Protein Alignment CG17752 and Slc22a12

DIOPT Version :10

• Sequence 1: NP_650817.1
• Gene: CG17752 / 42337
• FlyBaseID: FBgn0038718
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_033229.3
• Gene: Slc22a12 / 20521
• MGIID: 1195269
• Length: 553
• Species: Mus musculus
• Alignment Length: 555
• Identity: 136/555 - (24%)
• Similarity: 235/555 - (42%)
• Gaps: 80/555 - (14%)

  Fly     1 MDLQRVLEKCGNFGPYQ----ILLLGLYGYTNIVSSLHYFSQTLISFTPSHRCSAPVEEFSQNFT 61
            |....:|::.|..|.:|    :.|:....:....:.|..||..:    |.|||..|:.:.|.:..
Mouse     1 MAFPELLDRVGGLGRFQLFQTVALVTPILWVTTQNMLENFSAAV----PHHRCWVPLLDNSTSQA 61

  Fly    62 E---------LLSCSV---------------------IQYDVDMTSFRD---NKC-SSWDFDKES 92
            .         ||:.|:                     .:.:...|::.|   ..| ..|.:|..:
Mouse    62 SIPGDLGPDVLLAVSIPPGPDQQPHQCLRFRQPQWQLTESNATATNWSDAATEPCEDGWVYDHST 126

  Fly    93 NYESITTELEWVCDDAYKLAVGQSFFFIGSALGSIFFGYLADRIGRLPACVLSTLTGASGDFFTS 157
            ...:|.|..:.||:......:.||.|..|..:|:...|:.:||.||......|.|..:......:
Mouse   127 FRSTIVTTWDLVCNSQALRPMAQSIFLAGILVGAAVCGHASDRFGRRRVLTWSYLLVSVSGTAAA 191

  Fly   158 FVGSLPMFSFTRF-----ISGLSMDTQYVLMYILVFEYLSPQHRTFGLNI-ILGVFYSIGLMISP 216
            |:.:.|::...||     ::|:.|:|..:||     |:.|.|.....:.: .||  :|.|.:::.
Mouse   192 FMPTFPLYCLFRFLLASAVAGVMMNTASLLM-----EWTSAQGSPLVMTLNALG--FSFGQVLTG 249

  Fly   217 WIAIWLGNWRSYLWAASLPALGMLIFPLFLHESVEWLLTKGKFDKAVNNLKSVAKFNGRQVE-DS 280
            .:|..:.:||....|.|.|.....::..:|.||..||:|.||.|:.:..|:.||..|.|:.| |:
Mouse   250 SVAYGVRSWRMLQLAVSAPFFLFFVYSWWLPESARWLITVGKLDQGLQELQRVAAVNRRKAEGDT 314

  Fly   281 VFDEFIKHYREKLNSAQKKSSDTFMG-MLRTPRLRKFTIILLIKSMIITIAFDI----LSRNVEG 340
            :..|.::...|:..|..|..:.  :| :|.||.||..|||    ||:...||..    |:.:::.
Mouse   315 LTMEVLRSAMEEEPSRDKAGAS--LGTLLHTPGLRHRTII----SMLCWFAFGFTFYGLALDLQA 373

  Fly   341 VGISPFKLFSYSGFVVLPGGLSIILFQNKIGRKGMACASLLVGAFITATTGYLV----GTLDPAN 401
            :|.:.|.|.:..|.|..|.....:|..:::||: :...|.||...:...:..||    |.|..|.
Mouse   374 LGSNIFLLQALIGIVDFPVKTGSLLLISRLGRR-LCQVSFLVLPGLCILSNILVPHGMGVLRSAL 437

  Fly   402 YSVLLGFMVCLARFGAVVAYDAEAQYAAEIIPTSVRGRGVANIHVVGNAFAFFSSYIIYLGTFYK 466
            ..:.||   ||..     |:.....:::|:.||.:|...|....|.....|.....:..||.:..
Mouse   438 AVLGLG---CLGG-----AFTCITIFSSELFPTVIRMTAVGLCQVAARGGAMLGPLVRLLGVYGS 494

  Fly   467 PLPSLLISFLLIIGACLCLTLPETLHKQLPQTLEE 501
            .:|.|:...:.::.....|.||||.:..||.|:::
Mouse   495 WMPLLVYGVVPVLSGLAALLLPETKNLPLPDTIQD 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17752	NP_650817.1	2A0119	11..498	CDD:273328	133/540 (25%)
Slc22a12	NP_033229.3	MFS_OAT	109..516	CDD:340932	110/428 (26%)