Protein Alignment CG17751 and SLC22A10

DIOPT Version :9

• Sequence 1: NP_650816.3
• Gene: CG17751 / 42336
• FlyBaseID: FBgn0038717
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_001034841.3
• Gene: SLC22A10 / 387775
• HGNCID: 18057
• Length: 541
• Species: Homo sapiens
• Alignment Length: 561
• Identity: 135/561 - (24%)
• Similarity: 226/561 - (40%)
• Gaps: 81/561 - (14%)

  Fly     1 MDLQSVLEKCGNFGPYQILLLGLFGYTNIVSSL-----HYFSQTIISFTPSHRC----SRPEDYQ 56
            |..:.:|.:.|..|.:|:|.| :|    |:.||     |...:...:..|.|||    .......
Human     1 MAFEELLSQVGGLGRFQMLHL-VF----ILPSLMLLIPHILLENFAAAIPGHRCWVHMLDNNTGS 60

  Fly    57 PNSTSLLS-------------------C------------------SVMQFDKEFKCTSWDFERE 84
            .|.|.:||                   |                  |..:.|.|.....|.:::.
Human    61 GNETGILSEDALLRISIPLDSNLRPEKCRRFVHPQWQLLHLNGTIHSTSEADTEPCVDGWVYDQS 125

  Fly    85 SNYESITTELEWVCDDAYKLAVGQSFFFIGSALGSIFFGYLADRIGR---LPACVLSTLTGASGD 146
            ....:|.|:.:.|||.....:|.|.....|..:|.|..|:::||.||   |..|:|..   |..|
Human   126 YFPSTIVTKWDLVCDYQSLKSVVQFLLLTGMLVGGIIGGHVSDRFGRRFILRWCLLQL---AITD 187

  Fly   147 FFTSFVGSLPWFSFTRFISGLFMDTQYVLMYIL------VFEYLSPQHRTFGLNIILGVFYCVGL 205
            ...:|..:.|.:...||::|      :..|.|:      :.|::.|..:...:.:..|.. .:|.
Human   188 TCAAFAPTFPVYCVLRFLAG------FSSMIIISNNSLPITEWIRPNSKALVVILSSGAL-SIGQ 245

  Fly   206 MISPWIAIWVTNWRNYLWAASLPALGMLLFPVFLHESAEWLLTKGKFEKAEKSLRGVAKFNG-RQ 269
            :|...:|....:|:.....||:|.....|...:|.|||.||:...|.::..|:||.||:.|| :.
Human   246 IILGGLAYVFRDWQTLHVVASVPFFVFFLLSRWLVESARWLIITNKLDEGLKALRKVARTNGIKN 310

  Fly   270 VDDSVFDEFIKH-YREKLNNSQNKSSDTFMGMLRTPRLRKFTIILLIKSMIITIAFDILSRNVEG 333
            .::::..|.::. .:|:|:.:|.|:  |...:.|.|.:||...||:......||.|.....|::.
Human   311 AEETLNIEVVRSTMQEELDAAQTKT--TVCDLFRNPSMRKRICILVFLRFANTIPFYGTMVNLQH 373

  Fly   334 VGISPFKLFSYSGFCYLPAGLTIILFQNKIGRKGMACASLF-VGAIITAATGYLVATLDPSDYSV 397
            ||.:.|.|....|...|......:|..|.:||:......:| ||..|      |..|..|.:...
Human   374 VGSNIFLLQVLYGAVALIVRCLALLTLNHMGRRISQILFMFLVGLSI------LANTFVPKEMQT 432

  Fly   398 LLGFMVSLGRYGAVVAYDAEAQYAAEIIPTSVKGRGVANIHVVGNAFAFFSSYIIYLGTFYKPLP 462
            |...:..||...:...:.:.|.:..|:|||.::.|............|..:..::.|..|:..||
Human   433 LRVALACLGIGCSAATFSSVAVHFIELIPTVLRARASGIDLTASRIGAALAPLLMTLTVFFTTLP 497

  Fly   463 SLMISFILLIGACLCLALPETLHKNLPQNLEEGEMFAKGEK 503
            .::.....:||..:...||||.:..||..:::.|...|..|
Human   498 WIIYGIFPIIGGLIVFLLPETKNLPLPDTIKDVENQKKNLK 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17751	NP_650816.3	2A0119	11..490	CDD:273328	129/536 (24%)
		MFS	109..481	CDD:119392	94/383 (25%)
SLC22A10	NP_001034841.3	2A0119	11..526	CDD:273328	130/537 (24%)
		MFS	143..516	CDD:119392	96/390 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153701
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.940