Protein Alignment CG17752 and SLC22A11

DIOPT Version :10

• Sequence 1: NP_650817.1
• Gene: CG17752 / 42337
• FlyBaseID: FBgn0038718
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_060954.1
• Gene: SLC22A11 / 55867
• HGNCID: 18120
• Length: 550
• Species: Homo sapiens
• Alignment Length: 571
• Identity: 141/571 - (24%)
• Similarity: 242/571 - (42%)
• Gaps: 72/571 - (12%)

  Fly     1 MDLQRVLEKCGNFGPYQILLLGLYGYTNIVSSLHYFSQTLI-SFT---PSHRCSAPV----EEFS 57
            |...::||:.|..|.:|.|.:    .|.|:..|...||.|: :|:   |.|||...:    ...|
Human     1 MAFSKLLEQAGGVGLFQTLQV----LTFILPCLMIPSQMLLENFSAAIPGHRCWTHMLDNGSAVS 61

  Fly    58 QNFT--ELLSCSV---------------------IQYDVDMTSFRD---NKC-SSWDFDKESNYE 95
            .|.|  .||:.|:                     :..:...||:.:   ..| ..|.:|:.....
Human    62 TNMTPKALLTISIPPGPNQGPHQCRRFRQPQWQLLDPNATATSWSEADTEPCVDGWVYDRSVFTS 126

  Fly    96 SITTELEWVCDDAYKLAVGQSFFFIGSALGSIFFGYLADRIGRLP----ACVLSTLTGASGDFFT 156
            :|..:.:.||.......:.||.|..|..:||..:|.|:.|.||.|    .|:...:.|.|..|..
Human   127 TIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPMLSWCCLQLAVAGTSTIFAP 191

  Fly   157 SFVGSLPMFSFTRFISGLSMDTQYVLMYILVFEYLSPQHRTFGLNIILGVFYSIGLMISPWIAIW 221
            :||    ::...||::...|...::....|:.|:.:...|...:.:: |..:|.|......:|..
Human   192 TFV----IYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVV-GCAFSAGQAALGGLAFA 251

  Fly   222 LGNWRSYLWAASLPALGMLIFPLFLHESVEWLLTKGKFDKAVNNLKSVAKFNG-RQVEDSVFDEF 285
            |.:||:...|||:|...:.:...:|.||..||:.|||.|:|:..|:.||:.|| ::.::...:..
Human   252 LRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQELRKVARINGHKEAKNLTIEVL 316

  Fly   286 IKHYREKLNSAQKKSSDTFMGMLRTPRLRKFTIILLIKSMIITIAFDILSRNVEGVGISPFKLFS 350
            :...:|::.||::..|  .:.:...|.||..:..:|:.:..:.|::..|..:::.:|...|.|.:
Human   317 MSSVKEEVASAKEPRS--VLDLFCVPVLRWRSCAMLVVNFSLLISYYGLVFDLQSLGRDIFLLQA 379

  Fly   351 YSGFVVLPGGLSIILFQNKIGRKGMACASLLVGAFITATTGYLVGTLDPANYSVLLGFMVCLAR- 414
            ..|.|...|..:..|..:.:||:     ::..|:...|....|...|.|.:...|......|.:
Human   380 LFGAVDFLGRATTALLLSFLGRR-----TIQAGSQAMAGLAILANMLVPQDLQTLRVVFAVLGKG 439

  Fly   415 -FGAVVAYDAEAQYAAEIIPTSVRGRGVANIHVVGNAFAFFSSYIIYLGTFYKPLPSLLISFLLI 478
             ||  ::......|.||:.||.||......:|.||...|.....|:........||.||...:.|
Human   440 CFG--ISLTCLTIYKAELFPTPVRMTADGILHTVGRLGAMMGPLILMSRQALPLLPPLLYGVISI 502

  Fly   479 IGACLCL-TLPETLHKQLPQTLEEGEIFAKGEKWYFFPCFSRKRQSNKSES 528
            ..:.:.| .||||....||.|:::.|    .:|       |...|.|:.|:
Human   503 ASSLVVLFFLPETQGLPLPDTIQDLE----SQK-------STAAQGNRQEA 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17752	NP_650817.1	2A0119	11..498	CDD:273328	131/529 (25%)
SLC22A11	NP_060954.1	MFS_OAT	106..511	CDD:340932	102/418 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	531..550		5/19 (26%)