Protein Alignment CG17752 and Slc22a17

DIOPT Version :10

• Sequence 1: NP_650817.1
• Gene: CG17752 / 42337
• FlyBaseID: FBgn0038718
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_001347335.2
• Gene: Slc22a17 / 59049
• MGIID: 1926225
• Length: 627
• Species: Mus musculus
• Alignment Length: 604
• Identity: 148/604 - (24%)
• Similarity: 247/604 - (40%)
• Gaps: 139/604 - (23%)

  Fly     1 MDLQRVLEKCGNFGPYQILLLGLYGYTNIVSSLHYFSQTLISFTPSHRC-------SAPVEEFSQ 58
            :..:.:|.:.|..|..|.|.|||.....:..:|...|..:.:..|...|       :|...|...
Mouse    74 LSFEALLAQVGALGGGQQLQLGLCCLPVLFVALGMASDPIFTLAPPLHCHYGALPPNASGWEQPP 138

  Fly    59 NFTEL------LSCSVIQYDVDMTSFRDNKCSSW---DFD---KESNYES---ITTEL--EW--V 104
            |.:.:      |:.|.....|..|   |..||.:   ||:   |:.:|..   :||..  :|  |
Mouse   139 NSSGVSVAGAALAASAASGVVTST---DPSCSGFAPPDFNHCLKDWDYNGLPVLTTNAIGQWDLV 200

  Fly   105 CDDAYKLAVGQSFFFIGSALGSIFFGYLADRIGRLPACVLSTL-----TGASGDFFTSFVGSLPM 164
            ||..:::.:.|..|.:|.|.|.:|.||.|||.|| ...||.||     .|..|....|..|.:.:
Mouse   201 CDLGWQVILEQILFILGFASGYLFLGYPADRFGR-RGIVLLTLGLVGPCGVGGAAAGSSTGIMAL 264

  Fly   165 FSFTRFISGLSMDTQYVLMYILVFEYLSPQHRTFGLNIIL--------GVFYSIGLMISPWIAIW 221
                ||:.|..:....:.:|::..|...|..|   |.:.|        |.|..:||      |:.
Mouse   265 ----RFLLGFLLAGVDLGVYLMRLELCDPTQR---LRVALAGELVGVGGHFLFLGL------ALV 316

  Fly   222 LGNWRSYLWAASLPALGMLIF---PLFLHESVEWLLTKGKFDKAVNNLKSVAKFN-------GRQ 276
            ..:||......:.|.:..|.:   .||| ||..||:.|.:.::|.:.|:.:|:.|       |.:
Mouse   317 SKDWRFLQRMITAPCILFLFYGWPGLFL-ESARWLIVKRQIEEAQSVLRILAERNRPHGQMLGEE 380

  Fly   277 VEDSVFDEFIKHYREKLNSAQKKSSDTFMGMLRTPRLRKFTIIL----LIKSMIITIAFDILSRN 337
            .::::        :|..|:....::.||          .|..:|    :.|:::|....:.::..
Mouse   381 AQEAL--------QELENTCPLPATSTF----------SFASLLNYRNIWKNLLILGFTNFIAHA 427

  Fly   338 VE------GVGISPFKLFSYSGFVVLPGGLSII------LFQNKIGRKGMACASLLVGAFITATT 390
            :.      |.|.||...:..|   :|..|.:.:      :..::.||:|:    ||:...:|...
Mouse   428 IRHCYQPVGGGGSPSDFYLCS---LLASGTAALACVFLGVTVDRFGRRGI----LLLSMTLTGIA 485

  Fly   391 G-YLVGTLDPANYSVLLGFMVCLARFGAVVAYDAEAQYAAEIIPTSVRGRGVANIHVVGNAFAFF 454
            . .|:|..|..|.:.:..|.| |..|.:..:.......|:|:|||:|||||:..|..:|
Mouse   486 SLVLLGLWDYLNDAAITTFSV-LGLFSSQASAILSTLLASEVIPTTVRGRGLGLIMALG------ 543

  Fly   455 SSYIIYLGTFYKPLPSLLI---SFL--LIIGAC--LC----LTLPETLHKQLPQTLEEGEIFAKG 508
                 .||....|...|.:   :||  :::.||  ||    :.||||..|.||:.|.:||:..:
Mouse   544 -----ALGGLSCPAQRLHMGHGAFLQHVVLAACALLCILSIMLLPETKRKLLPEVLRDGELCRR- 602

  Fly   509 EKWYFFPCFSRKRQSNKSE 527
                  |...|:...|:.:
Mouse   603 ------PSLLRQPPPNRCD 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17752	NP_650817.1	2A0119	11..498	CDD:273328	141/563 (25%)
Slc22a17	NP_001347335.2	MFS_SLC22A17	170..583	CDD:341003	113/464 (24%)