DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17751 and F23F12.13

DIOPT Version :9

Sequence 1:	NP_650816.3	Gene:	CG17751 / 42336	FlyBaseID:	FBgn0038717	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_001033356.1	Gene:	F23F12.13 / 3896740	WormBaseID:	WBGene00044455	Length:	528	Species:	Caenorhabditis elegans

Alignment Length:	517	Identity:	121/517 - (23%)
Similarity:	184/517 - (35%)	Gaps:	123/517 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 SLHYFSQTIIS----FTPSHRCSRPEDYQPNSTSLLSCSVMQFDKEFKCTSWDFERESNYESITT 92
            :|.:..|.|.|    |:|...|..|..........||.|.:..:....|:....| |:.:.|:..
Worm    20 ALFFCCQQIFSIFYNFSPGLSCDDPSFQFSKPKCKLSKSEICSELTANCSKIVIE-EAPFHSMVQ 83

  Fly    93 ELEWVC-DDAYKLAVGQSFFFIGSALGSIFFGYLADRIGRLPACVLSTLTGASGDFFTSFVGSLP 156
            :.:..| ..||..|...:..|||..:|:|.:|:|.|..||.|........|......:.|..|..
Worm    84 DFKMFCGTKAYDAAWVATIQFIGVLIGAITYGHLGDHFGRKPVSFFGISVGILFGVASGFAPSWE 148

  Fly   157 WFSFTRFISGLFMDTQYVLMYILVFEYLSPQHRTF----------GLNIILGVFYCVGLMISPWI 211
            .|:..|||.|..:.:..::.|..:.|::.|:.|.|          .|...|..|.|
Worm   149 VFAAFRFIVGTSIASILIVFYAYILEFIEPEQRVFLRSFFNWGYARLVFTLACFIC--------- 204

  Fly   212 AIWVTNWRNYLWAASLPALGMLLFPVFLHESAEWLLTKGKFEKAEKSLRGVAKFNG-RQVDDSVF 275
                ..||:...|.||.:|.:|...:.|.||.:|..||.:|..|..:.:.||..:| ..|:|.
Worm   205 ----GYWRSAAIATSLLSLPILPVLLILPESPKWFNTKKRFRDARAAEKRVAWLSGIPYVNDE-- 263

  Fly   276 DEFIKHYREKLNNSQNK---SSDTFMGMLRTPRLRKFTII---LLIKSMIITIAFDILSRNVEGV 334
            |:.|: ..|||.....|   ..|.|.......|    ||:   |...:.:.....|:.|.|:
Worm   264 DQSIE-ISEKLEEKSTKIYTMKDLFTSWTIAYR----TIVVGSLWFSTSLSAFGSDLNSGNL--- 320

  Fly   335 GISPFKLFSYSGFCYLPAGLTIILFQNKIGRKGMACASLFVGAIITAATGYLVATLD---PS--- 393
                      :|..||                     |.||...:||.....|..||   ||
Worm   321 ----------AGNFYL---------------------SQFVSGAVTAFAKIFVFLLDTYVPSFDR 354

  Fly   394 -------------DYSVLLGFMV----SLGRYGA----------------VVAYDAEAQYAAEII 425
                         .|.|::..|:    ..|..|:                .:.:||....|.|..
Worm   355 RRLHQYPQIAMILCYCVIMVLMILPESDCGSQGSRDLAIIIINIIGVSFIEITWDACYLVAVECF 419

  Fly   426 PTSVKGRGVANIHVVGNAFAFFSSYIIYLGTFYKPLPSLMISFI----LLIGACLCLALPET 483
            ||.::..|:....::....|..:..:.||...|:|.|..::..|    |||.   |:.||:|
Worm   420 PTKIRTIGIGTCSLLARTGALLAPQMAYLSDIYRPAPYAVVCSIGTISLLIS---CVFLPDT 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17751	NP_650816.3	2A0119	11..490	CDD:273328	121/517 (23%)
CG17751	NP_650816.3	MFS	109..481	CDD:119392	99/431 (23%)
F23F12.13	NP_001033356.1	MFS	74..476	CDD:391944	106/459 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163124
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.850