DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17751 and CG7333

DIOPT Version :9

Sequence 1:	NP_650816.3	Gene:	CG17751 / 42336	FlyBaseID:	FBgn0038717	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_650814.2	Gene:	CG7333 / 42334	FlyBaseID:	FBgn0038715	Length:	541	Species:	Drosophila melanogaster

Alignment Length:	546	Identity:	314/546 - (57%)
Similarity:	411/546 - (75%)	Gaps:	35/546 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDLQSVLEKCGNFGPYQILLLGLFGYTNIVSSLHYFSQTIISFTPSHRCSRPE-----------D 54
            ||...||:||||:|.:|:::|.|:|||||:.||||||||:|:|||.|.|...:           .
  Fly     1 MDFSQVLDKCGNYGRFQVMILLLYGYTNILGSLHYFSQTLITFTPEHWCFHADLNGLSVEGIRSV 65

  Fly    55 YQPNSTSLLSCS----------VMQFDKEFKCTSWDFERESNYESITTELEWVCDDAYKLAVGQS 109
            |:..|.|  ||:          |:..::  ||.:|.|.|||.||||||||:||||.::..|||||
  Fly    66 YENISAS--SCTPLLGVVNGTGVVSTNR--KCRNWIFNRESGYESITTELKWVCDKSHHPAVGQS 126

  Fly   110 FFFIGSALGSIFFGYLADRIGRLPACVLSTLTGASGDFFTSFVGSLPWFSFTRFISGLFMDTQYV 174
            |||:||.:|:|.||||:|::||||:.:::||.||:|||.||||.:||||:|:||:|||..||.|.
  Fly   127 FFFMGSVVGTIIFGYLSDQVGRLPSLLMATLCGATGDFITSFVHTLPWFAFSRFMSGLSTDTMYY 191

  Fly   175 LMYILVFEYLSPQHRTFGLNIILGVFYCVGLMISPWIAIWVTNWRNYLWAASLPALGMLLFPVFL 239
            ||||||||||||:.|||||||||.||||.|||.|||.|||:.|||.|||.|||||||:|::|..:
  Fly   192 LMYILVFEYLSPKSRTFGLNIILAVFYCFGLMTSPWAAIWIGNWRRYLWLASLPALGVLIYPFLI 256

  Fly   240 HESAEWLLTKGKFEKAEKSLRGVAKFNGRQVDDSVFDEFIKHYRE------KLNNSQNKSSDTFM 298
            .|||:|||||.|::.|...|:.|||||.|.|::||||||:|:|||      |||:.:    |||:
  Fly   257 CESAQWLLTKRKYDDAVICLKKVAKFNRRHVEESVFDEFVKYYRERELQDYKLNSHE----DTFL 317

  Fly   299 GMLRTPRLRKFTIILLIKSMIITIAFDILSRNVEGVGISPFKLFSYSGFCYLPAGLTIILFQNKI 363
            .|..|||||:||:.||:||:|||::.|:::||:||:|.|||||||::...|||||:.|:|.||||
  Fly   318 AMFLTPRLRRFTLTLLVKSVIITLSCDVINRNMEGLGTSPFKLFSFTSIVYLPAGVAILLLQNKI 382

  Fly   364 GRKGMACASLFVGAIITAATGYLVATLDPSDYSVLLGFMVSLGRYGAVVAYDAEAQYAAEIIPTS 428
            |||||||.:||||.:||.|||:::|.|||::.::||..||.|||:||.|:||||.||||||||||
  Fly   383 GRKGMACTALFVGGLITTATGFMIAHLDPTENALLLAIMVGLGRFGATVSYDAEIQYAAEIIPTS 447

  Fly   429 VKGRGVANIHVVGNAFAFFSSYIIYLGTFYKPLPSLMISFILLIGACLCLALPETLHKNLPQNLE 493
            |:|:.|:||||:|.|.:..:.|:|||..:||||||:.||.::..||.|||.|||||:|.||:.|.
  Fly   448 VRGQAVSNIHVIGLASSSLAFYVIYLAQYYKPLPSIFISCLMFFGAGLCLTLPETLNKKLPETLA 512

  Fly   494 EGEMFAKGEKWYFFPCFSRRPKTQKS 519
            :||.||..|.:.:||||||:.|..::
  Fly   513 DGEKFALNESFLYFPCFSRKEKNVRT 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17751	NP_650816.3	2A0119	11..490	CDD:273328	294/505 (58%)
CG17751	NP_650816.3	MFS	109..481	CDD:119392	233/377 (62%)
CG7333	NP_650814.2	2A0119	11..510	CDD:273328	295/506 (58%)
CG7333	NP_650814.2	MFS	126..499	CDD:119392	233/376 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471373
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BGEV
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	1	1.010	-	-		D284622at33208
OrthoFinder	1	1.000	-	-		FOG0006714
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	8	7.860