..:|::..||||||.|| .:|.::::  .|.||   |..:.|
Zfish   128 EFSLVCEDSWLADLNQVSLAGGFFIGALVTGYLADRFGR-KSCFIASIFGLGVSG---TCIIFSP 188

  Fly   162 -LPMFSFTRFISGLSMDTQYVLMYILVFEYLSPQHRTFGLNIILGVFYSIGLMISPWIAIWLGNW 225
             .|:..|.|.:.|......:...|:|:.|:....:|.| ::::...|||:||::.|.:|.::.:|
Zfish   189 YYPLLLFFRCLQGFFAKGAWTATYVLIIEFFGSNNRKF-VSVMSRTFYSLGLVLLPALAYYIPSW 252

  Fly   226 RSYLWAASLPALGMLIFPLFLHESVEWLLTKGKFDKAVNNLKSVAKFNGRQVEDSV--FDEFIKH 288
            |:...|.:||....||:...:.||..|||::.|..:|::.:||:||.|.|.:.:..  .|..|:.
Zfish   253 RNLQLAMTLPTFIFLIYHWVIPESPRWLLSQRKTKEALSIVKSIAKCNKRSLPEDFHEMDLLIEK 317

  Fly   289 YREKLNSAQKKSSDTFMGMLRTPRLRKFTIILLIKSMIITIAFDILSRNVEGVGISPFKLFSYSG 353
            ..|.:..:.|   |.|    :||::||.|.||:.......:.|..|...:...|.:.|..|..|.
Zfish   318 QEEIMRPSYK---DLF----KTPKMRKHTFILIYAWFTGAVVFQGLVLRLGITGDNVFLDFLISA 375

  Fly   354 FVVLPGGLSIILFQNKIGRKG-MACASLLVGAFITATTGYLVGTLDPANYSVLLGFMVCLARFGA 417
            .|.||.||......::|||:. ||..:.:.||...|     |..:.| |.|.|...:..:.|...
Zfish   376 VVELPTGLIFYFLVDRIGRRPLMATVNFIGGAACLA-----VPFISP-NISWLRRTIAIVGRLAV 434

  Fly   418 VVAYDAEAQYAAEIIPTSVRGRGVANIHVVGNAFAFFSSYIIY-LGTFYKPLPSLLISFLLIIGA 481
            .:..:.......|:.||.:|..||:......:..|..:.:|:| |.:.::.||.|:...:.::.:
Zfish   435 AIGNETVNFANTELYPTPLRNLGVSVCSSASDIGAVVAPFILYRLASIWQELPLLVYGVMSVLYS 499

  Fly   482 CLCLTLPETLHKQLPQTLEEGEIFAKGEKWYFFPCFSRKRQSNKSESQLESAN 534
            .|.:.|||.....||:|:::.|...           ||.::..|..:|....|
Zfish   500 GLVMLLPEMKGVDLPETVDDVENLR-----------SRHKRKEKDGAQFPEIN 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17752	NP_650817.1	2A0119	11..498	CDD:273328	139/526 (26%)
slc22a3	NP_001107932.1	MFS_SLC22A1_2_3	105..506	CDD:340937	116/420 (28%)