DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17751 and CarT

DIOPT Version :9

Sequence 1:	NP_650816.3	Gene:	CG17751 / 42336	FlyBaseID:	FBgn0038717	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_610052.1	Gene:	CarT / 35334	FlyBaseID:	FBgn0032879	Length:	674	Species:	Drosophila melanogaster

Alignment Length:	585	Identity:	156/585 - (26%)
Similarity:	252/585 - (43%)	Gaps:	81/585 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 DLQSVLEKCGNFGPYQ-ILLLGLFGYTNIVSSLHYFSQTIISFTP-SHRCSRPE----------- 53
            ||..:|...|.||.|| :|:.|:.....|......|:|..::.|| .:.|..||
  Fly    35 DLDDLLPTIGEFGKYQKLLVFGICLPACIPCGFCAFNQLFMADTPDDYWCRIPELLDLPLEQRKS 99

  Fly    54 ------------------DYQPNSTSLL------SCSVMQFDKEF---KC-TSWDFERESNYESI 90
                              .|..|.|.||      ..:.|:.:..:   || ..|::.....:.||
  Fly   100 LSIPKELDNDELVYSKCYTYGVNWTQLLESGEEDDLTTMEPNASWPLIKCPQGWEYNTSVVWSSI 164

  Fly    91 TTELEWVCDDAYKLAVGQSFFFIGSALGSIFFGYLADRIGRLPA---CVLSTLTGA-----SGDF 147
            ..:.:.|||......:|.:....|..:|...||.|.||.||..:   |:.:.|.|:     |.||
  Fly   165 VIDFDLVCDQDIYPTIGLAALNTGGPVGVYLFGLLNDRGGRRLSYFVCLATLLAGSLMTSLSKDF 229

  Fly   148 FTSFVGSLPWFSFTRFISGLFMDTQYVLMYILVFEYLSPQHRTFGLNIILGVFYCVGLMISPWIA 212
            :| :.||       |.|.||.:...|.:.:|:..|.:...:|:| :.::...||..|:|:...:.
  Fly   230 WT-WAGS-------RVIVGLTIPAVYQIPFIISLELVGENYRSF-VTVMTCTFYTSGIMLLSGVT 285

  Fly   213 IWVTNWRNYLWAASLPALGMLLFPVFLHESAEWLLTKGKFEKAEKSLRGVAKFNGRQVDDSV--- 274
            ....:|....:..|||.....|:...:.||..|||.:|:.|:|.|.|..:||.|||:..::|
  Fly   286 YLERDWVRLSYITSLPFYAYFLYMFVMPESPRWLLMRGRLEEALKILERMAKVNGREFPEAVHLK 350

  Fly   275 FDEFIKHYREKLNNSQNKSSDTFMG-MLRTPRLRKFTIILLIKSMIITIAFDILSRNVEGVGISP 338
            .:..|:  |:||...:.|.::..:. :.|||.:|..||::.:........:..||.....:|.:.
  Fly   351 LEAQIR--RDKLKKQKKKMANVGLADLCRTPNMRLKTILITLSWFANETVYLGLSYYGPALGTNQ 413

  Fly   339 FKLFSYSGFCYLPAGLTIILFQNKIGRKGMACASLFVGAIITAATGYLVATLDPSDY--SVLLGF 401
            :..|..|....||:.|....|.:..||:.....|:.:|.:....|..|     |.|.  ..|:.:
  Fly   414 YVSFFLSAVVELPSYLCCWYFMDTWGRRWPLSLSMILGGVACVITVML-----PDDAVDETLVLY 473

  Fly   402 MVSLGRYGA--VVAYDAEAQYAAEIIPTSVKGRGVANIHVVGNAFAFFSSYIIYLGTFYKPLPSL 464
            :||.....|  ::.|    .:|.|:.||.|:|.|:.....:|........:|.|||.....||.:
  Fly   474 LVSKALLSASFLIIY----PFAGELYPTQVRGIGIGASSYIGGLGLIGIPFITYLGKDNLKLPLV 534

  Fly   465 MISFILLIGACLCLALPETLHKNLPQNLEEGEMFAKGEKWYFFPC--FSRRPKTQKSATQLESSD 527
            ::.|:.::|....|.||||||..|||.:||||.|  |:.|.|..|  .:::|:........|:.|
  Fly   535 IMGFLSMLGGMTGLRLPETLHHRLPQTIEEGEEF--GKNWQFKDCCRCAQKPEILSQPASYENLD 597

Fly 528 527
Fly 598 597

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17751	NP_650816.3	2A0119	11..490	CDD:273328	139/535 (26%)
CG17751	NP_650816.3	MFS	109..481	CDD:119392	102/387 (26%)
CarT	NP_610052.1	2A0119	44..561	CDD:273328	140/536 (26%)
CarT	NP_610052.1	MFS	182..551	CDD:119392	102/388 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	3	3.010