Protein Alignment CG17751 and Slc22a8

DIOPT Version :9

• Sequence 1: NP_650816.3
• Gene: CG17751 / 42336
• FlyBaseID: FBgn0038717
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_001158106.1
• Gene: Slc22a8 / 19879
• MGIID: 1336187
• Length: 537
• Species: Mus musculus
• Alignment Length: 579
• Identity: 146/579 - (25%)
• Similarity: 238/579 - (41%)
• Gaps: 93/579 - (16%)

  Fly     1 MDLQSVLEKCGNFGPYQ-----ILLLGLFGYTNIVSSLHYFSQTIISFTPSHRCSRPEDYQPNST 60
            |....:|::.|:.||:|     :|.|.:.|..|     |...|...:.||.|.|..|    ||::
Mouse     1 MTFSEILDRVGSMGPFQYLHVTLLALPILGIAN-----HNLLQIFTATTPDHHCRPP----PNAS 56

  Fly    61 SLLSCSVMQF---DKEFKC-----------------------TSWDFERESNYESITTELEWVCD 99
              |...|:..   .|..||                       ..|.:  .|..::|.||.:.||.
Mouse    57 --LEPWVLPLGPNGKPEKCLRFVHLPNASLPNDTQGATEPCLDGWIY--NSTRDTIVTEWDLVCG 117

  Fly   100 DAYKLAVGQSFFFIGSALGSIFFGYLADRIGRLPACVLSTLTGASGDFFTSFVGSLPWFSFTRF- 163
            ......:.||.|..|..:|...||.|:||.||.|....|.|..|:.....:|..||..:...||
Mouse   118 SNKLKEMAQSVFMAGILVGGPVFGELSDRFGRKPILTWSYLLLAASGSSAAFSPSLTVYMIFRFL 182

  Fly   164 ----ISGLFMDTQYVLMYILVFEYLSPQHRTFGLNIILGVFYCVGLMISPWIAIWVTNWRNYLWA 224
                |||:.:.|     .||..|::....|... :..:|..|.:|..|.|.:|..|..||   |.
Mouse   183 CGCSISGISLST-----IILNVEWVPTSTRAIS-STTIGYCYTIGQFILPGLAYAVPQWR---WL 238

  Fly   225 ASLPALGMLLFPV---FLHESAEWLLTKGKFEKAEKSLRGVAKFNGRQVDDS--VFDEFIKHYRE 284
            ....:....:|.:   ::.||..||:..|||.||.|:|:.||.|||::.:..  ..:|...:.::
Mouse   239 QLSVSAAFFIFSLLSWWVPESIRWLVLSGKFSKALKTLQRVATFNGKKEEGEKLTVEELKFNLQK 303

  Fly   285 KLNNSQNK--SSDTFMGMLRTPRLRKFTIILLIKSMIITIAFDILSRNVEGVGISPFKLFSYSGF 347
            .:.:::.|  .||.|    |...||:.|..|.:.......|:..|:..||..|::.:.|....|.
Mouse   304 DITSAKVKYGLSDLF----RVSILRRVTFCLSLAWFATGFAYYSLAMGVEEFGVNIYILQIIFGG 364

  Fly   348 CYLPAGLTIILFQNKIGRKGMACASLFVG-AIITAATGYLVATLDPSDYSVLLGFMVSLGRYGAV 411
            ..:||....||..:.:||:      :..| .:|.|....|......|:..:|...:...|:....
Mouse   365 VDIPAKFITILSISYLGRR------ITQGFLLILAGVAILALIFVSSEMQLLRTALAVFGKGCLS 423

  Fly   412 VAYDAEAQYAAEIIPTSVK--GRGVANIHV-VGNAFAFFSSYIIYLGTFYKPLPSLMISFILLIG 473
            .::.....|.:|:.||.::  |.|::||.. ||:..|   ..:...|.....:|:::...:.|:|
Mouse   424 GSFSCLFLYTSELYPTVLRQTGMGISNIWARVGSMIA---PLVKITGELQPFIPNVIFGTMTLLG 485

  Fly   474 ACLCLALPETLHKNLPQNLEEGEMFAKGEKWYFFPCFSRRPKTQKSATQLESSDGITNK 532
            ......|.|||::.||:.:|:      .:.||     .:..||::.....::|..|..|
Mouse   486 GSAAFFLLETLNRPLPETIED------IQDWY-----QQTKKTKQEPEAEKASQTIPLK 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17751	NP_650816.3	2A0119	11..490	CDD:273328	135/525 (26%)
		MFS	109..481	CDD:119392	100/387 (26%)
Slc22a8	NP_001158106.1	2A0119	11..503	CDD:273328	136/526 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	513..537		5/21 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844026
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.950