DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17751 and Slc22a17

DIOPT Version :9

Sequence 1:	NP_650816.3	Gene:	CG17751 / 42336	FlyBaseID:	FBgn0038717	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_001347335.1	Gene:	Slc22a17 / 59049	MGIID:	1926225	Length:	520	Species:	Mus musculus

Alignment Length:	525	Identity:	137/525 - (26%)
Similarity:	217/525 - (41%)	Gaps:	118/525 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 SQTIISFTPSHRCS--RPEDYQPNSTSLLSCSVMQFDKEFKCTSWDFERESNYESITTEL--EW- 96
            |..:.|..||  ||  .|.|:.       .|          ...||:   :....:||..  :|
Mouse    49 SGVVTSTDPS--CSGFAPPDFN-------HC----------LKDWDY---NGLPVLTTNAIGQWD 91

  Fly    97 -VCDDAYKLAVGQSFFFIGSALGSIFFGYLADRIGRLPACVLSTL-----TGASGDFFTSFVGSL 155
             |||..:::.:.|..|.:|.|.|.:|.||.|||.|| ...||.||     .|..|    :..||.
Mouse    92 LVCDLGWQVILEQILFILGFASGYLFLGYPADRFGR-RGIVLLTLGLVGPCGVGG----AAAGSS 151

  Fly   156 PWFSFTRFISGLFMDTQYVLMYILVFEYLSPQHRTFGLNIIL--------GVFYCVGLMISPWIA 212
            ......||:.|..:....:.:|::..|...|..|   |.:.|        |.|..:||      |
Mouse   152 TGIMALRFLLGFLLAGVDLGVYLMRLELCDPTQR---LRVALAGELVGVGGHFLFLGL------A 207

  Fly   213 IWVTNWRNYLWAASLPALGMLLF--PVFLHESAEWLLTKGKFEKAEKSLRGVAKFN---GRQVDD 272
            :...:||......:.|.:..|.:  |....|||.||:.|.:.|:|:..||.:|:.|   |:.:.:
Mouse   208 LVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVKRQIEEAQSVLRILAERNRPHGQMLGE 272

  Fly   273 SVFDEFIKHYREKLNNSQN------KSSDTFMGMLRTPRLRKFTIILLIKSMIITIAFDILSRNV 331
            ..        :|.|...:|      .|:.:|..:|....:.| .:::|..:..|..|.....:.|
Mouse   273 EA--------QEALQELENTCPLPATSTFSFASLLNYRNIWK-NLLILGFTNFIAHAIRHCYQPV 328

  Fly   332 EGVGI-SPFKLFSY--SGFCYLPA---GLTIILFQNKIGRKGMACASLFVGAIITAATGYLVATL 390
            .|.|. |.|.|.|.  ||...|..   |:|:    ::.||:|:...|:.:..|   |:..|:...
Mouse   329 GGGGSPSDFYLCSLLASGTAALACVFLGVTV----DRFGRRGILLLSMTLTGI---ASLVLLGLW 386

  Fly   391 DPSDYSVLLGFMVSLGRYGAVVAYDAEAQYAAEIIPTSVKGRGVANIHVVGNAFAFFSSYIIYLG 455
            |..:.:.:..|.| ||.:.:..:.......|:|:|||:|:|||:..|..:|           .||
Mouse   387 DYLNDAAITTFSV-LGLFSSQASAILSTLLASEVIPTTVRGRGLGLIMALG-----------ALG 439

  Fly   456 TFYKPLPSLMI---SFI--LLIGAC--LC----LALPETLHKNLPQNLEEGEMFAKGEKWYFFPC 509
            ....|...|.:   :|:  :::.||  ||    :.||||..|.||:.|.:||:..:       |.
Mouse   440 GLSCPAQRLHMGHGAFLQHVVLAACALLCILSIMLLPETKRKLLPEVLRDGELCRR-------PS 497

  Fly   510 FSRRP 514
            ..|:|
Mouse   498 LLRQP 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17751	NP_650816.3	2A0119	11..490	CDD:273328	130/499 (26%)
CG17751	NP_650816.3	MFS	109..481	CDD:119392	106/412 (26%)
Slc22a17	NP_001347335.1	MFS_SLC22A17	63..476	CDD:341003	118/474 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843387
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030