DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17751 and CG14855

DIOPT Version :9

Sequence 1:	NP_650816.3	Gene:	CG17751 / 42336	FlyBaseID:	FBgn0038717	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_650390.2	Gene:	CG14855 / 41789	FlyBaseID:	FBgn0038260	Length:	556	Species:	Drosophila melanogaster

Alignment Length:	559	Identity:	230/559 - (41%)
Similarity:	330/559 - (59%)	Gaps:	32/559 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDLQSVLEKCGNFGPYQILLLGLFGYTNIVSSLHYFSQTIISFTPSHRCSRPEDYQPNSTSLLSC 65
            ||.:.:|.||||...||.:||.|:||..:|.|:|||||.:|||.|.|.|.. |..:..|.:.:..
  Fly     1 MDFEEILAKCGNSSRYQFVLLALYGYLMVVVSMHYFSQNVISFVPDHWCYH-EQLENRSFAEIEK 64

  Fly    66 SVMQFDK-------------------EFKCTSWDFERESNYESITTELEWVCDDAYKLAVGQSFF 111
            ...||:|                   ..:|..|.::.:..|:|:.|||.||||:|||..||||.|
  Fly    65 IYSQFEKPSCTRLEKIDEDGQNHTLSRERCNRWIYKYDFGYKSMNTELNWVCDEAYKARVGQSLF 129

  Fly   112 FIGSALGSIFFGYLADRIGRLPACVLSTLTGASGDFFTSFVGSLPWFSFTRFISGLFMDTQYVLM 176
            |:||..|::.||.|.|||||:.|.:|:...|..|||.|.|.|||..||.:||||||..|....||
  Fly   130 FVGSVCGTLAFGLLGDRIGRIRALILANWCGFLGDFSTIFAGSLTSFSISRFISGLAADANSYLM 194

  Fly   177 YILVFEYLSPQHRTFGLNIILGVFYCVGLMISPWIAIWVTNWRNYLWAASLPALGMLLFPVFLHE 241
            |||:.||:||..|..|||.:||.|||:||:.:.|:|:||.:||.:|..:|:|.|.:.||...:.|
  Fly   195 YILILEYVSPSLRNVGLNTVLGSFYCLGLIGACWLAVWVGHWRIFLACSSVPLLLVTLFYFLVQE 259

  Fly   242 SAEWLLTKGKFEKAEKSLRGVAKFNGRQVDDSVFDEF----IKHYREKLNNSQNKSSDTFMGMLR 302
            ||:||:|:...:.|.:.|..|||.|.|||.|..|.:|    .:|||:..|..::..   .:.||:
  Fly   260 SAQWLVTRNDVDGAIRRLERVAKINRRQVADKDFKDFRIYCEQHYRKDKNQEEHAK---LLDMLK 321

  Fly   303 TPRLRKFTIILLIKSMIITIAFDILSRNVEGVGISPFKLFSYSGFCYLPAGLTIILFQNKIGRKG 367
            |||:|.....||:..:||...::.::|||||:|||||.:||.:.....|:|....|.|:::|||.
  Fly   322 TPRMRSTAFKLLLIFIIIVPCYNTIARNVEGLGISPFIMFSLNALTLPPSGYLQGLLQDRMGRKA 386

  Fly   368 MACASLFVGAIITAATGYLVATLDPSDYSVLLGFMVSLGRYGAVVAYDAEAQYAAEIIPTSVKGR 432
            .|...:.:..|...|.|.:::.....:..:|:|..:: .|:|..:|..|.:|::.|:|||||:||
  Fly   387 TAVGWMAITGIFAVAAGLVISQGSNRNVLLLVGLTMA-ARFGVSIADGASSQFSTELIPTSVRGR 450

  Fly   433 GVANIHVVGNAFAFFSSYIIYLGTFYKPLPSLMISFILLIGACLCLALPETLHKNLPQNLEEGEM 497
            |||.:||.|.|.:|.|.||::|||:|||.||:::..:.|.||.:||.||||.:|.||.:|.|||.
  Fly   451 GVAVVHVAGFAASFLSPYILHLGTYYKPAPSIILGLLFLSGAYVCLLLPETRNKKLPMSLAEGEE 515

  Fly   498 FAKGEKWYFFPCFSRRPKTQKSATQ----LESSDGITNK 532
            |.:||..:.|.....|.:..||..:    :...|.:.||
  Fly   516 FGRGEGIFDFLRHMFRREGSKSEVEMGPTIVEEDTLINK 554

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17751	NP_650816.3	2A0119	11..490	CDD:273328	210/501 (42%)
CG17751	NP_650816.3	MFS	109..481	CDD:119392	160/375 (43%)
CG14855	NP_650390.2	2A0119	11..507	CDD:273328	209/500 (42%)
CG14855	NP_650390.2	MFS	127..499	CDD:119392	160/375 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471387
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BGEV
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	1	1.010	-	-		D284622at33208
OrthoFinder	1	1.000	-	-		FOG0006714
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	8	7.860