DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17751 and slc22a13b

DIOPT Version :9

Sequence 1:	NP_650816.3	Gene:	CG17751 / 42336	FlyBaseID:	FBgn0038717	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	XP_017209322.1	Gene:	slc22a13b / 556601	ZFINID:	ZDB-GENE-061013-532	Length:	549	Species:	Danio rerio

Alignment Length:	541	Identity:	126/541 - (23%)
Similarity:	225/541 - (41%)	Gaps:	51/541 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDLQSVLEKCGNFGPYQILLLGLFGYTNIVSSLHYFSQTIISFTPSHRCSR----------PEDY 55
            :|...:|...|.||.:|..||......||.::.|.|.|...:.:..|.|:.          .|:.
Zfish     2 IDFTQILSSVGEFGAFQKRLLVAVCLPNIFTAFHMFGQVFTAISFPHYCNSSWILRQAPNLTEEK 66

  Fly    56 QPNSTSLL-------SCSV---MQFDKE----------FKC-TSWDFERESNYESITTELEWVCD 99
            |.|.|..|       ||.:   ::.|.|          ..| ..|.::...:..::.||.:.||:
Zfish    67 QLNLTVPLDSKGQYESCKMFTPVEMDIEDIEHYGINTTTSCIDGWVYKAPKDSSTLITEFDLVCE 131

  Fly   100 DAYKLAVGQSFFFIGSALGSIFFGYLADRIGRLPACVLSTLTGASGDFFTSFVGSLPWFSFTRFI 164
            :.......||.:..|..:|::.||.:||:.||..|.:||...........:|..::..:...||:
Zfish   132 NKVYSEASQSIYMAGLLVGALLFGPMADKYGRRFATLLSLFLQFLSGVGVAFSPNIYVYIALRFV 196

  Fly   165 SGLFMDTQYVLMYILVFEYLSPQHRTFGLNIILGVFYCVGLMISPWIAIWVTNWRNYLWAASLPA 229
            .|..:....:..::|..|:.....|.. ..|:...|:.:|||:...:|..:.|||......|.|.
Zfish   197 VGTTISGISINTFVLGTEWCGSAKRAL-FTILSHCFFAIGLMLLSGVAYGIRNWRVLQLVLSAPV 260

  Fly   230 LGMLLFPVFLHESAEWLLTKGKFEKAEKSLRGVAKFNGRQVDDSVFDEFIKHYREKLNNSQNKSS 294
            ....::...|.|||.||||:||.:.|::.:...|:.|||:|.:::.|        |:.......|
Zfish   261 GLFFIYYWILPESARWLLTQGKLDSAKREILKAARINGRKVSENLLD--------KMEAENTAKS 317

  Fly   295 DTFMGMLRTPRLRKFTIILLIKSMIITIAFDILSRNVEGVGISPFKLFSYSGFCYLPAGLTIILF 359
            .|.:.:.|...|||..:|:.....:.::.:..:|.||...|:..:......|....||.|:....
Zfish   318 STMIDLFRVGYLRKRALIMCYMWFVTSLVYYGVSLNVGNFGLDIYLTQLIFGMAEFPARLSCFPL 382

  Fly   360 QNKIGRKGMACASLFVGAIITAATGYLVATLDPSDYSVLLGFMVSLGRYGAVVAYDAEAQYAAEI 424
            ..:.||:  .|.|:   .::...|..|:....|:.|.:::..:..:|::....::.....|.||:
Zfish   383 IQRFGRR--ICQSV---VLLLGGTACLIIPAIPAKYPIVVTVIAVIGKFSLAASFSIVYVYTAEL 442

  Fly   425 IPTSVKGRGVANIHVVGNAFAFFSSYIIYLGTFYKPLPSLMISFILLIGACLCLALPETL----- 484
            .||.|:..||....:........:..|..|..::..:|.::...:..:|..|...|||||
Zfish   443 YPTVVRQNGVGLNSMCARVAGILAPLIGLLDVYHHAIPMIIYGSLPFVGGALTFLLPETLNTDLQ 507

  Fly   485 -HKNLPQNLEEGEMFAKGEKW 504
             |.::|.:........|.|:|
Zfish   508 DHTDIPADESMTVTEVKLERW 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17751	NP_650816.3	2A0119	11..490	CDD:273328	120/515 (23%)
CG17751	NP_650816.3	MFS	109..481	CDD:119392	85/371 (23%)
slc22a13b	XP_017209322.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588884
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.950