DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17751 and slc22a15.1

DIOPT Version :9

Sequence 1:	NP_650816.3	Gene:	CG17751 / 42336	FlyBaseID:	FBgn0038717	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	XP_031751719.1	Gene:	slc22a15.1 / 448510	XenbaseID:	XB-GENE-959503	Length:	560	Species:	Xenopus tropicalis

Alignment Length:	559	Identity:	130/559 - (23%)
Similarity:	233/559 - (41%)	Gaps:	74/559 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDLQSVLEKCGNFGPYQI-------LLLGLFGYTNIVSSLHYFSQTIISFTPSHRCSRPEDYQPN 58
            |:::..|:..|..|.|||       :||.|:..|..:..      ||:..||      |..:..:
Frog    27 MEVEGALKLVGEMGIYQIYLSFLLAVLLQLYSATEAIII------TILGATP------PYHWMND 79

  Fly    59 STSLLSCSVMQFDKEFKCTSWDFER-----ESNYESITTELEWVCDDAYKLAVGQSFFFIGSALG 118
            |.:.......|:..:...   :.|.     :.|:.||.:|...|...||:::|..|.:|.|..:|
Frog    80 SLTANGSRGKQYGSQLPA---EGEHGHVVFDGNFTSIVSEWFLVGGAAYEVSVSSSVYFGGVLIG 141

  Fly   119 SIFFGYLADRIGRLPACVLSTLTGASGDFFTSFVGSL----PWFSFTRFISGLFMDTQYVLMYIL 179
            .|.||.|:||.||.|..|    ||.:.:...:.:.:|    |.|..|||:.|:......::.::|
Frog   142 VISFGQLSDRFGRKPVYV----TGLALEVVFAVMNALTPIFPLFLLTRFLVGVMNGGMSLVAFVL 202

  Fly   180 VFEYLSPQHRTFGLNIILGVFYCVGLMISPWIAIWVTNWRNYLWAASLPALGMLLFPVFLHESAE 244
            :.|.:...:.. ....:..:.:.||:.....|..::.:||......::....:|...:.:.||..
Frog   203 LNECIGASYWA-AAGSLGSLCFAVGIAQFALIGYFIRSWRLLALLVNVQGAAVLALSLCIPESPR 266

  Fly   245 WLLTKGKFEKAEKSLRGVAKFNGRQVDDSVFDEFIKHYREKLNNSQNKSSDTFMGMLRTPRLRKF 309
            ||..:|:..:|::||..:.:.|.|:|     ..|....|:|    .:..|...:.:.....||:.
Frog   267 WLHAQGRLREAQESLLSLGRRNRRKV-----TSFTLCPRQK----DSAHSANILTIYSNAILRQR 322

  Fly   310 TIILLIKSMIITIAFDILSRNVEGVGISPFKLFSYSGFCYLPA-GLTIILFQNK-IGRKGMACAS 372
            |:|::....:.::.:..|:.:...:|...:...:.||...||| .|.:.|..:| :||:|.....
Frog   323 TLIMMWVWFVCSLVYYGLTLSSGDLGGDIYLNLALSGLAELPAYPLCMYLINHKRVGRRGSLAGF 387

  Fly   373 LFVGA-------IITAATGYLVATLDPSDYSVLLGFMVS-LGRYGAVVAYDAEAQYAAEIIPTSV 429
            |.||.       ::...||       ....|||....:| ||:.....|::....|::|:.||.|
Frog   388 LCVGGGACLLIMLVPGKTG-------SGPLSVLNSQTLSLLGKLNISAAFNIVYIYSSELYPTCV 445

  Fly   430 KGRGVANIHVVGNAFAFFSSYIIYLGTFYKPLPSLMISFILLIGACLCLALPETLHKNLPQNLEE 494
            :..|:....:........:.:|..|...:..||.::.....:....|.|.|||||...||:.|.:
Frog   446 RNLGMGVCSMFSRIGGIIAPFIPALRFAHWALPFIVFGAAGVSAGLLSLLLPETLSAPLPETLAD 510

  Fly   495 --GEMFAK----GEKWYFFPCFSRRPKTQKSATQLESSD 527
              |..:.:    ||      ....||:.:..|....||:
Frog   511 LRGAPYRRLEPDGE------AMLHRPQAELGAFTNGSSE 543

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17751	NP_650816.3	2A0119	11..490	CDD:273328	118/504 (23%)
CG17751	NP_650816.3	MFS	109..481	CDD:119392	87/385 (23%)
slc22a15.1	XP_031751719.1	MFS	90..497	CDD:421695	97/430 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920