Protein Alignment CG17751 and SLC22A24

DIOPT Version :9

• Sequence 1: NP_650816.3
• Gene: CG17751 / 42336
• FlyBaseID: FBgn0038717
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_001129978.2
• Gene: SLC22A24 / 283238
• HGNCID: 28542
• Length: 552
• Species: Homo sapiens
• Alignment Length: 543
• Identity: 138/543 - (25%)
• Similarity: 238/543 - (43%)
• Gaps: 59/543 - (10%)

  Fly     1 MDLQSVLEKCGNFGPYQILLLGLFGYTNIVSSLHYFSQTIISFTPSHRCSRP----EDYQPNSTS 61
            |....:|::.|..|.:||.|:..|..|||:...:...:...:|||||||..|    :....|.|.
Human     1 MGFDVLLDQVGGMGRFQICLIAFFCITNILLFPNIVLENFTAFTPSHRCWVPLLDNDTVSDNDTG 65

  Fly    62 LLS-------------------C--------SVMQFDKEFKCTS----------WDFERESNYES 89
            .||                   |        .::..:..|..|:          |.::|.|...:
Human    66 TLSKDDLLRISIPLDSNLRPQKCQRFIHPQWQLLHLNGTFPNTNEPDTEPCVDGWVYDRSSFLST 130

  Fly    90 ITTELEWVCDDAYKLAVGQSFFFIGSALGSIFFGYLADRIGRLPACVLSTLTGASGDFFTSFVGS 154
            |.||.:.||:.....::.||.|..||.||.:.:|:|:||:||...|.|..|..|..:...:|..:
Human   131 IVTEWDLVCESQSLKSMVQSLFMAGSLLGGLIYGHLSDRVGRKIICKLCFLQLAISNTCAAFAPT 195

  Fly   155 LPWFSFTRFISGLFMDTQYVLMYILVFEYLSPQHRTFGLNIILGVFYCVGLMISPWIAIWVTNWR 219
            ...:...||::|....|.....:||..|:..|:.|:..:.::| ..|.||.|:...:|..:.:|.
Human   196 FLVYCILRFLAGFSTMTILGNTFILSLEWTLPRSRSMTIMVLL-CSYSVGQMLLGGLAFAIQDWH 259

  Fly   220 NYLWAASLPALGMLLFPVFLHESAEWLLTKGKFEKAEKSLRGVAKFNGRQ-VDDSVFDEFIKH-Y 282
            ......|.|.:.:.|....:.|||.||:...:.::..|.||.||..||:: .::::..|.::. .
Human   260 ILQLTVSTPIIVLFLSSWKMVESARWLIINNQLDEGLKELRRVAHINGKKNTEETLTTELVRSTM 324

  Fly   283 REKLNNSQNKSSDTFMGMLRTPRLRKFTIILLIKSMIITIAFDILSRNVEGVG--ISPFKLFSYS 345
            :::|:..:.|:|  ...:.|.|:||.....|......||:.|..|..|::.:|  :|.|::.  .
Human   325 KKELDAVRIKTS--IFSLFRAPKLRMRVFGLCFVRFAITVPFYGLILNLQHLGSNVSLFQIL--C 385

  Fly   346 GFCYLPAGLTIILFQNKIGRKGMACASLF-VGAIITAATGYLVATLDPSDYSVLLGFMVSLGRYG 409
            |.....|....:|..|.:||:.......| ||..|      ||.|..|.:..:|...:.:||...
Human   386 GAVTFTARCVSLLTLNHMGRRISQILFTFPVGLFI------LVNTFLPQEMQILRVVLATLGIGS 444

  Fly   410 AVVAYDAEAQYAAEIIPTSVKGRGVANIHVV-GNAFAFFSSYIIYLGTFYKPLPSLMISFILLIG 473
            ...|.::.:.:..|::||.::.. ||.|:.| |...|..:..::.|..:...||.:......::.
Human   445 VSAASNSASVHHNELVPTILRST-VAGINAVSGRTGAALAPLLMTLMAYSPHLPWISYGVFPILA 508

  Fly   474 ACLCLALPETLHKNLPQNLEEGE 496
            ..:.|.||||....||..:::.|
Human   509 VPVILLLPETRDLPLPNTIQDVE 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17751	NP_650816.3	2A0119	11..490	CDD:273328	134/525 (26%)
		MFS	109..481	CDD:119392	96/377 (25%)
SLC22A24	NP_001129978.2	MFS_OAT	109..516	CDD:340932	105/418 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153836
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.950