Protein Alignment CG17751 and SLC22A16

DIOPT Version :10

• Sequence 1: NP_650816.3
• Gene: CG17751 / 42336
• FlyBaseID: FBgn0038717
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_149116.2
• Gene: SLC22A16 / 85413
• HGNCID: 20302
• Length: 577
• Species: Homo sapiens
• Alignment Length: 589
• Identity: 138/589 - (23%)
• Similarity: 236/589 - (40%)
• Gaps: 88/589 - (14%)

  Fly     4 QSVLEKCGNFGPYQILLLGLFGYTNIVSSLHYFSQTIISFTPSHRCSRP---------------- 52
            :.:.:..|:||.:|.:|..:..:.||...:||.:...:..||.|.|..|
Human     7 EGIYDHVGHFGRFQRVLYFICAFQNISCGIHYLASVFMGVTPHHVCRPPGNVSQVVFHNHSNWSL 71

  Fly    53 -----------EDY-------------------QPNSTSLLSCSVMQFDKEFKCTSWDFERESNY 87
                       :||                   :..:||.|........|||.|.......::.:
Human    72 EDTGALLSSGQKDYVTVQLQNGEIWELSRCSRNKRENTSSLGYEYTGSKKEFPCVDGYIYDQNTW 136

  Fly    88 ESITTELEW--VCDDAYKLAVGQSFFFIGSALGSIFFGYLADRIGRLPACVLSTLTGASGDFF-- 148
            :| |...:|  |||..:...:.|..|..|..|||:.|||.:||:||.   |:...|.:|...|
Human   137 KS-TAVTQWNLVCDRKWLAMLIQPLFMFGVLLGSVTFGYFSDRLGRR---VVLWATSSSMFLFGI 197

  Fly   149 -TSFVGSLPWFSFTRFISGLFMDTQYVLMYILVFEYLSPQHRTFGLNIILGVFYCVGLMISPWIA 212
             .:|......|...||...:......|:.::.|.|::..:.||:. ::.|..|:.||.::.....
Human   198 AAAFAVDYYTFMAARFFLAMVASGYLVVGFVYVMEFIGMKSRTWA-SVHLHSFFAVGTLLVALTG 261

  Fly   213 IWVTNWRNYLWAASLPALGMLLFPVFLHESAEWLLTKGKFEKAEKSLRGVAKFNGRQVDDSVFDE 277
            ..|..|..|....|...:..:|....|.|:..|||::|::|:|:|.:..:||:|  :.......|
Human   262 YLVRTWWLYQMILSTVTVPFILCCWVLPETPFWLLSEGRYEEAQKIVDIMAKWN--RASSCKLSE 324

  Fly   278 FIK-HYREKLNNS-----QNKSSDTFMGMLRTPRLRKFTIILLIKSMIITIAFDILSRNVEGVGI 336
            .:. ..:..::||     ::..|..|.....|.|.....:|....|    :.|...|.|...:|.
Human   325 LLSLDLQGPVSNSPTEVQKHNLSYLFYNWSITKRTLTVWLIWFTGS----LGFYSFSLNSVNLGG 385

  Fly   337 SPFKLFSYSGFCYLPAGLTIILFQNKIGRKGMACASLFVGAIITAATGYLVATLDPSDYSVLLGF 401
            :.:......|...:||...:.:..:|:||:.:...|||..|:   |.|  |..:.|..:.:|...
Human   386 NEYLNLFLLGVVEIPAYTFVCIAMDKVGRRTVLAYSLFCSAL---ACG--VVMVIPQKHYILGVV 445

  Fly   402 MVSLGRYGAVVAYDAEAQYAAEIIPTSVKGRGVANIHVVGNAFAFFSSYIIYLGTFYKPLPSLMI 466
            ...:|::....|:.....|.||:.||.|:...|.:..:|....:..:.:.:.|.:.:..:|.|.:
Human   446 TAMVGKFAIGAAFGLIYLYTAELYPTIVRSLAVGSGSMVCRLASILAPFSVDLSSIWIFIPQLFV 510

  Fly   467 SFILLIGACLCLALPETLHKNLPQNLEEGEMFAKGEKWYFFPCFSRRPKTQK-----SATQLESS 526
            ..:.|:...|.|.|||||.|.|....||.   ||.|.       ....|:.|     :.:.||.:
Human   511 GTMALLSGVLTLKLPETLGKRLATTWEEA---AKLES-------ENESKSSKLLLTTNNSGLEKT 565

  Fly   527 DGIT 530
            :.||
Human   566 EAIT 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17751	NP_650816.3	2A0119	11..490	CDD:273328	127/535 (24%)
SLC22A16	NP_149116.2	MFS_SLC22A16_CT2	118..525	CDD:340933	101/422 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	543..577		7/34 (21%)