Protein Alignment CG17751 and Slc22a28

DIOPT Version :10

• Sequence 1: NP_650816.3
• Gene: CG17751 / 42336
• FlyBaseID: FBgn0038717
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_001013842.2
• Gene: Slc22a28 / 434674
• MGIID: 3645714
• Length: 552
• Species: Mus musculus
• Alignment Length: 599
• Identity: 139/599 - (23%)
• Similarity: 247/599 - (41%)
• Gaps: 123/599 - (20%)

  Fly     1 MDLQSVLEKCGNFGPYQIL-------LLGLFGYTNIVSSLHYFSQTIISFT---PSHRCSRP--- 52
            |..|.:|.:.|:.|.:|||       |:||     :|..:     |:.:||   |:|||..|
Mouse     1 MAFQELLNQVGSLGRFQILQISFVLFLVGL-----VVPHI-----TMENFTAAIPNHRCWAPILD 55

  Fly    53 -EDYQPNSTSLLS-----------CSVMQFDK--------------------------EFKCTSW 79
             :....|.:.:||           .|.::.||                          |.....|
Mouse    56 NDTASDNGSRILSQDDLLRISIPLDSNLRLDKCRRFAQPQWHLLHLNGTFSNETEPDTEPCVDGW 120

  Fly    80 DFERESNYESITTELEWVCDDAYKLAVGQSFFFIGSALGSIFFGYLADRIGRLPACVLSTLTGAS 144
            .::|.:...:|.||.:.||:.....:|.:..|.||..:|:|..|:|:||.||......:.|..|.
Mouse   121 VYDRSNFLSTIVTEWDLVCESQALNSVAKFSFMIGLFIGAIICGHLSDRFGRKFILTCALLQFAI 185

  Fly   145 GDFFTSFVGSLPWFSFTRFISGLFMDTQYVLMYILVFEYLSPQHRTFGLNIILGVFYC---VGLM 206
            .:...:|..|...:...||::|:.::...|...:|:.|:.:|:.    |.::..:..|   :|.|
Mouse   186 TETCVAFAPSFFIYCLLRFLAGMSVEPISVNSNLLILEWTNPKF----LGMVAVLTSCAASIGYM 246

  Fly   207 ISPWIAIWVTNWRNYLWAASLPALGMLLFPVFLHESAEWLLTKGKFEKAEKSLRGVAKFNG-RQV 270
            |...:|.....|.:...|.|:|.....:...::.|||.||:...|.:|..|.||.||..|| :..
Mouse   247 ILAGLAFLFRIWHHLQLAMSVPIFFFFILTRWMSESARWLIVTNKPQKGLKELRKVAHMNGMKNS 311

  Fly   271 DDSVFDEFIK-HYREKLNNSQNKSS--DTFMGMLRTPRLRKFTIILLIKSMIITIAFDILSRNVE 332
            .:::..|.:: ..:.:|..::.|||  |.|    .||.||....:|.....:.|::...||.:::
Mouse   312 GNTLTMEVVEASMKNELEAAKRKSSPRDLF----HTPILRNRICVLSFMRYLFTVSIFGLSLHLQ 372

  Fly   333 GVGISPFKLFSYSGFCYLPAGLTIIL------FQNKIGRK-----GMACASLFVGAIITAATGYL 386
            .:..:...|      .:|.:.|.|::      ..|.:||:     .|:...:|:          |
Mouse   373 HLSTNIILL------RFLSSALGILISVIGHFVLNHMGRRITQLVLMSLRGIFM----------L 421

  Fly   387 VATLDPSDYSVLLGFMVSLGRYGAVVAYDAEAQYAAEIIPTSVKGRGVANIHVVGNAFAFFSSYI 451
            .|...|.:...|...:|:|....:.:.......:..|::||:::..|:..|.:.||:..|.:...
Mouse   422 TAVFVPQEMQTLRIIVVTLAAALSSLCMCVSNLHINELLPTTLRATGMGVIGMFGNSGLFLAPLF 486

  Fly   452 IYLGTFYKPLPSLMI-SFILLIGACLCLALPETLHKNLPQNLEEGEMFAKGEKWYFFPCFSRRPK 515
            :.|.|:...||.:.. .|.:|.|..:.| ||||.::.||.::.:     .|..|
Mouse   487 MLLATYSANLPWIFYGGFSILYGFSVFL-LPETKNQPLPDSIHD-----VGNDW----------- 534

  Fly   516 TQKSATQLESSDGI 529
              |.:.|.:..|.|
Mouse   535 --KDSRQAKEEDSI 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17751	NP_650816.3	2A0119	11..490	CDD:273328	129/548 (24%)
Slc22a28	NP_001013842.2	MFS_OAT	109..516	CDD:340932	101/431 (23%)