Protein Alignment CG17752 and Slc22a22

DIOPT Version :10

• Sequence 1: NP_650817.1
• Gene: CG17752 / 42337
• FlyBaseID: FBgn0038718
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: XP_036015188.1
• Gene: Slc22a22 / 210463
• MGIID: 2446114
• Length: 587
• Species: Mus musculus
• Alignment Length: 618
• Identity: 148/618 - (23%)
• Similarity: 248/618 - (40%)
• Gaps: 128/618 - (20%)

  Fly     1 MDLQRVLEKCGNFGPYQILLLGLYGYTNIVSSLHYFSQTLISFTPSHRCSAPVE----EFS--QN 59
            ||...:|...|:.|.:||.::.|....::|.|.|...:...:..|:|.||..::    |.|  .|
Mouse     1 MDFDEILHHVGDSGRFQICMIILLNILSLVLSPHDVLENFTAAIPAHHCSINLDNSRSEVSTDMN 65

  Fly    60 FT--ELLSCSV-------------IQY------DVDMTSFRDNKCSS------WDFDKESNYESI 97
            .|  :|:..|:             .:|      |.::::|...:..:      |.:|......:|
Mouse    66 LTTEDLMKVSIPMGPNQKPEQCRRFRYTQWQFLDSNISTFNSTELETEPCLDGWTYDHSVFTSTI 130

  Fly    98 TTE-----LEW-------------VCDDAYKLAVG--------QSFFF-------IGSALGSIFF 129
            .||     ..|             .|::..|.:|.        |||.:       .|..:.....
Mouse   131 VTEGLSPPQPWDSDQYYHTKHEISPCEEGLKSSVKVWDLVCDFQSFKYYAQATSLAGHLVSCPLS 195

  Fly   130 GYLADRIGRLPACVLSTLT-GASGDFFTSFVGSLPMFSFTRFISGLSMDTQYVLMYILVFEYLSP 193
            |.::||.||.|..:..:|. ||.|. :.:|..:..::...||:......|..:...|||.|..|.
Mouse   196 GIISDRFGRKPLLMYCSLAYGAVGT-YCAFAPNFSVYCVLRFLLSAFQSTILINSLILVLEEASV 259

  Fly   194 Q-HRTFGLNIILGVFYSIGLMISPWIAIWLGNWRSYLWAASLPALGMLIFPLFLHESVEWLLTKG 257
            | |.|  :.::.|:|.|||..:...:|..:.:|.....|.:||.....:...::.|||.||:..|
Mouse   260 QWHPT--IIVLSGLFNSIGQGVLGGLAYVISDWHLLQLAYALPFFIFFVLFCWVPESVRWLIITG 322

  Fly   258 KFDKAVNNLKSVAKFNGRQ--VEDSVFDEFIKHYREKLNSAQK--KSSDTFMGMLRTPRLRKFTI 318
            |.|:|...|:.:|..||::  .::...::.....::.:||..|  :..|.|:    .|.:||  |
Mouse   323 KTDQAWKELQRIASINGKKGIAQNLTTEDLRSKLKKDVNSTGKLFRIKDIFI----NPLIRK--I 381

  Fly   319 ILLIKSMIITIAFDI--LSRNVEGVGISPFKLFSYSGFVVLPG-GLSIILFQNKIGRKGMACASL 380
            :|...|::....|..  |..:|:.:|.:.|....:.|.:.:|. .|:....:|...|..:|...|
Mouse   382 VLSNSSLLFAELFSFVGLLLDVQLLGKNMFLTQIFLGAIDVPSKSLTYFTIRNVSRRPLIAFLLL 446

  Fly   381 LVGAFITAT-----TGYLVGTLDPANYSVLLGFMVCLARFGAVVAYDAEAQYAAEIIPTSVR--- 437
            ..|:.||.|     ..|::.|:     ..:|| ..|.|.|..:     ...|..|:.|..:|
Mouse   447 TTGSCITITIFISEEMYVLRTI-----IFILG-KGCFAAFTCI-----STTYINELSPVELRSTL 500

  Fly   438 -GRGVANIHVVGNAFAF---FSSYIIYLGTFYKPLPSLLISFLLIIGACLCLTLPETLHKQLPQT 498
             |..:|.:.:.|...|.   ...|.:|       ||.:|...|.|:.....|.||||.:  ||.|
Mouse   501 NGVFLAVVRLAGVLSALTLATRKYFVY-------LPMILYGVLPIVATISILFLPETFN--LPHT 556

  Fly   499 LEEGEIFAKGEKWYFFPCFSRKRQSNKSESQLE 531
                :|....||        |||..:|:.|:.|
Mouse   557 ----DIIKDMEK--------RKRLMSKNISKKE 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17752	NP_650817.1	2A0119	11..498	CDD:273328	135/573 (24%)
Slc22a22	XP_036015188.1	MFS_OAT	108..548	CDD:340932	108/466 (23%)