Protein Alignment CG17751 and SLC22A6

DIOPT Version :9

• Sequence 1: NP_650816.3
• Gene: CG17751 / 42336
• FlyBaseID: FBgn0038717
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_004781.2
• Gene: SLC22A6 / 9356
• HGNCID: 10970
• Length: 563
• Species: Homo sapiens
• Alignment Length: 556
• Identity: 130/556 - (23%)
• Similarity: 227/556 - (40%)
• Gaps: 62/556 - (11%)

  Fly     1 MDLQSVLEKCGNFGPYQILLLGLFGYTNIVSSLHYFSQTIISFTPSHRCS--------------- 50
            |....:|::.|..|.:|.:.:.|.....::.:.|...|...:..|:|.|.
Human     1 MAFNDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCRPPADANLSKNGGLEV 65

  Fly    51 -RPEDYQPNSTSLLSCSVMQFDKEF-------------KCT-SWDFERESNYESITTELEWVCDD 100
             .|.|.|....|.|..:..|:...|             .|| .|.::..:...:|.||.:.||..
Human    66 WLPRDRQGQPESCLRFTSPQWGLPFLNGTEANGTGATEPCTDGWIYDNSTFPSTIVTEWDLVCSH 130

  Fly   101 AYKLAVGQSFFFIGSALGSIFFGYLADRIGRLPACVLSTLTGASGDFFTSFVGSLPWFSFTRFIS 165
            .....:.||.:.:|..||::.|||||||:||....:|:.|..|......:|..:.|.:...|.:|
Human   131 RALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAFAPNFPIYCAFRLLS 195

  Fly   166 GLFMDTQYVLMYILVFEYLSPQHRTFGLNIILGVFYCVGLMISPWIAIWVTNWRNYLWAASLPAL 230
            |:.:....:....|..|:: |.|....:..::|..|.:|..:...:|..|.:||:.....|.|..
Human   196 GMALAGISLNCMTLNVEWM-PIHTRACVGTLIGYVYSLGQFLLAGVAYAVPHWRHLQLLVSAPFF 259

  Fly   231 GMLLFPVFLHESAEWLLTKGKFEKAEKSLRGVAKFNGRQVDDSVFDEFIKHYREKLNNS------ 289
            ...::..|..|||.|..:.|:.:...::|:.||:.||::      :|..|...|.|..|
Human   260 AFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKR------EEGAKLSMEVLRASLQKELT 318

  Fly   290 QNKSSDTFMGMLRTPRLRKFTIILLIKSMIITIAFDILSRNVEGVGISPFKLFSYSGFCYLPAGL 354
            ..|...:.|.:||.|.||...:.|.:.....:.|:..|..:::|.|:|.:.:....|...|||.|
Human   319 MGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDLQGFGVSIYLIQVIFGAVDLPAKL 383

  Fly   355 TIILFQNKIGRKGMACASLFVGAIITAATGYLVATLDPSDYSVLLGFMVSLGRYGAVVAYDAEAQ 419
            ...|..|.:||:....|:|.:..|.....|.:     |.|.|::...:..||:.....:::....
Human   384 VGFLVINSLGRRPAQMAALLLAGICILLNGVI-----PQDQSIVRTSLAVLGKGCLAASFNCIFL 443

  Fly   420 YAAEIIPTSVKGRGVANIHVVGNAFAFFSSYIIYLGTFYKPLPSLMISFILLIGACLCLALPETL 484
            |..|:.||.::..|:.....:....:..|..:......|..:|..:...:.:..:.:.:.|||||
Human   444 YTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSMTAELYPSMPLFIYGAVPVAASAVTVLLPETL 508

  Fly   485 HKNLPQNLEEGEMFAKGEKWYFFPCFSRRPKTQKSA 520
            .:.||..:::.|              ||...|||.|
Human   509 GQPLPDTVQDLE--------------SRWAPTQKEA 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17751	NP_650816.3	2A0119	11..490	CDD:273328	120/514 (23%)
		MFS	109..481	CDD:119392	89/377 (24%)
SLC22A6	NP_004781.2	2A0119	11..515	CDD:273328	121/515 (23%)
		MFS	135..505	CDD:119392	90/381 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	525..563		4/6 (67%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153823
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.950