DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17751 and oct2

DIOPT Version :9

Sequence 1:	NP_650816.3	Gene:	CG17751 / 42336	FlyBaseID:	FBgn0038717	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_001107932.1	Gene:	oct2 / 797890	ZFINID:	ZDB-GENE-080204-92	Length:	554	Species:	Danio rerio

Alignment Length:	575	Identity:	138/575 - (24%)
Similarity:	243/575 - (42%)	Gaps:	95/575 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 DLQSVLEKCGNFGPYQ----------ILLLGLFGYTNIVSSLHYFSQTIISFTPSH--------- 47
            :...:|:..|:||.||          ||||. |....:|         .:.:||.|
Zfish     3 NFDELLQHAGDFGFYQKRISVLGSLPILLLA-FVLIGVV---------FLGYTPDHWCKTASLQE 57

  Fly    48 ------------------------RCSRPEDYQPNSTSLLSCSVMQFDKEFKCTS----WDFERE 84
                                    :|.:.:|...|. |.|||::..|:.....::    |.|  .
Zfish    58 KCGFSEEQVRDLTVPRTGARGAFSKCVKFDDALRNG-SALSCNISIFNNSTHLSACNEGWTF--N 119

  Fly    85 SNYESITTELEWVCDDAYKLAVGQSFFFIGSALGSIFFGYLADRIGRLPACVLSTL--TGASGDF 147
            .|..:|.||...||:|::...:.|.....|..:|::..||||||.|| .:|.::::  .|.||
Zfish   120 ENRTTIVTEFSLVCEDSWLADLNQVSLAGGFFIGALVTGYLADRFGR-KSCFIASIFGLGVSG-- 181

  Fly   148 FTSFVGS--LPWFSFTRFISGLFMDTQYVLMYILVFEYLSPQHRTFGLNIILGVFYCVGLMISPW 210
             |..:.|  .|...|.|.:.|.|....:...|:|:.|:....:|.| ::::...||.:||::.|.
Zfish   182 -TCIIFSPYYPLLLFFRCLQGFFAKGAWTATYVLIIEFFGSNNRKF-VSVMSRTFYSLGLVLLPA 244

  Fly   211 IAIWVTNWRNYLWAASLPALGMLLFPVFLHESAEWLLTKGKFEKAEKSLRGVAKFNGRQV--DDS 273
            :|.::.:|||...|.:||....|::...:.||..|||::.|.::|...::.:||.|.|.:  |..
Zfish   245 LAYYIPSWRNLQLAMTLPTFIFLIYHWVIPESPRWLLSQRKTKEALSIVKSIAKCNKRSLPEDFH 309

  Fly   274 VFDEFIKHYREKLNNSQNKSSDTFMGMLRTPRLRKFTIILLIKSMIITIAFDILSRNVEGVGISP 338
            ..|..|:...|.:..|       :..:.:||::||.|.||:.......:.|..|...:...|.:.
Zfish   310 EMDLLIEKQEEIMRPS-------YKDLFKTPKMRKHTFILIYAWFTGAVVFQGLVLRLGITGDNV 367

  Fly   339 FKLFSYSGFCYLPAGLTIILFQNKIGRKGMACASLFVGAIITAATGYLVATLDPSDYSVLLGFMV 403
            |..|..|....||.||......::|||:.:.....|:|.....|..::...:     |.|...:.
Zfish   368 FLDFLISAVVELPTGLIFYFLVDRIGRRPLMATVNFIGGAACLAVPFISPNI-----SWLRRTIA 427

  Fly   404 SLGRYGAVVAYDAEAQYAAEIIPTSVKGRGVANIHVVGNAFAFFSSYIIY-LGTFYKPLPSLMIS 467
            .:||....:..:.......|:.||.::..||:......:..|..:.:|:| |.:.::.||.|:..
Zfish   428 IVGRLAVAIGNETVNFANTELYPTPLRNLGVSVCSSASDIGAVVAPFILYRLASIWQELPLLVYG 492

  Fly   468 FILLIGACLCLALPETLHKNLPQNLEEGEMFAKGEKWYFFPCFSRRPKTQKSATQ 522
            .:.::.:.|.:.|||....:||:.:::.|...           ||..:.:|...|
Zfish   493 VMSVLYSGLVMLLPEMKGVDLPETVDDVENLR-----------SRHKRKEKDGAQ 536

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17751	NP_650816.3	2A0119	11..490	CDD:273328	131/532 (25%)
CG17751	NP_650816.3	MFS	109..481	CDD:119392	95/378 (25%)
oct2	NP_001107932.1	2A0119	12..516	CDD:273328	132/533 (25%)
oct2	NP_001107932.1	MFS	123..506	CDD:119392	102/399 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588939
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.950