Protein Alignment CG17751 and Slc22a17

DIOPT Version :10

• Sequence 1: NP_650816.3
• Gene: CG17751 / 42336
• FlyBaseID: FBgn0038717
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_001347335.2
• Gene: Slc22a17 / 59049
• MGIID: 1926225
• Length: 627
• Species: Mus musculus
• Alignment Length: 590
• Identity: 150/590 - (25%)
• Similarity: 241/590 - (40%)
• Gaps: 130/590 - (22%)

  Fly     1 MDLQSVLEKCGNFGPYQILLLGLFGYTNIVSSLHYFSQTIISFTPSHRC---SRPE-----DYQP 57
            :..:::|.:.|..|..|.|.|||.....:..:|...|..|.:..|...|   :.|.     :..|
Mouse    74 LSFEALLAQVGALGGGQQLQLGLCCLPVLFVALGMASDPIFTLAPPLHCHYGALPPNASGWEQPP 138

  Fly    58 NSTSLL--------------------SCSVM---QFDKEFKCTSWDFERESNYESITTEL--EW- 96
            ||:.:.                    |||..   .|:...|  .||:   :....:||..  :|
Mouse   139 NSSGVSVAGAALAASAASGVVTSTDPSCSGFAPPDFNHCLK--DWDY---NGLPVLTTNAIGQWD 198

  Fly    97 -VCDDAYKLAVGQSFFFIGSALGSIFFGYLADRIGRLPACVLSTL-----TGASGDFFTSFVGSL 155
             |||..:::.:.|..|.:|.|.|.:|.||.|||.|| ...||.||     .|..|    :..||.
Mouse   199 LVCDLGWQVILEQILFILGFASGYLFLGYPADRFGR-RGIVLLTLGLVGPCGVGG----AAAGSS 258

  Fly   156 PWFSFTRFISGLFMDTQYVLMYILVFEYLSPQHRTFGLNIIL--------GVFYCVGLMISPWIA 212
            ......||:.|..:....:.:|::..|...|..|   |.:.|        |.|..:||      |
Mouse   259 TGIMALRFLLGFLLAGVDLGVYLMRLELCDPTQR---LRVALAGELVGVGGHFLFLGL------A 314

  Fly   213 IWVTNWRNYLWAASLPALGMLLF--PVFLHESAEWLLTKGKFEKAEKSLRGVAKFN---GRQVDD 272
            :...:||......:.|.:..|.:  |....|||.||:.|.:.|:|:..||.:|:.|   |:.:.:
Mouse   315 LVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVKRQIEEAQSVLRILAERNRPHGQMLGE 379

  Fly   273 SVFDEFIKHYREKLNNSQN------KSSDTFMGMLRTPRLRKFTIILLIKSMIITIAFDILSRNV 331
            ..        :|.|...:|      .|:.:|..:|....:.| .:::|..:..|..|.....:.|
Mouse   380 EA--------QEALQELENTCPLPATSTFSFASLLNYRNIWK-NLLILGFTNFIAHAIRHCYQPV 435

  Fly   332 EGVGI-SPFKLFSY--SGFCYLPA---GLTIILFQNKIGRKGMACASLFVGAIITAATGYLVATL 390
            .|.|. |.|.|.|.  ||...|..   |:|:    ::.||:|:...|:.:..|   |:..|:...
Mouse   436 GGGGSPSDFYLCSLLASGTAALACVFLGVTV----DRFGRRGILLLSMTLTGI---ASLVLLGLW 493

  Fly   391 DPSDYSVLLGFMVSLGRYGAVVAYDAEAQYAAEIIPTSVKGRGVANIHVVGNAFAFFSSYIIYLG 455
            |..:.:.:..|.| ||.:.:..:.......|:|:|||:|:|||:..|..:|           .||
Mouse   494 DYLNDAAITTFSV-LGLFSSQASAILSTLLASEVIPTTVRGRGLGLIMALG-----------ALG 546

  Fly   456 TFYKPLPSLMI---SFI--LLIGAC--LC----LALPETLHKNLPQNLEEGEMFAKGEKWYFFPC 509
            ....|...|.:   :|:  :::.||  ||    :.||||..|.||:.|.:||:..:       |.
Mouse   547 GLSCPAQRLHMGHGAFLQHVVLAACALLCILSIMLLPETKRKLLPEVLRDGELCRR-------PS 604

  Fly   510 FSRRP 514
            ..|:|
Mouse   605 LLRQP 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17751	NP_650816.3	2A0119	11..490	CDD:273328	142/554 (26%)
Slc22a17	NP_001347335.2	MFS_SLC22A17	170..583	CDD:341003	117/459 (25%)