DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17751 and suex-2

DIOPT Version :9

Sequence 1:	NP_650816.3	Gene:	CG17751 / 42336	FlyBaseID:	FBgn0038717	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_501556.2	Gene:	suex-2 / 183742	WormBaseID:	WBGene00008271	Length:	502	Species:	Caenorhabditis elegans

Alignment Length:	509	Identity:	124/509 - (24%)
Similarity:	190/509 - (37%)	Gaps:	121/509 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 YQILLLGLFGYTNIVSSLHYFSQTII-----SFTPSHRCSRPE-----------DYQPNSTSLLS 64
            |||.|:              ||..:|     .|.||..|:...           ||..|:.:|
Worm    15 YQITLI--------------FSAQLIFVIFLDFMPSTYCTDDNFCYKLQSKCLMDYDHNAQNL-- 63

  Fly    65 CSVMQFDKEFKCTSWDFER------ESNYESITTELEWVCDDAYKLAVGQSFFFIGSALGSIFFG 123
            |.|...:...||.: |..|      :..|:...|.|     :.:.|:...   |||:.||:|..|
Worm    64 CPVNMTENASKCIA-DHSRLFFRSAQFEYQQDCTGL-----NGFSLSTAT---FIGTLLGNIALG 119

  Fly   124 YLADRIGRLPACVLSTLTGASGDFFTSFVGSLPWFSFTRFISGLFMDTQYVLMYILVFEYLSPQH 188
            :|||:.||....:.|.|.|......::.:.::..|...|.:.|:.:.....:.:....|.:||..
Worm   120 FLADKYGRRTIYLSSLLFGIPCVVLSAAITNIYSFYIFRILIGISVSGTLTVGWTYATEMISPNR 184

  Fly   189 RTFGLNIILGVFYCVGLMISPWIAIWVTNWR--NYLWAA----SLPALGMLLFPVFLHESAEWLL 247
            |   |.|:....:....||...:|.....|:  .|:.||    |||.|      ::|.||..||.
Worm   185 R---LRILAFSNWPNARMIQVGLAYISQEWKTATYICAAVSCLSLPIL------IYLPESPIWLD 240

  Fly   248 TKGKFE---KAEKSLRGVAKFNGRQVDDSVFDEFIKHYREKLNNSQNKSSDTFMGMLRTPRLRKF 309
            .|.|::   ||.|.||.:.||...:....|              :..|.:.|  .:|:.|:||..
Worm   241 QKQKYKNASKARKRLRKIGKFYSNEHSTVV--------------ANRKFTPT--RILKDPKLRNS 289

  Fly   310 TIILLIKSMIITIAFDILSRNVEGVGISPFKLFSYSGFCYLPAGLTIILFQNKIGR-----KGMA 369
            ..:::.....:.:|..|...|    |....|......|.   :||.:.:.|..||.     .|:.
Worm   290 FFMIIFMYFYVGLAVYITDLN----GADMTKNLYLGQFL---SGLVLSIAQFIIGMTEPYLTGLG 347

  Fly   370 CASLFVGAIITAATGYLVATLDPSDYSVLLGFMVSLGRYGAVVAYDA---EAQYAA--EIIPTSV 429
            ...||:.|...|...|:...:  ..|....|..:.|..|....|..:   ||.|.:  |::||.|
Worm   348 RRVLFLIAQFIAMLCYICILI--CLYLNWKGSFLYLSAYTLAYATQSLCLEAAYLSLVELMPTDV 410

  Fly   430 KGR--GVANIHV-VGNAFAFFSSYIIYLGTFYKPL-----PSLMISFILLIGAC 475
            :..  ..|||.: :|.          .|.|..|||     |||   |.:.:..|
Worm   411 RATAGSTANICMKIGT----------ILATLTKPLKFAYEPSL---FFINLSIC 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17751	NP_650816.3	2A0119	11..490	CDD:273328	124/509 (24%)
CG17751	NP_650816.3	MFS	109..481	CDD:119392	99/394 (25%)
suex-2	NP_501556.2	MFS	108..460	CDD:391944	99/391 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910