DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17751 and CG14857

DIOPT Version :9

Sequence 1:	NP_650816.3	Gene:	CG17751 / 42336	FlyBaseID:	FBgn0038717	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_650392.1	Gene:	CG14857 / 41791	FlyBaseID:	FBgn0038262	Length:	560	Species:	Drosophila melanogaster

Alignment Length:	544	Identity:	198/544 - (36%)
Similarity:	312/544 - (57%)	Gaps:	25/544 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDLQSVLEKCGNFGPYQILLLGLFGYTNIVSSLHYFSQTIISFTPSHRCSRPEDYQPNSTSLLSC 65
            ||...:|||||:.|.||.|::.|.||....:::||:||.||.|.|.|.|.. |..:..|...::.
  Fly     1 MDFDQILEKCGSAGRYQYLMILLLGYIAFTTTVHYYSQNIIGFVPQHWCYH-EALENRSFEEIAA 64

  Fly    66 SVMQFDKEFKCT------------------SWDFERESNYESITTELEWVCDDAYKLAVGQSFFF 112
            ....|.||..||                  .|.:..:..:.|:..||.|||:||||..:|||.||
  Fly    65 IYAPFGKEASCTRLDKIEGDRVTVSNETCQRWIYNYDFGFRSMNAELNWVCNDAYKARIGQSLFF 129

  Fly   113 IGSALGSIFFGYLADRIGRLPACVLSTLTGASGDFFTSFVGSLPWFSFTRFISGLFMDTQYVLMY 177
            :||.:|:..||.|.|||||:.|.:|:...|..|||.|::..:|..|:..|.||||.....|.||:
  Fly   130 LGSLMGTFTFGVLGDRIGRVRAVILANQCGFVGDFLTTYASNLVQFAIFRCISGLAATANYYLMF 194

  Fly   178 ILVFEYLSPQHRTFGLNIILGVFYCVGLMISPWIAIWVTNWRNYLWAASLPALGMLLFPVFLHES 242
            |||.|||:|:.|...::..||:.:|:|.:::||:::...|||.||..::|..|.:.||...:.||
  Fly   195 ILVLEYLAPKLRNMAISGTLGICFCLGALVAPWLSVLAGNWRIYLTCSALLQLVVALFYFVVQES 259

  Fly   243 AEWLLTKGKFEKAEKSLRGVAKFNGRQVDDSVFDEFIKH--YREKLNNSQNKSSDTFMGMLRTPR 305
            |:||:|:...|.|...|:.:|.|||.:|..:.|:.|.::  .:.||:|...:::..| .:||||.
  Fly   260 AQWLITRTNVEGAIARLKHIAHFNGMEVKAADFEAFRRNCIVKRKLSNQPEQTAGIF-DLLRTPN 323

  Fly   306 LRKFTIILLIKSMIITIAFDILSRNVEGVGISPFKLFSYSGFCYLPAGLTIILFQNKIGRKGMAC 370
            |||.:::::...|:.:::|:.:||||||:|:|||.:||.......|:|....|.|:::|||..|.
  Fly   324 LRKVSLLVVFTFMLTSLSFNTISRNVEGMGLSPFVVFSLFAVVVPPSGFIQGLLQSRVGRKATAF 388

  Fly   371 ASLFVGAIITAATGYLVATLD-PSDYSVLLGFMVSLGRYGAVVAYDAEAQYAAEIIPTSVKGRGV 434
            .::....:::.|.|..::|.. ..:.::||.|.:.: |.|..:.|...:|:|:|::||.|:.||:
  Fly   389 LAMLCTGLLSCALGVALSTEGAQKNVTLLLAFALPM-RLGISMCYTVTSQFASELLPTCVRSRGI 452

  Fly   435 ANIHVVGNAFAFFSSYIIYLGTFYKPLPSLMISFILLIGACLCLALPETLHKNLPQNLEEGEMFA 499
            |.:|:.....:|.|.|:|:|||.....|||:::.:||..:...|.||||.::.||..|.:||.|.
  Fly   453 AAVHLAAAGASFVSPYLIHLGTKLAAAPSLILALLLLTASGCTLMLPETNNRQLPITLADGEAFG 517

  Fly   500 KGEKWYFFPCFSRR-PKTQKSATQ 522
            |||....|.|:.|. ....|.||:
  Fly   518 KGESMLSFDCWRRHDDDVSKEATE 541

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17751	NP_650816.3	2A0119	11..490	CDD:273328	178/499 (36%)
CG17751	NP_650816.3	MFS	109..481	CDD:119392	135/374 (36%)
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	179/500 (36%)
CG14857	NP_650392.1	MFS	126..470	CDD:119392	125/345 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471385
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BGEV
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	1	1.010	-	-		D284622at33208
OrthoFinder	1	1.000	-	-		FOG0006714
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	8	7.860