DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17751 and CG6356

DIOPT Version :9

Sequence 1:	NP_650816.3	Gene:	CG17751 / 42336	FlyBaseID:	FBgn0038717	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_651240.1	Gene:	CG6356 / 42893	FlyBaseID:	FBgn0039178	Length:	570	Species:	Drosophila melanogaster

Alignment Length:	560	Identity:	118/560 - (21%)
Similarity:	216/560 - (38%)	Gaps:	96/560 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LQSVLEKCGNFGPYQILLLGLFGYTNIVSSLHYFSQTIISFTPSHR-CSRPEDYQPNSTSLLSCS 66
            |...||..|:.|.:...:..|....||::..|..|.|::...|..: |..||....|.|......
  Fly    24 LTKQLEVVGSGGAFVWAIFFLCVTPNILNGFHVSSYTLLGHLPDDQWCGIPELQDTNWTHAQKRE 88

  Fly    67 VMQFDKEF-KCTSWD----------FERESNYESITTEL-------------------------E 95
            ::....:. .||.||          :|...||....|::                         :
  Fly    89 IVAKGLDSGGCTVWDWNYGHLAKMSYEAALNYTGHLTQISPPAEVSCRVKGQHEFAHPETTFVAD 153

  Fly    96 W--VCDDAYKLAVGQSFFFIGSALGSIFFGYLADRIGRLPACVLSTLTGASGDFFTSFVGSLPWF 158
            |  .||.:.:....|....:|...||..||.|||:.||..:..|.......|.||.:|   .||:
  Fly   154 WDLTCDRSIQRTSAQVSISLGKFCGSFSFGILADKFGRKSSFTLGAAFFIVGSFFCTF---SPWY 215

  Fly   159 SF---TRFISGLFMDTQYVLMYILVFEYLSPQHRTFGLNIILGVFYCVGLMISPWIAIWVTNWRN 220
            |.   .||..|......:...:.::.|.:..:||:: ::|.....|.||::|...:...:..||:
  Fly   216 SLFLAGRFALGAASSGLFYPAFTMIVENICLKHRSW-MSIAFSASYPVGMIILAIVGYVIQPWRH 279

  Fly   221 YLWAASLPALGMLLFPVFLHESAEWLLTKGKFEKAEKSL-RGVAKFNGRQVDDSVF--------- 275
            ...|.::|:|.::|....:.||..||:|..::::..|.| |..:.:   |:..:|.
  Fly   280 LQLALTIPSLLLILNCYLMSESPRWLITNQRYDRVYKILFRQPSHY---QIQPAVAAPSQVASDK 341

  Fly   276 ------DEFIKHYREKLNNSQNKSSDTFMGMLRTPRLRKFTIILLIKSMIITIAFDILSRNVEGV 334
                  :.|  .:.:||.|...||   .:.:....::|:..........:.::::.:.:.|...:
  Fly   342 KSLEPEEGF--SFGQKLKNGPLKS---IIELYANSKVRRMIFASYFMFCVTSLSYYVTALNAANL 401

  Fly   335 GISPFKLFSYSGFCYLPAGLTIILFQNKIGRK----------GMACASLFVGAIITAATGYLVAT 389
            .:|.:.....:|...:|:.|..::.....||:          |::.  |.|.|:...:|.::||
  Fly   402 SVSRYLYIIGTGLVDIPSYLVPVIMLRFTGRRLTTMFLFLWTGVSL--LLVLAVPAGSTTWIVA- 463

  Fly   390 LDPSDYSVLLGFMVSLGRYGAVVAYDAEAQYAAEIIPTSVKGRGVANIHVVGNAFAFFSSYII-Y 453
                        ...|||:|....|.....|.||:.||.::...:.......:..:..:.|:: .
  Fly   464 ------------FAMLGRFGISATYSVVTLYTAELYPTQIRNSALGTCSTFAHVGSISAPYVVDV 516

  Fly   454 LGTFYKPLPSLMISFILLIGACLCLALPETLHKNLPQNLE 493
            ||.....:|:.:....:|:...|.|.||||....|...:|
  Fly   517 LGALGWYIPTTICGCCVLVAGLLTLTLPETGTGKLSDKVE 556

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17751	NP_650816.3	2A0119	11..490	CDD:273328	114/547 (21%)
CG17751	NP_650816.3	MFS	109..481	CDD:119392	83/401 (21%)
CG6356	NP_651240.1	MFS	167..544	CDD:119392	84/403 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458482
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	4	3.940