DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17751 and CG7084

DIOPT Version :9

Sequence 1:	NP_650816.3	Gene:	CG17751 / 42336	FlyBaseID:	FBgn0038717	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_001247235.2	Gene:	CG7084 / 42606	FlyBaseID:	FBgn0038938	Length:	597	Species:	Drosophila melanogaster

Alignment Length:	584	Identity:	140/584 - (23%)
Similarity:	243/584 - (41%)	Gaps:	87/584 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 QSVLEKCGNFGPYQIL----------LLGLFGYTNIVSSLHYFSQTIISFTPSHRCSRP------ 52
            |:::||.||.|.||.|          ..|...|.||:.:|:         .|.|.|:.|
  Fly    35 QALMEKAGNHGRYQTLYNFVFVGGLAFSGAMIYMNIILALN---------IPDHWCTVPGRENTN 90

  Fly    53 --------------------------EDYQPNSTSLLSCSVMQFD----KEFKCTSWDFERESNY 87
                                      |.:|.|.:.:...|....:    .|.....|.:::....
  Fly    91 FSLEEWRDITLPKQADNRGRKTFSNCEMFQMNFSEITDWSAWNSNLTKTTEACQNGWSYDKTWYE 155

  Fly    88 ESITTELEWVCDDAYKLAVGQSFFFIG---SALGSIFFGYLADRIGRLPACVLSTL---TGASGD 146
            .:|.|:..|||  |..|.| .:.|.:|   ...||...|.:.|..||.....:|.:   .|..|.
  Fly   156 STIPTDHNWVC--AKDLFV-TNVFVVGRVTEVAGSFILGQMGDSYGRRFVYYISVVFCSLGRLGS 217

  Fly   147 FFTSFVGSLPWFSFTRFISGLFMDTQYVLMYILVFEYLSPQHRTFGLNIILGVFYCVGLMISPWI 211
            ...:  .|..||.....|.||.:::.:....|:..|....:.|: .:.......:.:|..:.|.:
  Fly   218 IMCT--SSYTWFLIMSGIVGLTVNSLFQSPQIIGMEISREEDRS-RIAFFQSCGWSIGTTLMPLL 279

  Fly   212 AIWVTNWRNYLWAASLPALGMLLFPVFLHESAEWLLTKGKFEKAEKSLRGVAKFNGRQVDDSVFD 276
            ..|:.:|.:::|..|:|...:|||..::.||..||::|.:|.:|...|:.:||.||.:.|.:..:
  Fly   280 YWWLRHWDSFMWLTSIPTAMVLLFSKYVIESPRWLISKQRFREAIVQLQKIAKINGHRFDMTEKE 344

  Fly   277 EFIKHYREKLNNSQNKSSDTFMGMLRTPRLRKFTIILLIKSMIITIAFDIL---SRNVEGVGISP 338
            ....:.|:|.:.:...:| .|.|.    ||.:.|.|:.....::.:::..|   |..:.|   :|
  Fly   345 LAEIYSRDKQDVTYGIAS-LFAGW----RLARNTTIMGFSWCVVAVSYFTLVLFSSRMAG---NP 401

  Fly   339 FKLFSYSGFCYLPAGLTIILFQNKIGRKGMACASLFVGAIITAATGYLVATLDPSDYSVLLGFMV 403
            |..|.|.....:||.:......:..||:.....| |:.:.:|.....:.:|  ...|..|:.::.
  Fly   402 FLNFLYQSIVEIPAYVVGRYMGDTYGRRFTNSVS-FLISFVTCLPIIVYST--DERYENLMIYLA 463

  Fly   404 SLGRY-GAVVAYDAEAQYAAEIIPTSVKGRGVANIHVVGNAFAFFSSYIIYLGTFYK-PLPSLMI 466
            :..:: .|:..:....| ..||.||.::..|||...::.||....:.|::||||... ..|..::
  Fly   464 TFIKFLNALTFFTVNLQ-CLEIYPTCMRQTGVALGTILANAIGVLAPYLVYLGTTVDIRAPYYIL 527

  Fly   467 SFILLIGACLCLALPETLHKNLPQNLEEGEMFAKGEKWYFFPCFSRRPKTQKSATQLESSDGIT 530
            ..:.|:|....|.|||||||.||..:||...|.|.:|::..|   :.|:..:...:|.|...:|
  Fly   528 GVLFLLGGIGALFLPETLHKKLPDTMEEAGHFGKHDKFFSLP---KPPQAAEKDDKLSSHPELT 588

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17751	NP_650816.3	2A0119	11..490	CDD:273328	126/535 (24%)
CG17751	NP_650816.3	MFS	109..481	CDD:119392	89/382 (23%)
CG7084	NP_001247235.2	2A0119	64..552	CDD:273328	120/514 (23%)
CG7084	NP_001247235.2	MFS	184..542	CDD:119392	87/372 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	3	3.010