DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17751 and HXT5

DIOPT Version :9

Sequence 1:	NP_650816.3	Gene:	CG17751 / 42336	FlyBaseID:	FBgn0038717	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_011964.1	Gene:	HXT5 / 856496	SGDID:	S000001138	Length:	592	Species:	Saccharomyces cerevisiae

Alignment Length:	475	Identity:	112/475 - (23%)
Similarity:	180/475 - (37%)	Gaps:	133/475 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 SFFFIGSALGSIFFGYLADRIGR---LPACVLSTLTG-----ASGD-FFTSFVGSLPWFSFTRFI 164
            |.|.||.|:|.|....|.|..||   |...|:....|     ||.| ::..|:|        |.|
Yeast   141 SIFNIGCAIGGIVLSKLGDMYGRKIGLMTVVVIYSIGIIIQIASIDKWYQYFIG--------RII 197

  Fly   165 SGLFMDTQYVLMYILVFEYLSPQHR-----TFGLNIILGVF--YCVGLMISPWIAIWVTNW--RN 220
            |||.:....||..:|:.|....|.|     .:.|.|..|:|  ||             ||:  :|
Yeast   198 SGLGVGGITVLAPMLISEVSPKQLRGTLVSCYQLMITFGIFLGYC-------------TNFGTKN 249

  Fly   221 Y----LWAASLP-----ALGMLLFPVFLHESAEWLLTKGKFEKAEKSLRGVAKFNGRQVDDSVFD 276
            |    .|...|.     ::.|::...|:.||..:|:..||.|:|::||   |:.|....|..:..
Yeast   250 YSNSVQWRVPLGLCFAWSIFMIVGMTFVPESPRYLVEVGKIEEAKRSL---ARANKTTEDSPLVT 311

  Fly   277 EFIKHYREKLNNSQNKSSDTFMGMLRTPRLRKFTIILLIKSMIITIAFDILSRNVEGVGISPFKL 341
            ..:::|:..: .::..:.....|.|.|.:.:.|...|:  .|:|.....:...|.         .
Yeast   312 LEMENYQSSI-EAERLAGSASWGELVTGKPQMFRRTLM--GMMIQSLQQLTGDNY---------F 364

  Fly   342 FSYSGFCYLPAGL------TIIL---------FQ----NKIGRKG---MACASLFVGAIITAATG 384
            |.|....:...||      .|:|         |.    ::.||:.   ..|..:....::.|:.|
Yeast   365 FYYGTTIFQAVGLEDSFETAIVLGVVNFVSTFFSLYTVDRFGRRNCLLWGCVGMICCYVVYASVG 429

  Fly   385 YLVATLDPS--DYSVLLG-----------FMVSLGRYGAVVAYDAEAQYAAEIIPTSVKGRGVAN 436
              |..|.|:  |.....|           ::.......|.|||    ...:|..|..|:|:.::
Yeast   430 --VTRLWPNGQDQPSSKGAGNCMIVFACFYIFCFATTWAPVAY----VLISESYPLRVRGKAMS- 487

  Fly   437 IHVVGNAFAFFSSYIIYLGTFYKPLPSLMISF---ILLIGACLCLA-------LPETLHKNLPQN 491
               :.:|..:...::|   :|:.|..:..|:|   .:.:| |:..|       :|||  |.|  .
Yeast   488 ---IASACNWIWGFLI---SFFTPFITSAINFYYGYVFMG-CMVFAYFYVFFFVPET--KGL--T 541

  Fly   492 LEE-GEMFA------KGEKW 504
            ||| .||:.      |..||
Yeast   542 LEEVNEMYEENVLPWKSTKW 561

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17751	NP_650816.3	2A0119	11..490	CDD:273328	104/452 (23%)
CG17751	NP_650816.3	MFS	109..481	CDD:119392	99/443 (22%)
HXT5	NP_011964.1	Sugar_tr	89..549	CDD:395036	108/461 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000