Protein Alignment CG17752 and Slc22a4

DIOPT Version :10

• Sequence 1: NP_650817.1
• Gene: CG17752 / 42337
• FlyBaseID: FBgn0038718
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_071606.1
• Gene: Slc22a4 / 64037
• RGDID: 621149
• Length: 553
• Species: Rattus norvegicus
• Alignment Length: 534
• Identity: 137/534 - (25%)
• Similarity: 239/534 - (44%)
• Gaps: 47/534 - (8%)

  Fly     2 DLQRVLEKCGNFGPYQILLLGLYGYTNIVSSLHYFSQTLISFTPSHRC---------------SA 51
            |...|:...|::||:|.|:..|...:.|.:..:..|...::.||.|||               |.
  Rat     3 DYDEVIAFLGDWGPFQRLIFFLLSASIIPNGFNGMSVVFLAGTPEHRCLVPHTVNLSSAWRNHSI 67

  Fly    52 PVE-----EFSQNFTELLSCSVIQY---------DVDMTSFRDNKC-SSWDFDKESNYESITTEL 101
            |:|     :..|:.......::..:         |||:.......| ..|::.|:....:|.||.
  Rat    68 PLETKDGRQVPQSCRRYRLATIANFSALGLEPGLDVDLEQLEQESCLDGWEYSKDVFLSTIVTEW 132

  Fly   102 EWVCDDAYKLAVGQSFFFIGSALGSIFFGYLADRIGRLPA--CVLSTLTGASGDFFTSFVGSLPM 164
            ..||:|.:|..:..|.||:|...||...|.|:||.||...  ..::..||.|  |...|..:..|
  Rat   133 NLVCEDDWKTPLTTSLFFVGVLCGSFVSGQLSDRFGRKKVLFATMAVQTGFS--FVQIFSTNWEM 195

  Fly   165 FSFTRFISGLSMDTQYVLMYILVFEYLSPQHRTFGLNIILGVFYSIGLMISPWIAIWLGNWRSYL 229
            |:....|.|:...:.||:.:||..|.||...|.....:.:..|::||.|:.|..|.::.:||..|
  Rat   196 FTVLFAIVGMGQISNYVVAFILGTEILSKSVRILFSTLGVCTFFAIGYMVLPLFAYFIRDWRMLL 260

  Fly   230 WAASLPALGMLIFPL--FLHESVEWLLTKGKFDKAVNNLKSVAKFNGRQVEDSVFDEFIKHYREK 292
            .|.:||  |:...||  |:.||..||:::.:|::|...::..||.||......:||..   ..::
  Rat   261 LALTLP--GLFCVPLWWFIPESPRWLISQRRFEEAEQIIQKAAKMNGIMAPAVIFDPL---ELQE 320

  Fly   293 LNSAQKKSSDTFMGMLRTPRLRKFTIILLIKSMIITIAFDILSRNVEGVGISPFKLFSYSGFVVL 357
            |||. |:.....:.:.:|..:...|::.::..|:.::.:..||.||..:....:.....||.:.:
  Rat   321 LNSL-KQQKVFILDLFKTRNIATITVMSVMLWMLTSVGYFALSLNVPNLHGDVYLNCFLSGLIEV 384

  Fly   358 PGGLSIILFQNKIGRKGMACASLLVGAFITATTGYLVGTLDPANYSVLLGFMVCLARFGAVVAYD 422
            |...:..|....:.|:.:....|..|..:     .|:..:.|.:|:.:...:|.|.:||...|:.
  Rat   385 PAYFTAWLLLRTLPRRYIIAGVLFWGGGV-----LLLVQVVPEDYNFVSIGLVMLGKFGVTSAFS 444

  Fly   423 AEAQYAAEIIPTSVRGRGVANIHVVGNAFAFFSSYIIYLGTFYKPLPSLLISFLLIIGACLCLTL 487
            ....:.||:.||.||...|....:.....:..:.|.:|||.:.:.||.:|:..|.::...:.|..
  Rat   445 MLYVFTAELYPTLVRNMAVGITSMASRVGSIIAPYFVYLGAYNRLLPYILMGSLTVLIGIITLFF 509

  Fly   488 PETLHKQLPQTLEE 501
            ||:....||:.||:
  Rat   510 PESFGVTLPENLEQ 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17752	NP_650817.1	2A0119	11..498	CDD:273328	133/520 (26%)
Slc22a4	NP_071606.1	2A0119	12..519	CDD:273328	132/519 (25%)