Protein Alignment CG17752 and Slc22a3

DIOPT Version :10

• Sequence 1: NP_650817.1
• Gene: CG17752 / 42337
• FlyBaseID: FBgn0038718
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_035525.1
• Gene: Slc22a3 / 20519
• MGIID: 1333817
• Length: 551
• Species: Mus musculus
• Alignment Length: 573
• Identity: 146/573 - (25%)
• Similarity: 264/573 - (46%)
• Gaps: 74/573 - (12%)

  Fly     5 RVLEKCGNFGPYQ---ILLLGLYGYT------NIV----SSLHYFSQTLISFTPSHRCS-APVEE 55
            :.|.|.|.||.:|   .|||.|.|.|      .:|    ...:|:.:...:...:.||: :|.||
Mouse     6 QALRKAGEFGRFQRRVFLLLCLTGVTFAFLFVGVVFLGSQPDYYWCRGPRATALAERCAWSPEEE 70

  Fly    56 FSQNFTEL-------------------------LSCSVIQYDVDMTSFRDN-----KCSSWDFDK 90
            ::....||                         |||.      .:|:|.:.     .||. |:..
Mouse    71 WNLTTPELHVPAERRGQGHCHRYLLEATNTSSELSCD------PLTAFPNRSAPLVSCSG-DWRY 128

  Fly    91 ESNYESITTELEWVCDDAYKLAVGQSFFFIGSALGSIFFGYLADRIGRLPACVLSTL-TGASGDF 154
            ...:.:|.::.:.||.:|:.|.:.|:...:|...|:...||.|||.|||...::|.. .|.:| .
Mouse   129 VETHSTIVSQFDLVCSNAWMLDLTQAILNLGFLAGAFTLGYAADRYGRLIIYLISCFGVGITG-V 192

  Fly   155 FTSFVGSLPMFSFTRFISGLSMDTQYVLMYILVFEYL-SPQHRTFGLNIILGVFYSIGLMISPWI 218
            ..:|..:..:|...||:.|:.....::..:::|.|.: |.|.|..|  |::.:|:::|::|.|.|
Mouse   193 VVAFAPNFSVFVIFRFLQGVFGKGAWMTCFVIVTEIVGSKQRRIVG--IVIQMFFTLGIIILPGI 255

  Fly   219 AIWLGNWRSYLWAASLPALGMLIFPLFLHESVEWLLTKGKFDKAVNNLKSVAKFNGRQVEDSVFD 283
            |.:..:|:....|.|||:...|::...:.||..||:|:.:.:||:..|:.|||.||:.:.
Mouse   256 AYFTPSWQGIQLAISLPSFLFLLYYWVVPESPRWLITRKQGEKALQILRRVAKCNGKHLS----- 315

  Fly   284 EFIKHYREKLNSAQKKSSDTFMGMLRTPRLRKFTIILLIKSMIITIAFDILSRNVEGVGISPFKL 348
               .:|.|...:.::.|:.:.:.::|||::||.|:||:.......:.:..|...:..:|.:.:..
Mouse   316 ---SNYSEITVTDEEVSNPSCLDLVRTPQMRKCTLILMFAWFTSAVVYQGLVMRLGLIGGNLYID 377

  Fly   349 FSYSGFVVLPGGLSIILFQNKIGRKGMACASLLVGAFITATTGYLVGTLDPANYSVLLGFMVCLA 413
            |..||.|.|||.|.|:|...::||:....||.:|.......|.:|     |.....|...:..|.
Mouse   378 FFISGLVELPGALLILLTIERLGRRLPFAASNIVAGVSCLVTAFL-----PEGIPWLRTTVATLG 437

  Fly   414 RFGAVVAYDAEAQYAAEIIPTSVRGRGVANIHVVGNAFAFFSSYIIY-LGTFYKPLPSLLISFLL 477
            |.|..:|::......:|:.||::|..||:....:.:.....:.:::: |...:..||.::...|.
Mouse   438 RLGITMAFEIVYLVNSELYPTTLRNFGVSLCSGLCDFGGIIAPFLLFRLAAIWLELPLIIFGILA 502

  Fly   478 IIGACLCLTLPETLHKQLPQTLEEGEIFAKGEKWYFFPCFSRKRQSNKSESQL 530
            .:...|.:.||||....||:|:|:.|.....:   ...| .||:::..|.|.:
Mouse   503 SVCGGLVMLLPETKGIALPETVEDVEKLGSSQ---LHQC-GRKKKTQVSTSDV 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17752	NP_650817.1	2A0119	11..498	CDD:273328	136/533 (26%)
Slc22a3	NP_035525.1	2A0119	12..523	CDD:273328	136/533 (26%)
		Proline-rich sequence. /evidence=ECO:0000250|UniProtKB:O75751	284..288		2/3 (67%)