Protein Alignment CG17752 and SLC22A12

DIOPT Version :10

• Sequence 1: NP_650817.1
• Gene: CG17752 / 42337
• FlyBaseID: FBgn0038718
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: XP_006718493.1
• Gene: SLC22A12 / 116085
• HGNCID: 17989
• Length: 578
• Species: Homo sapiens
• Alignment Length: 569
• Identity: 133/569 - (23%)
• Similarity: 229/569 - (40%)
• Gaps: 83/569 - (14%)

  Fly     1 MDLQRVLEKCGNFGPYQIL-LLGLYGYTNIVSSLHYFSQTLI----SFTPSHRCSAPVEEFSQNF 60
            |....:|:..|..|.:|:| .:.|     :||.:...:|:::    :..|||||.||:.:.|...
Human     1 MAFSELLDLVGGLGRFQVLQTMAL-----MVSIMWLCTQSMLENFSAAVPSHRCWAPLLDNSTAQ 60

  Fly    61 TELL----------------------SC--------SVIQYDVDMTSFRD---NKC-SSWDFDKE 91
            ..:|                      .|        .::..:...||:.:   ..| ..|.:|:.
Human    61 ASILGSLSPEALLAISIPPGPNQRPHQCRRFRQPQWQLLDPNATATSWSEADTEPCVDGWVYDRS 125

  Fly    92 SNYESITTELEWVCDDAYKLAVGQSFFFIGSALGSIFFGYLADRIGRLPACVLSTLTGASGDFFT 156
            ....:|..:...|||......:.||.:..|..:|:...|..:||.||......|.|..|......
Human   126 IFTSTIVAKWNLVCDSHALKPMAQSIYLAGILVGAAACGPASDRFGRRLVLTWSYLQMAVMGTAA 190

  Fly   157 SFVGSLPMFSFTRF-----ISGLSMDTQYV--------------------LMYILVFEYLSPQHR 196
            :|..:.|::...||     ::|:.|:|..:                    |..:.|.|:.:.:.|
Human   191 AFAPAFPVYCLFRFLLAFAVAGVMMNTGTLRRSLTWRHAGGLHAGSRAEPLGLLAVMEWTAARAR 255

  Fly   197 TFGLNI-ILGVFYSIGLMISPWIAIWLGNWRSYLWAASLPALGMLIFPLFLHESVEWLLTKGKFD 260
            ...:.: .||  :|.|..::..:|..:.:|.......|:|.....::..:|.||..||||.|:.|
Human   256 PLVMTLNSLG--FSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAESARWLLTTGRLD 318

  Fly   261 KAVNNLKSVAKFNGR-QVEDSVFDE-FIKHYREKLNSAQKKSSDTFMG-MLRTPRLRKFTIILLI 322
            ..:..|..||..||: .|:|::..| .:...||:|:..|..:|   :| :||.|.||..|.|..:
Human   319 WGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPAS---LGTLLRMPGLRFRTCISTL 380

  Fly   323 KSMIITIAFDILSRNVEGVGISPFKLFSYSGFVVLPGGLSIILFQNKIGRKGMACASLLVGAFIT 387
            ........|..|:.:::.:|.:.|.|..:.|.|.:|..:..:|..:.:||:....||||:....
Human   381 CWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLSHLGRRPTLAASLLLAGLC- 444

  Fly   388 ATTGYLVGTLDPANYSVLLGFMVCLARFGAVVAYDAEAQYAAEIIPTSVRGRGVANIHVVGNAFA 452
                .|..||.|.....|...:..|...|...|:.....|::|:.||.:|...|....:.....|
Human   445 ----ILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFPTVLRMTAVGLGQMAARGGA 505

  Fly   453 FFSSYIIYLGTFYKPLPSLLISFLLIIGACLCLTLPETLHKQLPQTLEE 501
            .....:..||.....||.|:...:.::.....|.||||....||.|:::
Human   506 ILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLLPETQSLPLPDTIQD 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17752	NP_650817.1	2A0119	11..498	CDD:273328	130/554 (23%)
SLC22A12	XP_006718493.1	MFS_OAT	109..541	CDD:340932	104/441 (24%)