DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17751 and CG8925

DIOPT Version :9

Sequence 1:	NP_650816.3	Gene:	CG17751 / 42336	FlyBaseID:	FBgn0038717	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_650526.1	Gene:	CG8925 / 41963	FlyBaseID:	FBgn0038404	Length:	670	Species:	Drosophila melanogaster

Alignment Length:	525	Identity:	113/525 - (21%)
Similarity:	203/525 - (38%)	Gaps:	107/525 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDL--QSVLEK-CGNFGPYQILLLGLFGYTNIVSSLHYFSQTIISFTPSHRCSRPEDYQPNSTS- 61
            :||  ..:||: .|...|:|.:...|......:.:.|.|............|:|||:....|.|
  Fly   142 LDLLHTKLLERLLGCLTPWQSMWCALLSIFQAICTFHIFVYVFQIAPKDFWCARPENLMQMSVSE 206

  Fly    62 ------------LLSCSVMQFDKE----------------FKCTSWDFE---RESNYESITTELE 95
                        ||.....|...|                .:|  |.||   .:.:.:::..|.:
  Fly   207 WRNISQSSNGCLLLDVDYTQVTYENNQLINWPENATDLGYRQC--WHFEFSDVDGSAKTLVQEFD 269

  Fly    96 WVCDDAYKLAVGQSFFFIGSALGSIFFGYLADRIGR---LPACVLSTLTGASGDFFTSFVGSLPW 157
            .||.... |::.::.|.:|:|.|::..|:::||.||   |.|.|  |:....|... :|..|:..
  Fly   270 LVCGRDI-LSLVETCFLVGAAAGAVLSGWISDRFGRRHTLMAFV--TIQSVFGGIL-AFSTSVAM 330

  Fly   158 FSFTRFISGLFMDTQYVLMYILVFEYLSPQHRT-FGLNIILGVFYCVGLMISPWIAIWVTNWRNY 221
            |...|.|.|....|..|:.::||.|.:|.:.|| .|:..||.|  .:..::|..:|..:.:||:.
  Fly   331 FMSLRVIIGFASMTVTVVSFVLVVELVSGKWRTVIGILNILPV--AISYVLSAGLAYLIRDWRHL 393

  Fly   222 LWAASLPALGMLLFPVFLHESAEWLLTKGKFEKAEKSLRGVAKFNG---------RQVDDSVFDE 277
            ..|.|.|.|.||....:|.||..|||.:|:.::....:...|:.||         |:..::....
  Fly   394 QLAISWPWLIMLSIWFWLPESPRWLLAQGRLDELCGLIERAARMNGTSASLPSNYRKTLEAAVPR 458

  Fly   278 FIKHYREKLNNSQNKSSDT-------------FMGMLRTPRLRKFTIILLIKSMIITIAFDI--- 326
            .::...|...:.::|:.:.             .:.:......|...:.|:|...:|.|.|.:
  Fly   459 AVQSPPEATTSVESKAVEADAPDPSASGHVNPLLVVFSAKYWRTTCLTLVIWLTLIIIYFGLTLH 523

  Fly   327 -------------LSRNVEGVGISPFKLF--------SYSGFCYLPAGLTII---LFQNKIGRKG 367
                         ::..||.:.|....|.        |..|:..|| ||..:   |..|:.|...
  Fly   524 LSNLGGNIYINSAVAGTVEAISICISILVVLKVGIRRSLIGYMLLP-GLCCLATNLVSNQTGVIA 587

  Fly   368 MACASLFVGAIITAATGYLVATLDPSDY-SVLLGFMVSLGRYGA-----VVAYDAEAQYAAEIIP 426
            :|.    :...:..|...::.|.....| :::..|.|.:|...:     :|.:..:.::...::|
  Fly   588 LAT----IAKCLIGANNAIIPTYTAMQYPTIVRNFGVGMGNLASGIALILVPFLWKLEHIDPLLP 648

  Fly   427 TSVKG 431
            .:|.|
  Fly   649 LNVMG 653

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17751	NP_650816.3	2A0119	11..490	CDD:273328	109/512 (21%)
CG17751	NP_650816.3	MFS	109..481	CDD:119392	85/382 (22%)
CG8925	NP_650526.1	MFS	277..667	CDD:119392	86/387 (22%)
CG8925	NP_650526.1	MFS_1	277..635	CDD:284993	82/367 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	3	3.010