Protein Alignment CG17751 and SLC22A25

DIOPT Version :9

• Sequence 1: NP_650816.3
• Gene: CG17751 / 42336
• FlyBaseID: FBgn0038717
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: XP_016873173.1
• Gene: SLC22A25 / 387601
• HGNCID: 32935
• Length: 577
• Species: Homo sapiens
• Alignment Length: 576
• Identity: 129/576 - (22%)
• Similarity: 219/576 - (38%)
• Gaps: 95/576 - (16%)

  Fly     1 MDLQSVLEKCGNFGPYQILLLGLFGYTNIVSSLHYFSQTIISFTPSHRC-------SRPEDYQPN 58
            |..|.:|::.|..|.:|||.:......|::.......:...:|...|||       ....|..|.
Human     1 MAFQDLLDQVGGLGRFQILQMVFLIMFNVIVYHQTQLENFAAFILDHRCWVHILDNDTIPDNDPG 65

  Fly    59 STS---LLSCSVMQFDKEF---KC-------------------TS----------WDFERESNYE 88
            :.|   ||..|: .||...   ||                   ||          |.:::.|...
Human    66 TLSQDALLRISI-PFDSNLRPEKCRRFVHPQWKLIHLNGTFPNTSEPDTEPCVDGWVYDQSSFPS 129

  Fly    89 SITTELEWVCDDAYKLAVGQSFFFIGSALGSIFFGYLADR------------------------- 128
            :|.|:.:.||:.....:|.:..|..|..:|...:|:|:||
Human   130 TIVTKWDLVCESQPLNSVAKFLFMAGMMVGGNLYGHLSDRKPLSSPNHVSTDCDEGLEVPIAIHQ 194

  Fly   129 -----IGRLPACVLSTLTGASGDFFTSFVGSLPWFSFTRFISGLFMDTQYVLMYILVFEYLSPQH 188
                 .||......|.|..|......:|..::..:...||::|....:..|...:|:.|:::.|.
Human   195 HHVFWFGRKFVLRWSYLQLAIVGTCAAFAPTILVYCSLRFLAGAATFSIIVNTVLLIVEWITHQF 259

  Fly   189 RTFGLNIILGVFYC---VGLMISPWIAIWVTNWRNYLWAASLPALGMLLFPVFLHESAEWLLTKG 250
            ....|.:.|    |   :|.:....:|..:.:........|.|.....||..:|.|||.||:...
Human   260 CAMALTLTL----CAASIGHITLGSLAFVIRDQCILQLVMSAPCFVFFLFSRWLAESARWLIINN 320

  Fly   251 KFEKAEKSLRGVAKFNG-RQVDDSVFDEFIKH-YREKLNNSQNKSSDTFMGMLRTPRLRKFTIIL 313
            |.|:..|.||..|..|| :..:|.:..|.:|. .:::|..:|.|.|  ...:||.|.:.|....|
Human   321 KPEEGLKELRKAAHRNGMKNAEDILTMEVLKSTMKQELEAAQKKHS--LCELLRIPNICKRICFL 383

  Fly   314 LIKSMIITIAFDILSRNVEGVGISPFKLFSYSGFCYLPAGLTIILFQNKIGRKGMACASLFVGAI 378
            .......||.|..|:.:::.:|.:.|.|.:..|...|.|........|.:.|:......:|:
Human   384 SFVRFASTIPFWGLTLHLQHLGNNVFLLQTLFGAVTLLANCVAPWALNHMSRRLSQMLLMFL--- 445

  Fly   379 ITAATGYLVATLDPSDYSVLLGFMVSLGRYGAVVAYDAEAQYAAEIIPTSVKGRG---VANIHVV 440
              .||..|.....|.:...|...:.:||...|.:..........|:||:.::||.   ..|...:
Human   446 --LATCLLAIIFVPQEMQTLRVVLATLGVGAASLGITCSTAQENELIPSIIRGRATGITGNFANI 508

  Fly   441 GNAFAFFSSYIIYLGTFYKPLPSLMISFILLIGACLCLALPETLHKNLPQNLEEGE 496
            |.|.|   |.::.|..:.:|||.::.....::...:.|.||||.::.|..::::.|
Human   509 GGALA---SLMMILSIYSRPLPWIIYGVFAILSGLVVLLLPETRNQPLLDSIQDVE 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17751	NP_650816.3	2A0119	11..490	CDD:273328	125/558 (22%)
		MFS	109..481	CDD:119392	91/409 (22%)
SLC22A25	XP_016873173.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153673
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5187
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.890