DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17751 and CG6006

DIOPT Version :9

Sequence 1:	NP_650816.3	Gene:	CG17751 / 42336	FlyBaseID:	FBgn0038717	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_001097812.1	Gene:	CG6006 / 41962	FlyBaseID:	FBgn0063649	Length:	603	Species:	Drosophila melanogaster

Alignment Length:	530	Identity:	114/530 - (21%)
Similarity:	207/530 - (39%)	Gaps:	79/530 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 GNFGPYQILLLGLFGYTNIVSSLHYFSQTIISFTPSHRCSRPEDYQ------------------- 56
            |::|.:|:|:..|.....:.::.|..|....:......|.||...|
  Fly    90 GHYGKWQLLMTVLLSLFQVPNTFHISSSIYQAANKDFWCQRPAQLQHMPVATWRNLSGSVDNCRR 154

  Fly    57 ---------PNSTSLLS--CSVMQFDKEF-KCTSWDFERESNY-ESITTELEWVCDDAYKLAVGQ 108
                     .|.|:|.|  .:..:.||:. .|..|::|...|. .:.|::.:.||:..:...|.:
  Fly   155 WEGIDWSQVSNETTLPSDWKTPAEMDKKLVACEKWEYETNDNVGNTWTSQWDLVCEKEHLKNVAE 219

  Fly   109 SFFFIGSALGSIFFGYLADRIGR----LPACVLSTLTG------ASGDFFTSFVGSLPWFSFTRF 163
            .||.:|.|.|.|..|||:|:.||    ..:.||.|:.|      :|.:.:.:....|...|.:..
  Fly   220 MFFLLGVATGGIISGYLSDKFGRKTMLFISAVLQTIFGLWLYICSSFELYLTLRALLGLVSVSVT 284

  Fly   164 ISGLFMDTQYVLMYILVFEYLSPQHRTFGLNIILGVFYC----VGLMISPWIAIWVTNWRNYLWA 224
            .|||          ||..||:..:.||     |.|::..    :..||...:|....:::.....
  Fly   285 YSGL----------ILAIEYVDGKWRT-----IAGMYNLFPLPISYMIISGLAYLTQDYQRLQLC 334

  Fly   225 ASLPALGMLLFPVFLHESAEWLLTKGKFEKAEKSLRGVAKFNGRQVDDSVFDEFIKHYREKLNNS 289
            ..:|.:.:......:.||..|||.||:.::..:.:...|||||||:....         :....:
  Fly   335 IGIPGIFLCFLWFVVPESPRWLLVKGRIDEVRRIIEAAAKFNGRQLPADY---------QLTPPT 390

  Fly   290 QNKSSDTFMGMLRTPRLRKFTIILLIKSMIITIAFDILSRNVEGVGISPFKLFSYSGFCYLPAGL 354
            |..|:.....:.|:..||:.:|........:.:.:..:..|:...|.:.:...:.:|...:||..
  Fly   391 QESSTQDVTYLFRSSYLRRISICFFCIWFTMNLVYYGIILNMSSFGGNVYLNSALAGLVEIPAIA 455

  Fly   355 TIILFQNKIGRKGMACASLFVGAIITAATGYLVATLDPSDYSVL---LGFMVSLGRYGAVVAYDA 416
            ..:....|:|:|.:.||:|     |.|......|.:......:|   :.|:: :|::........
  Fly   456 VAMYIITKVGKKWLFCATL-----ICAGVACCCAAITEGHADLLWLKITFLM-MGKFTISAGNTI 514

  Fly   417 EAQYAAEIIPTSVKGRGVANIHVVGNAFAFFSSYIIYLGTFYKPLPSLMISFILLIGACLCLALP 481
            ...|.||:.||.::..||...:|........:.|:..|......|...:::...:.|..:.|.||
  Fly   515 MPVYTAELYPTPIRNVGVGACNVAAGLALILTPYLSLLNKIEGHLLMTLLTAWSIFGGFVVLFLP 579

  Fly   482 ETLHKNLPQN 491
            ||..:....|
  Fly   580 ETAVRQKTDN 589

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17751	NP_650816.3	2A0119	11..490	CDD:273328	113/527 (21%)
CG17751	NP_650816.3	MFS	109..481	CDD:119392	84/388 (22%)
CG6006	NP_001097812.1	2A0119	90..581	CDD:273328	111/520 (21%)
CG6006	NP_001097812.1	MFS	222..579	CDD:119392	83/386 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	3	3.010